Scm | FBgn0003334 | NCBI 41168

Details for: Scm

Gene ID: 41168

Symbol: Scm

Ensembl ID: FBgn0003334

Description: Sex comb on midleg

Associated with

Cellular responses to stimuli
(R-DME-8953897)
Cellular responses to stress
(R-DME-2262752)
Cellular senescence
(R-DME-2559583)
Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Intracellular signaling by second messengers
(R-DME-9006925)
Metabolism of proteins
(R-DME-392499)
Oxidative stress induced senescence
(R-DME-2559580)
Pip3 activates akt signaling
(R-DME-1257604)
Post-translational protein modification
(R-DME-597592)
Pten regulation
(R-DME-6807070)
Regulation of pten gene transcription
(R-DME-8943724)
Rna polymerase ii transcription
(R-DME-73857)
Runx1 interacts with co-factors whose precise effect on runx1 targets is not known
(R-DME-8939243)
Signal transduction
(R-DME-162582)
Sumo e3 ligases sumoylate target proteins
(R-DME-3108232)
Sumoylation
(R-DME-2990846)
Sumoylation of dna damage response and repair proteins
(R-DME-3108214)
Sumoylation of rna binding proteins
(R-DME-4570464)
Sumoylation of transcription cofactors
(R-DME-3899300)
Transcriptional regulation by runx1
(R-DME-8878171)
Anterior/posterior axis specification
(GO:0009948)
Axonogenesis
(GO:0007409)
Chromatin binding
(GO:0003682)
Compound eye development
(GO:0048749)
Follicle cell of egg chamber stalk formation
(GO:0030713)
Germarium-derived female germ-line cyst encapsulation
(GO:0030708)
Heterochromatin formation
(GO:0031507)
Histone binding
(GO:0042393)
Identical protein binding
(GO:0042802)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of growth
(GO:0045926)
Neurogenesis
(GO:0022008)
Nucleus
(GO:0005634)
Polytene chromosome
(GO:0005700)
Prc1 complex binding
(GO:0140259)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Sequence-specific dna binding
(GO:0043565)
Ventral cord development
(GO:0007419)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Polycomb protein Scm

Genular Protein ID: 4148474963

Symbol: SCM_DROME

Name: Polycomb protein Scm

UniProtKB Accession Codes:

Q9VHA0 Q24191

Database IDs:

Citations:

PubMed ID: 8625848

Title: The Drosophila polycomb group gene Sex comb on midleg (Scm) encodes a zinc finger protein with similarity to polyhomeotic protein.

PubMed ID: 8625848

DOI: 10.1242/dev.122.5.1621

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 9343432

Title: A domain shared by the polycomb group proteins Scm and ph mediates heterotypic and homotypic interactions.

PubMed ID: 9343432

DOI: 10.1128/mcb.17.11.6683

PubMed ID: 12771214

Title: The Drosophila Corto protein interacts with Polycomb-group proteins and the GAGA factor.

PubMed ID: 12771214

DOI: 10.1093/nar/gkg381

PubMed ID: 15280237

Title: Requirement for sex comb on midleg protein interactions in Drosophila polycomb group repression.

PubMed ID: 15280237

DOI: 10.1534/genetics.104.027474

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 15905166

Title: Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.

PubMed ID: 15905166

DOI: 10.1074/jbc.m503055200

Sequence Information:

Length: 877
Mass: 93551
Checksum: 7859FD0C7B91589E
Sequence:

MSGGRDSSTS SGSNSAAPGA STNATSSASA SASSTSTSAS PGSTTSPAST QRQRGRPAKR 
ATCTWCGEGK LPLQYVLPTQ TGKKEFCSET CIAEFRKAYS KGACTQCDNV IRDGAPNKEF 
CSIMCMNKHQ KKNCSTRHSG GSASGKGLAE SERKLLASGA PAPTGPFQYE SFHVFDWDAY 
LEETGSEAAP AKCFKQAQNP PNNDFKIGMK LEALDPRNVT STCIATVVGV LGSRLRLRLD 
GSDSQNDFWR LVDSTEIHAI GHCEKNGGML QPPLGFRMNA SSWPGYLCKI LNNAMVAPEE 
IFQPEPPEPE ENLFKVGQKL EAVDKKNPQL ICCATVDAIK DDQIHVTFDG WRGAFDYWCN 
YRSRDIFPAG WCARSCHPMQ PPGHKSRMDS SSSKQRCPRP RYTVVAESEA MVPASPATAH 
FHPNCKGGPF INNSKLPCMV TGPTYQTLAK LCLQEVLAAS TDTQQLSKLL FALEGDVHIV 
TAAGKNFTVK IPSPMRMKDD ESLAQFIETL CTTCRACANL ISLVHETEEC KKCANSRKRQ 
LTQSATPPSS PVLADKRNRQ SNSATTSPSE KIIKQELAVK SPVESKSKTS TNNGKEPASQ 
QNSNHSLNNN NNSASKSSNK VVIKSEPNGA NAQTSSTTQA LRKVRFQHHA NTNTNSSATN 
GNQDTSQTTH VSTSHCSSSS TSSSTSLAGG SANTSTIGKY LAPLVAEVHP EQANVKPSNS 
YYKSPTTLSS SASLPTSVST PFTGCQSASS TALAAGGVTA AKAATAPAGA AATAGASPSY 
TAITSPVSTP TSALANSHLR SQPIDWTIEE VIQYIESNDN SLAVHGDLFR KHEIDGKALL 
LLNSEMMMKY MGLKLGPALK ICNLVNKVNG RRNNLAL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Scm

Associated with

Other Information

The Drosophila polycomb group gene Sex comb on midleg (Scm) encodes a zinc finger protein with similarity to polyhomeotic protein. PubMed ID: 8625848

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

A domain shared by the polycomb group proteins Scm and ph mediates heterotypic and homotypic interactions. PubMed ID: 9343432

The Drosophila Corto protein interacts with Polycomb-group proteins and the GAGA factor. PubMed ID: 12771214

Requirement for sex comb on midleg protein interactions in Drosophila polycomb group repression. PubMed ID: 15280237

Phosphoproteome analysis of Drosophila melanogaster embryos. PubMed ID: 18327897

Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer. PubMed ID: 15905166