Details for: ARSL

Gene ID: 415

Symbol: ARSL

Ensembl ID: ENSG00000157399

Description: arylsulfatase L

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 18.5300
    Cell Significance Index: -4.7000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 6.6091
    Cell Significance Index: -6.3100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 3.8981
    Cell Significance Index: 58.4100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.2594
    Cell Significance Index: 102.4100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.8645
    Cell Significance Index: 184.4500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.3232
    Cell Significance Index: 38.1300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.1757
    Cell Significance Index: 70.5800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.0998
    Cell Significance Index: 218.2600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9580
    Cell Significance Index: 155.8100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.9038
    Cell Significance Index: 14.5000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.8687
    Cell Significance Index: 18.5000
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.8427
    Cell Significance Index: 5.9300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7869
    Cell Significance Index: 710.5500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7861
    Cell Significance Index: 17.0300
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 0.6903
    Cell Significance Index: 2.6000
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.6816
    Cell Significance Index: 16.5100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.6785
    Cell Significance Index: 21.7300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.5999
    Cell Significance Index: 9.0400
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.5981
    Cell Significance Index: 4.7800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5887
    Cell Significance Index: 40.7100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.5464
    Cell Significance Index: 11.3400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4649
    Cell Significance Index: 321.5300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2476
    Cell Significance Index: 47.1200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.2389
    Cell Significance Index: 3.7900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1815
    Cell Significance Index: 31.0000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1612
    Cell Significance Index: 4.0300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.1062
    Cell Significance Index: 12.1700
  • Cell Name: epithelial cell of exocrine pancreas (CL1001433)
    Fold Change: 0.0996
    Cell Significance Index: 0.0500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.0982
    Cell Significance Index: 1.6600
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.0881
    Cell Significance Index: 0.6400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0763
    Cell Significance Index: 2.6800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0642
    Cell Significance Index: 23.0300
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 0.0572
    Cell Significance Index: 0.6200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0530
    Cell Significance Index: 6.8000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0397
    Cell Significance Index: 5.4500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0353
    Cell Significance Index: 7.0800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0222
    Cell Significance Index: 12.1500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.0217
    Cell Significance Index: 0.3200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0071
    Cell Significance Index: 5.2300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0031
    Cell Significance Index: 2.3600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0001
    Cell Significance Index: 0.1100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0003
    Cell Significance Index: -0.6200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0005
    Cell Significance Index: -0.7600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0027
    Cell Significance Index: -3.6400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0052
    Cell Significance Index: -3.8400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0058
    Cell Significance Index: -0.2700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0077
    Cell Significance Index: -4.3200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0084
    Cell Significance Index: -0.4200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0092
    Cell Significance Index: -5.7600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0098
    Cell Significance Index: -4.4500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0099
    Cell Significance Index: -6.2700
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0102
    Cell Significance Index: -0.4200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0105
    Cell Significance Index: -1.0700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0106
    Cell Significance Index: -0.1100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0115
    Cell Significance Index: -2.0700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0143
    Cell Significance Index: -4.1200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0154
    Cell Significance Index: -0.4300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0255
    Cell Significance Index: -5.3700
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: -0.0339
    Cell Significance Index: -0.2700
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0340
    Cell Significance Index: -0.2600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0372
    Cell Significance Index: -5.4100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0411
    Cell Significance Index: -5.3100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0438
    Cell Significance Index: -4.5700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0439
    Cell Significance Index: -5.4000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0445
    Cell Significance Index: -2.7300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0529
    Cell Significance Index: -2.3400
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.0580
    Cell Significance Index: -0.3600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0608
    Cell Significance Index: -4.6700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0610
    Cell Significance Index: -4.8300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0613
    Cell Significance Index: -2.3200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0659
    Cell Significance Index: -1.3800
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.0677
    Cell Significance Index: -0.9500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0679
    Cell Significance Index: -1.7500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0680
    Cell Significance Index: -1.8500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0708
    Cell Significance Index: -4.7600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0785
    Cell Significance Index: -4.9500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0792
    Cell Significance Index: -0.9000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0796
    Cell Significance Index: -2.7900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0814
    Cell Significance Index: -6.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0825
    Cell Significance Index: -4.6300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0870
    Cell Significance Index: -2.7700
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0922
    Cell Significance Index: -1.2300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0923
    Cell Significance Index: -4.8100
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0932
    Cell Significance Index: -0.6300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0936
    Cell Significance Index: -2.0500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0949
    Cell Significance Index: -6.1200
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.0967
    Cell Significance Index: -0.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0975
    Cell Significance Index: -5.1200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1026
    Cell Significance Index: -2.0600
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1039
    Cell Significance Index: -2.5900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1085
    Cell Significance Index: -1.8600
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: -0.1137
    Cell Significance Index: -0.6600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1174
    Cell Significance Index: -6.1000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1191
    Cell Significance Index: -3.9000
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.1221
    Cell Significance Index: -1.7500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1229
    Cell Significance Index: -3.6200
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.1241
    Cell Significance Index: -0.6500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1244
    Cell Significance Index: -5.8500
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.1275
    Cell Significance Index: -1.6700
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.1287
    Cell Significance Index: -1.7800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key characteristics** * Arylsulfatase L is a lysosomal enzyme that hydrolyzes arylsulfates, a type of sulfate ester found in glycosphingolipids. * The enzyme is characterized by its ability to remove sulfate groups from glycosphingolipids, resulting in the production of aglycones and sulfate-containing lipids. * ARSL is a metal-dependent enzyme, requiring zinc ions for its catalytic activity. * The enzyme is highly specific, with a high affinity for its substrate and low affinity for other molecules. * ARSL is involved in various cellular processes, including protein modification, lipid metabolism, and cellular signaling. **Pathways and functions** * Glycosphingolipid catabolism: ARSL plays a crucial role in the degradation of glycosphingolipids, which are essential components of the cell membrane. * Glycosphingolipid metabolism: ARSL is involved in the regulation of glycosphingolipid metabolism, which is essential for maintaining cellular homeostasis. * Arylsulfatase activity: ARSL is a member of the arylsulfatase family, which is involved in various cellular processes, including protein modification and lipid metabolism. * Post-translational protein modification: ARSL is involved in the modification of proteins, particularly those involved in cellular signaling. * Metal ion binding: ARSL requires zinc ions for its catalytic activity, highlighting the importance of metal ion binding in enzyme function. * Hydroxylation and hypusinylation: ARSL is involved in the regulation of hydroxylation and hypusinylation reactions, which are essential for protein modification and cellular signaling. **Clinical significance** * ARSL deficiency: Mutations in the ARSL gene have been associated with a rare genetic disorder characterized by intellectual disability, seizures, and developmental delays. * Cancer: ARSL has been implicated in cancer development and progression, particularly in the context of glycosphingolipid metabolism. * Neurological disorders: ARSL has been implicated in various neurological disorders, including Alzheimer's disease and Parkinson's disease, due to its role in glycosphingolipid metabolism and protein modification. * Inflammatory diseases: ARSL has been implicated in inflammatory diseases, such as rheumatoid arthritis and multiple sclerosis, due to its role in glycosphingolipid metabolism and cellular signaling. In conclusion, ARSL is a critical enzyme involved in glycosphingolipid metabolism and protein modification. Its dysregulation has been implicated in various diseases, including genetic disorders, cancer, and neurological disorders. Further research is needed to fully understand the role of ARSL in human disease and to develop therapeutic strategies to target this enzyme.

Genular Protein ID: 1941511701

Symbol: ARSL_HUMAN

Name: Arylsulfatase L

UniProtKB Accession Codes:

P51690 Q53FT2 Q53FU8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 11 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 2 Rhea 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7720070

Title: A cluster of sulfatase genes on Xp22.3: mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy.

PubMed ID: 7720070

DOI: 10.1016/0092-8674(95)90367-4

PubMed ID: 9497243

Title: Biochemical characterization of arylsulfatase E and functional analysis of mutations found in patients with X-linked chondrodysplasia punctata.

PubMed ID: 9497243

DOI: 10.1086/301746

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 9409863

Title: X-linked recessive chondrodysplasia punctata due to a new point mutation of the ARSE gene.

PubMed ID: 9409863

DOI: 10.1002/(sici)1096-8628(19971212)73:2<139::aid-ajmg7>3.0.co;2-p

PubMed ID: 12567415

Title: X-linked recessive chondrodysplasia punctata: spectrum of arylsulfatase E gene mutations and expanded clinical variability.

PubMed ID: 12567415

DOI: 10.1002/ajmg.a.10950

Sequence Information:

  • Length: 589
  • Mass: 65669
  • Checksum: 37A941EF4A44027A
  • Sequence:
    • MLHLHHSCLC FRSWLPAMLA VLLSLAPSAS SDISASRPNI LLLMADDLGI GDIGCYGNNT 
MRTPNIDRLA EDGVKLTQHI SAASLCTPSR AAFLTGRYPV RSGMVSSIGY RVLQWTGASG 
GLPTNETTFA KILKEKGYAT GLIGKWHLGL NCESASDHCH HPLHHGFDHF YGMPFSLMGD 
CARWELSEKR VNLEQKLNFL FQVLALVALT LVAGKLTHLI PVSWMPVIWS ALSAVLLLAS 
SYFVGALIVH ADCFLMRNHT ITEQPMCFQR TTPLILQEVA SFLKRNKHGP FLLFVSFLHV 
HIPLITMENF LGKSLHGLYG DNVEEMDWMV GRILDTLDVE GLSNSTLIYF TSDHGGSLEN 
QLGNTQYGGW NGIYKGGKGM GGWEGGIRVP GIFRWPGVLP AGRVIGEPTS LMDVFPTVVR 
LAGGEVPQDR VIDGQDLLPL LLGTAQHSDH EFLMHYCERF LHAARWHQRD RGTMWKVHFV 
TPVFQPEGAG ACYGRKVCPC FGEKVVHHDP PLLFDLSRDP SETHILTPAS EPVFYQVMER 
VQQAVWEHQR TLSPVPLQLD RLGNIWRPWL QPCCGPFPLC WCLREDDPQ

Genular Protein ID: 3477520068

Symbol: A0A804HJF6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A804HJF6

Database IDs:

ARBA 3 Bgee 1 CTD 1 ChEBI 1 DisGeNET 1 EMBL 1 Ensembl 3 GO 1 Gene3D 2 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 402
  • Mass: 44366
  • Checksum: B4BDC050822ACD33
  • Sequence:
    • MLHLHHSCLC FRSWLPAMLA VLLSLAPSAS SDISASRPNI LLLMADDLGI GDIGCYGNNT 
MRTPNIDRLA EDGVKLTQHI SAASLCTPSR AAFLTGRYPV RSGMVSSIGY RVLQWTGASG 
GLPTNETTFA KILKEKGYAT GLIGRILDTL DVEGLSNSTL IYFTSDHGGS LENQLGNTQY 
GGWNGIYKGG KGMGGWEGGI RVPGIFRWPG VLPAGRVIGE PTSLMDVFPT VVRLAGGEVP 
QDRVIDGQDL LPLLLGTAQH SDHEFLMHYC ERFLHAARWH QRDRGTMWKV HFVTPVFQPE 
GAGACYGRKV CPCFGEKVVH HDPPLLFDLS RDPSETHILT PASEPVFYQV MERVQQAVWE 
HQRTLSPVPL QLDRLGNIWR PWLQPCCGPF PLCWCLREDD PQ

Genular Protein ID: 570427576

Symbol: A0A5F9ZHX8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A5F9ZHX8

Database IDs:

ARBA 3 Antibodypedia 1 Bgee 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 4 GO 3 Gene3D 3 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 535
  • Mass: 60044
  • Checksum: F5BB56414DF263C7
  • Sequence:
    • MLHLHHSWTP NIDRLAEDGV KLTQHISAAS LCTPSRAAFL TGRYPVRSGM VSSIGYRVLQ 
WTGASGGLPT NETTFAKILK EKGYATGLIG KWHLGLNCES ASDHCHHPLH HGFDHFYGMP 
FSLMGDCARW ELSEKRVNLE QKLNFLFQVL ALVALTLVAG KLTHLIPVSW MPVIWSALSA 
VLLLASSYFV GALIVHADCF LMRNHTITEQ PMCFQRTTPL ILQEVASFLK RNKHGPFLLF 
VSFLHVHIPL ITMENFLGKS LHGLYGDNVE EMDWMVGRIL DTLDVEGLSN STLIYFTSDH 
GGSLENQLGN TQYGGWNGIY KGGKGMGGWE GGIRVPGIFR WPGVLPAGRV IGEPTSLMDV 
FPTVVRLAGG EVPQDRVIDG QDLLPLLLGT AQHSDHEFLM HYCERFLHAA RWHQRDRGTM 
WKVHFVTPVF QPEGAGACYG RKVCPCFGEK VVHHDPPLLF DLSRDPSETH ILTPASEPVF 
YQVMERVQQA VWEHQRTLSP VPLQLDRLGN IWRPWLQPCC GPFPLCWCLR EDDPQ

Genular Protein ID: 295706746

Symbol: F5H324_HUMAN

Name: N/A

UniProtKB Accession Codes:

F5H324

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 3 HGNC 1 HOGENOM 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 544
  • Mass: 61077
  • Checksum: 3FC4D0B5B44DB6E9
  • Sequence:
    • MSGSRERDNM LHLHHSWTPN IDRLAEDGVK LTQHISAASL CTPSRAAFLT GRYPVRSGMV 
SSIGYRVLQW TGASGGLPTN ETTFAKILKE KGYATGLIGK WHLGLNCESA SDHCHHPLHH 
GFDHFYGMPF SLMGDCARWE LSEKRVNLEQ KLNFLFQVLA LVALTLVAGK LTHLIPVSWM 
PVIWSALSAV LLLASSYFVG ALIVHADCFL MRNHTITEQP MCFQRTTPLI LQEVASFLKR 
NKHGPFLLFV SFLHVHIPLI TMENFLGKSL HGLYGDNVEE MDWMVGRILD TLDVEGLSNS 
TLIYFTSDHG GSLENQLGNT QYGGWNGIYK GGKGMGGWEG GIRVPGIFRW PGVLPAGRVI 
GEPTSLMDVF PTVVRLAGGE VPQDRVIDGQ DLLPLLLGTA QHSDHEFLMH YCERFLHAAR 
WHQRDRGTMW KVHFVTPVFQ PEGAGACYGR KVCPCFGEKV VHHDPPLLFD LSRDPSETHI 
LTPASEPVFY QVMERVQQAV WEHQRTLSPV PLQLDRLGNI WRPWLQPCCG PFPLCWCLRE 
DDPQ

Genular Protein ID: 3587842175

Symbol: B7Z1M0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z1M0

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 3 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 RefSeq 2 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 544
  • Mass: 61017
  • Checksum: 97B4D9CA183DB03A
  • Sequence:
    • MSGSRERDNM LHLHHSWTPN IDRLAEDGVK LTQHISAASL CTPSRAAFLT GRYPVRSGMV 
SSIGYRVLQW TGASGGLPTN ETTFAKILKE KGYATGLIGK WHLGLNCESA SDHCHHPLHH 
GFDHFYGMPF SLMGDCARWE LSEKRVNLEQ KLNFLFQVLA LVALTLVAGK LTHLIPVSWM 
PVIWSALSAV LLLASSYFVG ALIVHADCFL MRNHTITEQP MCFQRTTPLI LQEVASSLKR 
NKHGPFLLFV SFLHVHIPLI TMENFLGKSL HGLYGDNVEE MDWMVGRILD TLDVEGLSNS 
TLIYFTSDHG GSLENQLGNT QYGGWNGIYK GGKGMGGWEG GIRVPGIFRW PGVLPAGRVI 
GEPTSLMDVF PTVVRLAGGE VPQDRVIDGQ DLLPLLLGTA QHSDHEFLMH YCERFLHAAR 
WHQRDRGTMW KVHFVTPVFQ PEGAGACYGR KVCPCFGEKV VHHDPPLLFD LSRDPSETHI 
LTPASEPVFY QVMERVQQAV WEHQRTLSPV PLQLDRLGNI WRPWLQPCCG PFPLCWCLRE 
DDPQ

Genular Protein ID: 3724750100

Symbol: A1L484_HUMAN

Name: N/A

UniProtKB Accession Codes:

A1L484

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 3 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 RefSeq 2 SAM 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 589
  • Mass: 65655
  • Checksum: 32F4F8C18544027A
  • Sequence:
    • MLHLHHSCLC FRSWLPAMLA VLLSLAPSAS SDISASRPNI LLLMADDLGI GDVGCYGNNT 
MRTPNIDRLA EDGVKLTQHI SAASLCTPSR AAFLTGRYPV RSGMVSSIGY RVLQWTGASG 
GLPTNETTFA KILKEKGYAT GLIGKWHLGL NCESASDHCH HPLHHGFDHF YGMPFSLMGD 
CARWELSEKR VNLEQKLNFL FQVLALVALT LVAGKLTHLI PVSWMPVIWS ALSAVLLLAS 
SYFVGALIVH ADCFLMRNHT ITEQPMCFQR TTPLILQEVA SFLKRNKHGP FLLFVSFLHV 
HIPLITMENF LGKSLHGLYG DNVEEMDWMV GRILDTLDVE GLSNSTLIYF TSDHGGSLEN 
QLGNTQYGGW NGIYKGGKGM GGWEGGIRVP GIFRWPGVLP AGRVIGEPTS LMDVFPTVVR 
LAGGEVPQDR VIDGQDLLPL LLGTAQHSDH EFLMHYCERF LHAARWHQRD RGTMWKVHFV 
TPVFQPEGAG ACYGRKVCPC FGEKVVHHDP PLLFDLSRDP SETHILTPAS EPVFYQVMER 
VQQAVWEHQR TLSPVPLQLD RLGNIWRPWL QPCCGPFPLC WCLREDDPQ

Genular Protein ID: 2774424673

Symbol: B7Z6V4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z6V4

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 3 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 614
  • Mass: 68158
  • Checksum: DFF25BC5B3930E17
  • Sequence:
    • MRPVINRCAP GSLDLMLPQA ASEGIVFHSL QISLCFRSWL PAMLAVLLSL APSASSDISA 
SRPNILLLMA DDLGIGDIGC YGNNTMRTPN IDRLAEAGVK LTQHISAASL CTPSRAAFLT 
GRYPVRSGMV SSIGYRVLQW TGASGGLPTN ETTFAKILKG KGYATGLIGK WHLGLNCESA 
SDHCHHPLHH GFDHFYGMPF SLMGDCARWE LSEKRVNLEQ KLNFLFQVLA LVALTLVAGK 
LTHLIPVSWM PVIWSALSAV LLLASSYFVG ALIVHADCFL MRNHTITEQP MCFQRTTPLI 
LQEVASFLKR NKHGPFLLFV SFLHVHIPLI TMENFLGKSL HGLYGDNVEE MDWMVGRILD 
TLDVEGLSNS TLIYFTSDHG GSLENQLGNT QYGGWNGIYK GGKGMGGWEG GIRVPGIFRW 
PGVLPAGRVI GEPTSLMDVF PTVVRLAGSE VPQDRVIDGQ DLLPLLLGTA QHSDHEFLMH 
YCERFLHAAR WHQRDRGTMW KVHFVTPVFQ PEGAGACYGR KVCPCFGEKV VHHDPPLLFD 
LSRDPSETHI LTPASEPVFY QVMERVQQAV WEHQRTLSPV PLQLDRLGNI WRPWLQPCCG 
PFPLCWCLRE DDPQ

Genular Protein ID: 1048762109

Symbol: F5GYY5_HUMAN

Name: N/A

UniProtKB Accession Codes:

F5GYY5

Database IDs:

ARBA 3 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 5 GO 3 Gene3D 3 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 2 SAM 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 614
  • Mass: 68244
  • Checksum: 33DCDE43C1D22E9D
  • Sequence:
    • MRPVINRCAP GSLDLMLPQA ASEGIVFHSL QISLCFRSWL PAMLAVLLSL APSASSDISA 
SRPNILLLMA DDLGIGDIGC YGNNTMRTPN IDRLAEDGVK LTQHISAASL CTPSRAAFLT 
GRYPVRSGMV SSIGYRVLQW TGASGGLPTN ETTFAKILKE KGYATGLIGK WHLGLNCESA 
SDHCHHPLHH GFDHFYGMPF SLMGDCARWE LSEKRVNLEQ KLNFLFQVLA LVALTLVAGK 
LTHLIPVSWM PVIWSALSAV LLLASSYFVG ALIVHADCFL MRNHTITEQP MCFQRTTPLI 
LQEVASFLKR NKHGPFLLFV SFLHVHIPLI TMENFLGKSL HGLYGDNVEE MDWMVGRILD 
TLDVEGLSNS TLIYFTSDHG GSLENQLGNT QYGGWNGIYK GGKGMGGWEG GIRVPGIFRW 
PGVLPAGRVI GEPTSLMDVF PTVVRLAGGE VPQDRVIDGQ DLLPLLLGTA QHSDHEFLMH 
YCERFLHAAR WHQRDRGTMW KVHFVTPVFQ PEGAGACYGR KVCPCFGEKV VHHDPPLLFD 
LSRDPSETHI LTPASEPVFY QVMERVQQAV WEHQRTLSPV PLQLDRLGNI WRPWLQPCCG 
PFPLCWCLRE DDPQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.