Details for: Orco

Gene ID: 40650

Symbol: Orco

Ensembl ID: FBgn0037324

Description: Odorant receptor co-receptor

Associated with

Other Information

Genular Protein ID: 2718278024

Symbol: ORCO_DROME

Name: Odorant receptor coreceptor

UniProtKB Accession Codes:

Q9VNB5 A8JQT8 Q672R0

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 EMBL 3 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 1 GO 15 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 2 SMR 1 STRING 1 TCDB 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 15339651

Title: Or83b encodes a broadly expressed odorant receptor essential for Drosophila olfaction.

PubMed ID: 15339651

DOI: 10.1016/j.neuron.2004.08.019

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10089887

Title: A spatial map of olfactory receptor expression in the Drosophila antenna.

PubMed ID: 10089887

DOI: 10.1016/s0092-8674(00)80582-6

PubMed ID: 10943836

Title: An olfactory sensory map in the fly brain.

PubMed ID: 10943836

DOI: 10.1016/s0092-8674(00)00021-0

PubMed ID: 15592462

Title: Odorant receptor heterodimerization in the olfactory system of Drosophila melanogaster.

PubMed ID: 15592462

DOI: 10.1038/nn1371

PubMed ID: 16402857

Title: Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo.

PubMed ID: 16402857

DOI: 10.1371/journal.pbio.0040020

PubMed ID: 18005664

Title: Membrane topology of the Drosophila OR83b odorant receptor.

PubMed ID: 18005664

DOI: 10.1016/j.febslet.2007.11.007

PubMed ID: 17943085

Title: An essential role for a CD36-related receptor in pheromone detection in Drosophila.

PubMed ID: 17943085

DOI: 10.1038/nature06328

PubMed ID: 18408712

Title: Insect olfactory receptors are heteromeric ligand-gated ion channels.

PubMed ID: 18408712

DOI: 10.1038/nature06850

PubMed ID: 18408711

Title: Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels.

PubMed ID: 18408711

DOI: 10.1038/nature06861

PubMed ID: 20147286

Title: Transmembrane segment 3 of Drosophila melanogaster odorant receptor subunit 85b contributes to ligand-receptor interactions.

PubMed ID: 20147286

DOI: 10.1074/jbc.m109.058321

PubMed ID: 21677030

Title: Subunit contributions to insect olfactory receptor function: channel block and odorant recognition.

PubMed ID: 21677030

DOI: 10.1093/chemse/bjr053

PubMed ID: 21937991

Title: A natural polymorphism alters odour and DEET sensitivity in an insect odorant receptor.

PubMed ID: 21937991

DOI: 10.1038/nature10438

Sequence Information:

  • Length: 486
  • Mass: 54413
  • Checksum: 8DD0ACDC3091B5D6
  • Sequence:
    • MTTSMQPSKY TGLVADLMPN IRAMKYSGLF MHNFTGGSAF MKKVYSSVHL VFLLMQFTFI 
LVNMALNAEE VNELSGNTIT TLFFTHCITK FIYLAVNQKN FYRTLNIWNQ VNTHPLFAES 
DARYHSIALA KMRKLFFLVM LTTVASATAW TTITFFGDSV KMVVDHETNS SIPVEIPRLP 
IKSFYPWNAS HGMFYMISFA FQIYYVLFSM IHSNLCDVMF CSWLIFACEQ LQHLKGIMKP 
LMELSASLDT YRPNSAALFR SLSANSKSEL IHNEEKDPGT DMDMSGIYSS KADWGAQFRA 
PSTLQSFGGN GGGGNGLVNG ANPNGLTKKQ EMMVRSAIKY WVERHKHVVR LVAAIGDTYG 
AALLLHMLTS TIKLTLLAYQ ATKINGVNVY AFTVVGYLGY ALAQVFHFCI FGNRLIEESS 
SVMEAAYSCH WYDGSEEAKT FVQIVCQQCQ KAMSISGAKF FTVSLDLFAS VLGAVVTYFM 
VLVQLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.