Details for: nac

Gene ID: 40981

Symbol: nac

Ensembl ID: FBgn0265351

Description: neuronally altered carbohydrate

Associated with

  • Asparagine n-linked glycosylation
    (R-DME-446203)
  • Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
    (R-DME-446193)
  • Gdp-fucose biosynthesis
    (R-DME-6787639)
  • Metabolism of proteins
    (R-DME-392499)
  • Post-translational protein modification
    (R-DME-597592)
  • Slc-mediated transmembrane transport
    (R-DME-425407)
  • Synthesis of substrates in n-glycan biosythesis
    (R-DME-446219)
  • Transport of nucleotide sugars
    (R-DME-727802)
  • Transport of small molecules
    (R-DME-382551)
  • Transport of vitamins, nucleosides, and related molecules
    (R-DME-425397)
  • Antiporter activity
    (GO:0015297)
  • Cmp-n-acetylneuraminate transmembrane transport
    (GO:0015782)
  • Cmp-n-acetylneuraminate transmembrane transporter activity
    (GO:0005456)
  • Gdp-fucose import into golgi lumen
    (GO:0036085)
  • Gdp-fucose transmembrane transport
    (GO:0015783)
  • Gdp-fucose transmembrane transporter activity
    (GO:0005457)
  • Gdp-mannose transmembrane transport
    (GO:1990570)
  • Gdp-mannose transmembrane transporter activity
    (GO:0005458)
  • Golgi-associated vesicle
    (GO:0005798)
  • Golgi apparatus
    (GO:0005794)
  • Golgi vesicle transport
    (GO:0048193)
  • Grooming behavior
    (GO:0007625)
  • N-glycan fucosylation
    (GO:0036071)
  • Protein o-linked fucosylation
    (GO:0036066)
  • Udp-galactose transmembrane transport
    (GO:0072334)
  • Udp-galactose transmembrane transporter activity
    (GO:0005459)
  • Udp-glucose transmembrane transport
    (GO:0015786)
  • Udp-glucose transmembrane transporter activity
    (GO:0005460)
  • Udp-glucuronic acid transmembrane transport
    (GO:0015787)
  • Udp-glucuronic acid transmembrane transporter activity
    (GO:0005461)
  • Udp-n-acetylgalactosamine transmembrane transport
    (GO:0015789)
  • Udp-n-acetylgalactosamine transmembrane transporter activity
    (GO:0005463)
  • Udp-n-acetylglucosamine transmembrane transport
    (GO:1990569)
  • Udp-n-acetylglucosamine transmembrane transporter activity
    (GO:0005462)

Other Information

Genular Protein ID: 1181771027

Symbol: FUCT1_DROME

Name: GDP-fucose transporter 1

UniProtKB Accession Codes:

Q9VHT4 Q53YF6

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EnsemblMetazoa 1 FlyBase 1 GO 12 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 Reactome 2 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 TCDB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 19948734

Title: Two pathways for importing GDP-fucose into the endoplasmic reticulum lumen function redundantly in the O-fucosylation of Notch in Drosophila.

PubMed ID: 19948734

DOI: 10.1074/jbc.m109.016964

PubMed ID: 22745127

Title: The Drosophila neurally altered carbohydrate mutant has a defective Golgi GDP-fucose transporter.

PubMed ID: 22745127

DOI: 10.1074/jbc.m112.379313

Sequence Information:

  • Length: 337
  • Mass: 38107
  • Checksum: 1FB7E9C1EC280AD6
  • Sequence:
    • MYKNLEEHNR LVNKYLKIFF VVSLYWCTSI LTVFVNKHLL SSDTVNLGAP LFMSWFQCVV 
STVICFVASR LSRKYPSVFT FPEGNPLDID TFRKILPLSV LYTLMIGANN LSLSYVTVAF 
YYIGRSLTTV FSVVLTYVIL RQRTSFKCLL CCGAIVVGFW LGVDQESLTE VFSWRGTIFG 
VLSSLALAMF SIQTKKSLGY VNQEVWLLSY YNNLYSTLLF LPLIIINGEL ESIITYPHLW 
ASWFWAAMTL SGLCGFAIGF VTALEIKVTS ALTHNISGTA KACAQTVIAT QYYHDVRSAL 
WWTSNVVVLV ASAAYTRVKQ LEMMRQHQQR STATQKA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.