Details for: Sym

Gene ID: 40709

Symbol: Sym

Ensembl ID: FBgn0037371

Description: Symplekin

Associated with

Other Information

Genular Protein ID: 1785106950

Symbol: SYMPK_DROME

Name: N/A

UniProtKB Accession Codes:

Q8MSU4 Q9VNH4

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ComplexPortal 1 DNASU 1 EMBL 4 EnsemblMetazoa 1 EvolutionaryTrace 1 FlyBase 1 GO 7 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 5 PRO 1 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 Reactome 5 RefSeq 1 SAM 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 18042462

Title: A genome-wide RNA interference screen reveals that variant histones are necessary for replication-dependent histone pre-mRNA processing.

PubMed ID: 18042462

DOI: 10.1016/j.molcel.2007.10.009

PubMed ID: 19450530

Title: A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs.

PubMed ID: 19450530

DOI: 10.1016/j.molcel.2009.04.024

PubMed ID: 29317541

Title: Dicer-2 promotes mRNA activation through cytoplasmic polyadenylation.

PubMed ID: 29317541

DOI: 10.1261/rna.065417.117

PubMed ID: 19576221

Title: Crystal structure of the HEAT domain from the Pre-mRNA processing factor Symplekin.

PubMed ID: 19576221

DOI: 10.1016/j.jmb.2009.06.062

Sequence Information:

  • Length: 1165
  • Mass: 132077
  • Checksum: CFA818C50B2CC847
  • Sequence:
    • MDSIIGRSQF VSETANLFTD EKTATARAKV VDWCNELVIA SPSTKCELLA KVQETVLGSC 
AELAEEFLES VLSLAHDSNM EVRKQVVAFV EQVCKVKVEL LPHVINVVSM LLRDNSAQVI 
KRVIQACGSI YKNGLQYLCS LMEPGDSAEQ AWNILSLIKA QILDMIDNEN DGIRTNAIKF 
LEGVVVLQSF ADEDSLKRDG DFSLADVPDH CTLFRREKLQ EEGNNILDIL LQFHGTTHIS 
SVNLIACTSS LCTIAKMRPI FMGAVVEAFK QLNANLPPTL TDSQVSSVRK SLKMQLQTLL 
KNRGAFEFAS TIRGMLVDLG SSTNEIQKLI PKMDKQEMAR RQKRILENAA QSLAKRARLA 
CEQQDQQQRE MELDTEELER QKQKSTRVNE KFLAEHFRNP ETVVTLVLEF LPSLPTEVPQ 
KFLQEYTPIR EMSIQQQVTN ISRFFGEQLS EKRLGPGAAT FSREPPMRVK KVQAIESTLT 
AMEVDEDAVQ KLSEEEFQRK EEATKKLRET MERAKGEQTV IEKMKERAKT LKLQEITKPL 
PRNLKEKFLT DAVRRILNSE RQCIKGGVSS KRRKLVTVIA ATFPDNVRYG IMEFILEDIK 
QRIDLAFSWL FEEYSLLQGF TRHTYVKTEN RPDHAYNELL NKLIFGIGER CDHKDKIILI 
RRVYLEAPIL PEVSIGHLVQ LSLDDEFSQH GLELIKDLAV LRPPRKNRFV RVLLNFSVHE 
RLDLRDLAQA HLVSLYHVHK ILPARIDEFA LEWLKFIEQE SPPAAVFSQD FGRPTEEPDW 
REDTTKVCFG LAFTLLPYKP EVYLQQICQV FVSTSAELKR TILRSLDIPI KKMGVESPTL 
LQLIEDCPKG METLVIRIIY ILTERVPSPH EELVRRVRDL YQNKVKDVRV MIPVLSGLTR 
SELISVLPKL IKLNPAVVKE VFNRLLGIGA EFAHQTMAMT PTDILVALHT IDTSVCDIKA 
IVKATSLCLA ERDLYTQEVL MAVLQQLVEV TPLPTLMMRT TIQSLTLYPR LANFVMNLLQ 
RLIIKQVWRQ KVIWEGFLKT VQRLKPQSMP ILLHLPPAQL VDALQQCPDL RPALSEYAES 
MQDEPMNGSG ITQQVLDIIS GKSVDVFVTD ESGGYISAEH IKKEAPDPSE ISVISTVPVL 
TSLVPLPVPP PIGSDLNQPL PPGED

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.