Details for: hb

Gene ID: 41032

Symbol: hb

Ensembl ID: FBgn0001180

Description: hunchback

Associated with

  • Anterior/posterior axis specification
    (GO:0009948)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Ganglion mother cell fate determination
    (GO:0007402)
  • Generation of neurons
    (GO:0048699)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neuroblast fate determination
    (GO:0007400)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Posterior head segmentation
    (GO:0035289)
  • Regulation of development, heterochronic
    (GO:0040034)
  • Regulation of neural precursor cell proliferation
    (GO:2000177)
  • Regulation of neurogenesis
    (GO:0050767)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Salivary gland development
    (GO:0007431)
  • Sequence-specific dna binding
    (GO:0043565)
  • Trunk segmentation
    (GO:0035290)
  • Ventral cord development
    (GO:0007419)
  • Zygotic determination of anterior/posterior axis, embryo
    (GO:0007354)

Other Information

Genular Protein ID: 3838770598

Symbol: HUNB_DROME

Name: N/A

UniProtKB Accession Codes:

P05084 Q24018 Q29R06 Q960U7

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 DIP 1 DNASU 1 EMBL 5 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 2 GO 22 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 2 SAM 1 SMART 1 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8200478

Title: A small region surrounding the distal promoter of the hunchback gene directs maternal expression.

PubMed ID: 8200478

DOI: 10.1006/dbio.1994.1156

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 1438276

Title: Evolutionary conservation pattern of zinc-finger domains of Drosophila segmentation genes.

PubMed ID: 1438276

DOI: 10.1073/pnas.89.22.10782

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 12572604

Title: Microevolutionary divergence pattern of the segmentation gene hunchback in Drosophila.

PubMed ID: 12572604

DOI: 10.1093/oxfordjournals.molbev.a025868

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

  • Length: 758
  • Mass: 83114
  • Checksum: AD74802EB856ACD7
  • Sequence:
    • MQNWETTATT NYEQHNAWYN SMFAANIKQE PGHHLDGNSV ASSPRQSPIP STNHLEQFLK 
QQQQQLQQQP MDTLCAMTPS PSQNDQNSLQ HYDANLQQQL LQQQQYQQHF QAAQQQHHHH 
HHLMGGFNPL TPPGLPNPMQ HFYGGNLRPS PQPTPTSAST IAPVAVATGS SEKLQALTPP 
MDVTPPKSPA KSSQSNIEPE KEHDQMSNSS EDMKYMAESE DDDTNIRMPI YNSHGKMKNY 
KCKTCGVVAI TKVDFWAHTR THMKPDKILQ CPKCPFVTEF KHHLEYHIRK HKNQKPFQCD 
KCSYTCVNKS MLNSHRKSHS SVYQYRCADC DYATKYCHSF KLHLRKYGHK PGMVLDEDGT 
PNPSLVIDVY GTRRGPKSKN GGPIASGGSG SGSRKSNVAA VAPQQQQSQP AQPVATSQLS 
AALQGFPLVQ GNSAPPAASP VLPLPASPAK SVASVEQTPS LPSPANLLPP LASLLQQNRN 
MAFFPYWNLN LQMLAAQQQA AVLAQLSPRM REQLQQQNQQ QSDNEEEEQD DEYERKSVDS 
AMDLSQGTPV KEDEQQQQPQ QPLAMNLKVE EEATPLMSSS NASRRKGRVL KLDTLLQLRS 
EAMTSPEQLK VPSTPMPTAS SPIAGRKPMP EEHCSGTSSA DESMETAHVP QANTSASSTA 
SSSGNSSNAS SNSNGNSSSN SSSNGTTSAV AAPPSGTPAA AGAIYECKYC DIFFKDAVLY 
TIHMGYHSCD DVFKCNMCGE KCDGPVGLFV HMARNAHS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.