Details for: ftz

Gene ID: 40834

Symbol: ftz

Ensembl ID: FBgn0001077

Description: fushi tarazu

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Cell fate specification
    (GO:0001708)
  • Central nervous system development
    (GO:0007417)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Germ cell migration
    (GO:0008354)
  • Gonadal mesoderm development
    (GO:0007506)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Periodic partitioning by pair rule gene
    (GO:0007366)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Segmentation
    (GO:0035282)

Other Information

Genular Protein ID: 1391347189

Symbol: FTZ_DROME

Name: Segmentation protein fushi tarazu

UniProtKB Accession Codes:

P02835 O96929 Q4V6Y3 Q9V3W3

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 DNASU 1 EMBL 6 EnsemblMetazoa 1 EvolutionaryTrace 1 FlyBase 1 GO 14 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 6330566

Title: Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins.

PubMed ID: 6330566

DOI: 10.1038/310025a0

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 2276626

Title: Mutations affecting the stability of the fushi tarazu protein of Drosophila.

PubMed ID: 2276626

DOI: 10.1101/gad.4.11.1936

PubMed ID: 6327065

Title: A homologous protein-coding sequence in Drosophila homeotic genes and its conservation in other metazoans.

PubMed ID: 6327065

DOI: 10.1016/0092-8674(84)90370-2

PubMed ID: 6330741

Title: Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of Drosophila.

PubMed ID: 6330741

DOI: 10.1073/pnas.81.13.4115

PubMed ID: 2892267

Title: Expression and function of the segmentation gene fushi tarazu during Drosophila neurogenesis.

PubMed ID: 2892267

DOI: 10.1126/science.2892267

PubMed ID: 3049237

Title: Expression, modification, and localization of the fushi tarazu protein in Drosophila embryos.

PubMed ID: 3049237

DOI: 10.1101/gad.2.8.1021

PubMed ID: 2743978

Title: Stage-specific phosphorylation of the fushi tarazu protein during Drosophila development.

PubMed ID: 2743978

DOI: 10.1002/j.1460-2075.1989.tb03492.x

PubMed ID: 7909851

Title: Nuclear magnetic resonance solution structure of the fushi tarazu homeodomain from Drosophila and comparison with the Antennapedia homeodomain.

PubMed ID: 7909851

DOI: 10.1006/jmbi.1994.1296

Sequence Information:

  • Length: 410
  • Mass: 46479
  • Checksum: 517154F3DAF8262F
  • Sequence:
    • MATTNSQSHY SYADNMNMYN MYHPHSLPPT YYDNSGSNAY YQNTSNYQGY YPQESYSESC 
YYYNNQEQVT TQTVPPVQPT TPPPKATKRK AEDDAASIIA AVEERPSTLR ALLTNPVKKL 
KYTPDYFYTT VEQVKKAPAV STKVTASPAP SYDQEYVTVP TPSASEDVDY LDVYSPQSQT 
QKLKNGDFAT PPPTTPTSLP PLEGISTPPQ SPGEKSSSAV SQEINHRIVT APNGAGDFNW 
SHIEETLASD CKDSKRTRQT YTRYQTLELE KEFHFNRYIT RRRRIDIANA LSLSERQIKI 
WFQNRRMKSK KDRTLDSSPE HCGAGYTAML PPLEATSTAT TGAPSVPVPM YHHHQTTAAY 
PAYSHSHSHG YGLLNDYPQQ QTHQQYDAYP QQYQHQCSYQ QHPQDLYHLS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.