Details for: ASIC1

Gene ID: 41

Symbol: ASIC1

Ensembl ID: ENSG00000110881

Description: acid sensing ion channel subunit 1

Associated with

Other Information

Genular Protein ID: 3290352283

Symbol: ASIC1_HUMAN

Name: Amiloride-sensitive cation channel 2, neuronal

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9037075

Title: BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels.

PubMed ID: 9037075

DOI: 10.1073/pnas.94.4.1459

PubMed ID: 21036899

Title: Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant.

PubMed ID: 21036899

DOI: 10.1074/jbc.m110.171330

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10798398

Title: Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels.

PubMed ID: 10798398

DOI: 10.1016/s0896-6273(00)81144-7

PubMed ID: 11802773

Title: Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel).

PubMed ID: 11802773

DOI: 10.1042/0264-6021:3610443

PubMed ID: 12244121

Title: Protein kinase C isoform antagonism controls BNaC2 (ASIC1) function.

PubMed ID: 12244121

DOI: 10.1074/jbc.m208995200

PubMed ID: 12578970

Title: cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1.

PubMed ID: 12578970

DOI: 10.1073/pnas.252782799

PubMed ID: 15247234

Title: Selective regulation of acid-sensing ion channel 1 by serine proteases.

PubMed ID: 15247234

DOI: 10.1074/jbc.m407381200

PubMed ID: 19654327

Title: Identification of protein domains that control proton and calcium sensitivity of ASIC1a.

PubMed ID: 19654327

DOI: 10.1074/jbc.m109.029009

PubMed ID: 23034652

Title: Black mamba venom peptides target acid-sensing ion channels to abolish pain.

PubMed ID: 23034652

DOI: 10.1038/nature11494

PubMed ID: 22760635

Title: Structure of the acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1.

PubMed ID: 22760635

DOI: 10.1038/ncomms1917

PubMed ID: 28327374

Title: Discovery and molecular interaction studies of a highly stable, tarantula peptide modulator of acid-sensing ion channel 1.

PubMed ID: 28327374

DOI: 10.1016/j.neuropharm.2017.03.020

Sequence Information:

  • Length: 528
  • Mass: 59909
  • Checksum: 9E998F711C208450
  • Sequence:
  • MELKAEEEEV GGVQPVSIQA FASSSTLHGL AHIFSYERLS LKRALWALCF LGSLAVLLCV 
    CTERVQYYFH YHHVTKLDEV AASQLTFPAV TLCNLNEFRF SQVSKNDLYH AGELLALLNN 
    RYEIPDTQMA DEKQLEILQD KANFRSFKPK PFNMREFYDR AGHDIRDMLL SCHFRGEVCS 
    AEDFKVVFTR YGKCYTFNSG RDGRPRLKTM KGGTGNGLEI MLDIQQDEYL PVWGETDETS 
    FEAGIKVQIH SQDEPPFIDQ LGFGVAPGFQ TFVACQEQRL IYLPPPWGTC KAVTMDSDLD 
    FFDSYSITAC RIDCETRYLV ENCNCRMVHM PGDAPYCTPE QYKECADPAL DFLVEKDQEY 
    CVCEMPCNLT RYGKELSMVK IPSKASAKYL AKKFNKSEQY IGENILVLDI FFEVLNYETI 
    EQKKAYEIAG LLGDIGGQMG LFIGASILTV LELFDYAYEV IKHKLCRRGK CQKEAKRSSA 
    DKGVALSLDD VKRHNPCESL RGHPAGMTYA ANILPHHPAR GTFEDFTC

Genular Protein ID: 2131883218

Symbol: A8K1U5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 528
  • Mass: 59863
  • Checksum: 08CD0D39AA74164C
  • Sequence:
  • MELKAEEEEV GGVQPVSIQA FASSSTLHGL AHIFSYERLS LKRALWALCF LGSLAVLLCV 
    CTERVQYYFH YHHVTKLDEV AASQLTFPAV TLCNLNEFRF SQVSKNDLYH AGELLALLNN 
    RYEIPDTQMA DEKQLEILQD KANFRSFKPK PFNMREFYDR AGHDIRDMLL SCHFRGEVCS 
    AEDFKVVFTR YGKCYTFNSG RDGRPRLKTM KGGTGNGLEI MLDIQQDEYL PVWGETDETS 
    FEAGIKVQIH SQDEPPFIDQ LGFGVAPGFQ TFVACQEQRL IYLPPPWGTC KAVTMDSDLD 
    FFDSYSITAC RIDCETRYLV ENCNCRMLHM PGDAPYCTPE QYKECADPAL DFLVEKDQEY 
    CVCEMPCNLT RYGKELSMVK IPSKASAKYL AKKFNKSEQY IGENILVLDI FFEVLNYETI 
    EQKKAYEIAG LLGDIGGQMG LFIGASILTV LELFDYAYEV IKHKLCRRGK CQKEAKRSSA 
    DKGVALSLDD VKRHNPCESL RGHPAGMTYA ANILPHHPAR GTFEDSTC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.