Details for: Sp7

Gene ID: 40918

Symbol: Sp7

Ensembl ID: FBgn0037515

Description: Serine protease 7

Associated with

Other Information

Genular Protein ID: 3271505161

Symbol: SER7_DROME

Name: N/A

UniProtKB Accession Codes:

Q9V3Z2 F7VJU2 Q6BD09 Q9I7L2

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 4 DNASU 1 EMBL 9 EnsemblMetazoa 3 ExpressionAtlas 1 FlyBase 2 GO 8 Gene3D 2 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 8 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 4 PROSITE-ProRule 3 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 2 RefSeq 3 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 UCSC 2 UniProtKB 2 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 15579698

Title: Evolutionary expressed sequence tag analysis of Drosophila female reproductive tracts identifies genes subjected to positive selection.

PubMed ID: 15579698

DOI: 10.1534/genetics.104.030478

PubMed ID: 16256951

Title: The serine protease Sp7 is expressed in blood cells and regulates the melanization reaction in Drosophila.

PubMed ID: 16256951

DOI: 10.1016/j.bbrc.2005.10.042

PubMed ID: 16322759

Title: Prophenoloxidase activation is not required for survival to microbial infections in Drosophila.

PubMed ID: 16322759

DOI: 10.1038/sj.embor.7400592

PubMed ID: 16861233

Title: Two proteases defining a melanization cascade in the immune system of Drosophila.

PubMed ID: 16861233

DOI: 10.1074/jbc.m601642200

PubMed ID: 18854145

Title: A serpin that regulates immune melanization in the respiratory system of Drosophila.

PubMed ID: 18854145

DOI: 10.1016/j.devcel.2008.08.017

PubMed ID: 19071960

Title: A signaling protease required for melanization in Drosophila affects resistance and tolerance of infections.

PubMed ID: 19071960

DOI: 10.1371/journal.pbio.0060305

PubMed ID: 22227521

Title: Genetic evidence of a redox-dependent systemic wound response via Hayan protease-phenoloxidase system in Drosophila.

PubMed ID: 22227521

DOI: 10.1038/emboj.2011.476

PubMed ID: 24260243

Title: Serine protease MP2 activates prophenoloxidase in the melanization immune response of Drosophila melanogaster.

PubMed ID: 24260243

DOI: 10.1371/journal.pone.0079533

Sequence Information:

  • Length: 391
  • Mass: 43128
  • Checksum: 3E1416F12EDF89F6
  • Sequence:
    • MKSTRKVVGI FLATCLLPFT VLQNVAAQGS CRNPNQKQGQ CLSIYDCQSL LSVIQQSYVS 
PEDRTFLRNS QCLDGVGRQP YVCCTSDRSF GSQEATSAAP PPTTTSSSSR GQDGQAGLGN 
LLPSPPKCGP HSFSNKVYNG NDTAIDEFNW MALLEYVDNR GRRELSCGGS LINNRYVLTA 
AHCVIGAVET EVGHLTTVRL GEYDTSKDVD CIDDICNQPI LQLGIEQATV HPQYDPANKN 
RIHDIALLRL DRPVVLNEYI QPVCLPLVST RMAINTGELL VVSGWGRTTT ARKSTIKQRL 
DLPVNDHDYC ARKFATRNIH LISSQLCVGG EFYRDSCDGD SGGPLMRRGF DQAWYQEGVV 
SFGNRCGLEG WPGVYTRVAD YMDWIVETIR P

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.