Details for: PGRP LB

Gene ID: 41379

Symbol: PGRP LB

Ensembl ID: FBgn0037906

Description: Peptidoglycan recognition protein LB

Associated with

  • Defense response to gram-positive bacterium
    (GO:0050830)
  • Extracellular region
    (GO:0005576)
  • Innate immune response
    (GO:0045087)
  • N-acetylmuramoyl-l-alanine amidase activity
    (GO:0008745)
  • Negative regulation of biosynthetic process of antibacterial peptides active against gram-negative bacteria
    (GO:0002814)
  • Negative regulation of peptidoglycan recognition protein signaling pathway
    (GO:0061060)
  • Peptidoglycan binding
    (GO:0042834)
  • Peptidoglycan catabolic process
    (GO:0009253)
  • Protein binding
    (GO:0005515)
  • Zinc ion binding
    (GO:0008270)

Other Information

Genular Protein ID: 1609430649

Symbol: PGPLB_DROME

Name: Peptidoglycan-recognition protein LB

UniProtKB Accession Codes:

Q8INK6 Q9VGN3

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 4 DNASU 1 EC 2 EMBL 6 EnsemblMetazoa 5 EvolutionaryTrace 1 ExpressionAtlas 1 FlyBase 1 GO 9 Gene3D 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PDB 7 PDBsum 5 PIRSF 1 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 5 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 11106397

Title: A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

PubMed ID: 11106397

DOI: 10.1073/pnas.97.25.13772

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 12032070

Title: The Toll and Imd pathways are the major regulators of the immune response in Drosophila.

PubMed ID: 12032070

DOI: 10.1093/emboj/21.11.2568

PubMed ID: 12845326

Title: Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster.

PubMed ID: 12845326

DOI: 10.1038/ni952

Sequence Information:

  • Length: 232
  • Mass: 25436
  • Checksum: 7BD18D4EC41F021E
  • Sequence:
    • MTALGLVLLS MMGYSQHMQQ ANLGDGVATA RLLSRSDWGA RLPKSVEHFQ GPAPYVIIHH 
SYMPAVCYST PDCMKSMRDM QDFHQLERGW NDIGYSFGIG GDGMIYTGRG FNVIGAHAPK 
YNDKSVGIVL IGDWRTELPP KQMLDAAKNL IAFGVFKGYI DPAYKLLGHR QVRDTECPGG 
RLFAEISSWP HFTHINDTEG VSSTTAPVVP HVHPQAAAPQ KPHQSPPAAP KV

Genular Protein ID: 2047737056

Symbol: A0A0B4K741_DROME

Name: N/A

UniProtKB Accession Codes:

A0A0B4K741

Database IDs:

AGR 1 ARBA 3 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 4 Gene3D 1 GenomeRNAi 1 InterPro 4 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 Pfam 1 PhylomeDB 1 Proteomes 2 RefSeq 1 SAM 1 SMART 4 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 255
  • Mass: 27756
  • Checksum: 60EDEB94903C10EC
  • Sequence:
    • MGDKVSGSVS TSGPTSLAIL MDSEQLEQQQ LATSCGYSQH MQQANLGDGV ATARLLSRSD 
WGARLPKSVE HFQGPAPYVI IHHSYMPAVC YSTPDCMKSM RDMQDFHQLE RGWNDIGYSF 
GIGGDGMIYT GRGFNVIGAH APKYNDKSVG IVLIGDWRTE LPPKQMLDAA KNLIAFGVFK 
GYIDPAYKLL GHRQVRDTEC PGGRLFAEIS SWPHFTHIND TEGVSSTTAP VVPHVHPQAA 
APQKPHQSPP AAPKV

Genular Protein ID: 1421086116

Symbol: A4V2P5_DROME

Name: N/A

UniProtKB Accession Codes:

A4V2P5

Database IDs:

AGR 1 ARBA 5 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 4 EnsemblMetazoa 4 ExpressionAtlas 1 FlyBase 2 GO 6 Gene3D 1 GenomeRNAi 1 HOGENOM 1 InterPro 5 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 1 Pfam 1 Proteomes 2 RefSeq 4 SAM 1 SMART 4 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 215
  • Mass: 23602
  • Checksum: AC661CAEBBE63215
  • Sequence:
    • MQQANLGDGV ATARLLSRSD WGARLPKSVE HFQGPAPYVI IHHSYMPAVC YSTPDCMKSM 
RDMQDFHQLE RGWNDIGYSF GIGGDGMIYT GRGFNVIGAH APKYNDKSVG IVLIGDWRTE 
LPPKQMLDAA KNLIAFGVFK GYIDPAYKLL GHRQVRDTEC PGGRLFAEIS SWPHFTHIND 
TEGVSSTTAP VVPHVHPQAA APQKPHQSPP AAPKV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.