Details for: Dfd

Gene ID: 40832

Symbol: Dfd

Ensembl ID: FBgn0000439

Description: Deformed

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription factor binding
    (GO:0140297)
  • Dna binding
    (GO:0003677)
  • Embryonic brain development
    (GO:1990403)
  • Head development
    (GO:0060322)
  • Head morphogenesis
    (GO:0060323)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neuronal cell body
    (GO:0043025)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of apoptotic process involved in morphogenesis
    (GO:1902339)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Posterior head segmentation
    (GO:0035289)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of gene expression
    (GO:0010468)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific dna binding
    (GO:0043565)
  • Specification of segmental identity, head
    (GO:0007380)

Other Information

Genular Protein ID: 134486807

Symbol: DFD_DROME

Name: Homeotic protein deformed

UniProtKB Accession Codes:

P07548 Q9UAL9 Q9VI48

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 DNASU 1 EMBL 4 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 1 GO 19 Gene3D 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 3 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 16453752

Title: Developmental and molecular analysis of Deformed: a homeotic gene controlling Drosophila head development.

PubMed ID: 16453752

DOI: 10.1002/j.1460-2075.1987.tb04819.x

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 3938363

Title: Common properties of proteins encoded by the Antennapedia complex genes of Drosophila melanogaster.

PubMed ID: 3938363

DOI: 10.1101/sqb.1985.050.01.032

PubMed ID: 2416463

Title: Homeo box genes of the Antennapedia and bithorax complexes of Drosophila.

PubMed ID: 2416463

DOI: 10.1016/0092-8674(85)90013-3

PubMed ID: 12202035

Title: The Drosophila Hox gene deformed sculpts head morphology via direct regulation of the apoptosis activator reaper.

PubMed ID: 12202035

DOI: 10.1016/s0092-8674(02)00871-1

PubMed ID: 12492146

Title: Hox genes and the evolution of the arthropod body plan.

PubMed ID: 12492146

DOI: 10.1046/j.1525-142x.2002.02034.x

Sequence Information:

  • Length: 586
  • Mass: 63380
  • Checksum: 9A7C79C744FAFF18
  • Sequence:
    • MSSFLMGYPH APHHVQSPMS MGNGLDPKFP PLADDYHHYN GHYSMTASTG HMSGAVGGGA 
GVGSVGGGGA GGMTGHPHSM HPADMVSDYM AHHHNPHSHS HSHTHSLPHH HSNSAISGHH 
QASAGGYSSN YANATPPSHP HSHPHAHPHQ SLGYYVHHAP EFISAGAVHS DPTNGYGPAA 
NVPNTSNGGG GGGSGAVLGG GAVGGSANGY YGGYGGGYGT ANGSVGSTHS QGHSPHSQMM 
DLPLQCSSTE PPTNTALGLQ ELGLKLEKRI EEAVPAGQQL QELGMRLRCD DMGSENDDMS 
EEDRLMLDRS PDELGSNDND DDLGDSDSDE DLMAETTDGE RIIYPWMKKI HVAGVANGSY 
QPGMEPKRQR TAYTRHQILE LEKEFHYNRY LTRRRRIEIA HTLVLSERQI KIWFQNRRMK 
WKKDNKLPNT KNVRKKTVDA NGNPTPVAKK PTKRAASKKQ QQAQQQQQSQ QQQTQQTPVM 
NECIRSDSLE SIGDVSSSLG NPPYIPAAPE TTSSYPGSQQ HLSNNNNNGS GNNNNNNNNN 
NSNLNNNNNN NQMGHTNLHG HLQQQQSDLM TNLQLHIKQD YDLTAL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.