Details for: HtrA2

Gene ID: 41756

Symbol: HtrA2

Ensembl ID: FBgn0038233

Description: HTRA2-related serine protease

Associated with

Other Information

Genular Protein ID: 1206903990

Symbol: HTRA2_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VFJ3

Database IDs:

AGR 1 AlphaFoldDB 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 EC 2 EMBL 6 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 2 GO 16 Gene3D 2 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MEROPS 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 Reactome 1 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 17397804

Title: Evolution of mitochondrial cell death pathway: Proapoptotic role of HtrA2/Omi in Drosophila.

PubMed ID: 17397804

DOI: 10.1016/j.bbrc.2007.03.079

PubMed ID: 17557079

Title: Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease.

PubMed ID: 17557079

DOI: 10.1038/sj.emboj.7601745

PubMed ID: 18259196

Title: The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila.

PubMed ID: 18259196

DOI: 10.1038/cdd.2008.19

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 19048081

Title: Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin.

PubMed ID: 19048081

DOI: 10.1242/dmm.000109

Sequence Information:

  • Length: 422
  • Mass: 46000
  • Checksum: 7BDD72E4CA86B5D5
  • Sequence:
    • MALRGSHRLE VIFKRCIASP VLHSHAANRR SSQLAIKEGD PNSNGNSGQY QQNGEQKEKG 
WRRLVRFFVP FSLGAVVSAA IIQREDLTPT IAASKMTGRR RDFNFIADVV AGCADSVVYI 
EIKDTRHFDY FSGQPITASN GSGFIIEQNG LILTNAHVVI NKPHTMVQVR LSDGRTFPAT 
IEDVDQTSDL ATLRIQVNNL SVMRLGKSST LRSGEWVVAL GSPLALSNTV TAGVISSTQR 
ASQELGLRNR DINYLQTDAA ITFGNSGGPL VNLDGEAIGV NSMKVTAGIS FAIPIDYVKV 
FLERAAEKRK KGSAYKTGYP VKRYMGITML TLTPDILFEL KSRSQNMPSN LTHGVLVWKV 
IVGSPAHSGG LQPGDIVTHI NKKEIKNSSD VYDALADNSK TLDIVILRGV KQMHVTITPE 
DP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.