Details for: Scr

Gene ID: 40833

Symbol: Scr

Ensembl ID: FBgn0003339

Description: Sex combs reduced

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Midgut development
    (GO:0007494)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein homodimerization activity
    (GO:0042803)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Salivary gland boundary specification
    (GO:0007432)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sex comb development
    (GO:0045498)

Other Information

Genular Protein ID: 2885614641

Symbol: SCR_DROME

Name: Homeotic protein Sex combs reduced

UniProtKB Accession Codes:

P09077 Q23990 Q24508 Q9V3Q3

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 EMBL 7 EnsemblMetazoa 2 EvolutionaryTrace 1 ExpressionAtlas 1 FlyBase 1 GO 12 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PDB 3 PDBsum 2 PIR 1 PRINTS 2 PRO 1 PROSITE 3 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 2565809

Title: The homeotic gene Sex Combs Reduced of Drosophila: gene structure and embryonic expression.

PubMed ID: 2565809

DOI: 10.1002/j.1460-2075.1989.tb03367.x

PubMed ID: 7835693

Title: The sex combs reduced gene of Drosophila melanogaster has multiple transcripts.

PubMed ID: 7835693

DOI: 10.1016/0378-1119(94)00642-6

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 16453653

Title: Cloning of the homeotic Sex Combs Reduced gene in Drosophila and in situ localization of its transcripts.

PubMed ID: 16453653

DOI: 10.1002/j.1460-2075.1985.tb04145.x

PubMed ID: 1743486

Title: A functional and structural analysis of the Sex combs reduced locus of Drosophila melanogaster.

PubMed ID: 1743486

DOI: 10.1093/genetics/129.2.423

PubMed ID: 12492146

Title: Hox genes and the evolution of the arthropod body plan.

PubMed ID: 12492146

DOI: 10.1046/j.1525-142x.2002.02034.x

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

  • Length: 417
  • Mass: 44263
  • Checksum: 8A3A58A60E0B32BE
  • Sequence:
    • MDPDCFAMSS YQFVNSLASC YPQQMNPQQN HPGAGNSSAG GSGGGAGGSG GVVPSGGTNG 
GQGSAGAATP GANDYFPAAA AYTPNLYPNT PQAHYANQAA YGGQGNPDMV DYTQLQPQRL 
LLQQQQQQQQ QQHAHAAAAV AAQQQQQLAQ QQHPQQQQQQ QQANISCKYA NDPVTPGGSG 
GGGVSGSNNN NNSANSNNNN SQSLASPQDL STRDISPKLS PSSVVESVAR SLNKGVLGGS 
LAAAAAAAGL NNNHSGSGVS GGPGNVNVPM HSPGGGDSDS ESDSGNEAGS SQNSGNGKKN 
PPQIYPWMKR VHLGTSTVNA NGETKRQRTS YTRYQTLELE KEFHFNRYLT RRRRIEIAHA 
LCLTERQIKI WFQNRRMKWK KEHKMASMNI VPYHMGPYGH PYHQFDIHPS QFAHLSA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.