Details for: MED17

Gene ID: 42175

Symbol: MED17

Ensembl ID: FBgn0038578

Description: Mediator complex subunit 17

Associated with

  • Epigenetic regulation by wdr5-containing histone modifying complexes
    (R-DME-9917777)
  • Epigenetic regulation of adipogenesis genes by mll3 and mll4 complexes
    (R-DME-9851695)
  • Epigenetic regulation of gene expression
    (R-DME-212165)
  • Epigenetic regulation of gene expression by mll3 and mll4 complexes
    (R-DME-9818564)
  • Gene expression (transcription)
    (R-DME-74160)
  • Mll4 and mll3 complexes regulate expression of pparg target genes in adipogenesis and hepatic steatosis
    (R-DME-9841922)
  • Core mediator complex
    (GO:0070847)
  • Dna-binding transcription factor binding
    (GO:0140297)
  • Mediator complex
    (GO:0016592)
  • Nucleus
    (GO:0005634)
  • Pericentric heterochromatin
    (GO:0005721)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Regulation of transcription initiation by rna polymerase ii
    (GO:0060260)
  • Sex comb development
    (GO:0045498)
  • Transcription coactivator activity
    (GO:0003713)
  • Transcription coregulator activity
    (GO:0003712)

Other Information

Genular Protein ID: 2353527531

Symbol: MED17_DROME

Name: Mediator of RNA polymerase II transcription subunit 17

UniProtKB Accession Codes:

Q9VEC1

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ComplexPortal 1 DIP 1 DNASU 1 EMBL 4 EnsemblMetazoa 1 FlyBase 1 GO 10 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 PhylomeDB 1 Proteomes 1 RefSeq 1 SMR 1 STRING 1 SignaLink 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 11090137

Title: Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification.

PubMed ID: 11090137

DOI: 10.1101/gad.17900

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 11511356

Title: Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock.

PubMed ID: 11511356

DOI: 10.1016/s1097-2765(01)00296-9

PubMed ID: 11259581

Title: Drosophila Mediator complex is broadly utilized by diverse gene-specific transcription factors at different types of core promoters.

PubMed ID: 11259581

DOI: 10.1128/mcb.21.7.2312-2323.2001

PubMed ID: 12021283

Title: Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

PubMed ID: 12021283

DOI: 10.1074/jbc.m204144200

PubMed ID: 16751183

Title: Coactivator cross-talk specifies transcriptional output.

PubMed ID: 16751183

DOI: 10.1101/gad.1418806

Sequence Information:

  • Length: 642
  • Mass: 71557
  • Checksum: 9EBD4E084788AF58
  • Sequence:
    • MSNSVNISVE TTCENQIREI GYDGTELYQP PPTLSESLAK CAARIDFSKT SLDDLKKEEK 
SAAAAADEDK DATQFQESLW PWDAVRNKLK DALTEICVLS DVISIAKDKR YLVLDPLLEE 
ADDTKPIVQV YSRKKAISQA AQVLLSGAER LRNAHSEQRN RNVSDFHIEL LRLRQNWRLK 
KVSNAIIGDL SYRTAGSKFG MSGTFEVTKA EETGDEDTAS SSNSSSSVSG NNGMQLKASS 
ALRVIVPAEL QGVAYIKVIT QKDQEDLCTA QLNLMGHGPN ITAQVGVWQK TLEFAQNVLF 
CKELFAQLAR EAIQLQAPIP HVVIGNQIRA TLLPNIQLII SLCHSTTFDS SQPAPINDHD 
HVLEHSLHQL LREVHYKNSH HPFPHPASAP LGPTKKRMLA GPMAADRETL LDMTKSQTIL 
EQIIAQAQHI FMRKRTQYVL DTLARDVKDP QIVSHWNAMN SPTMSCVKIN IVTHGYDAIG 
RTSLVIHVKE RSLKCICRDG RVMRLSYEPQ ELRDLILCQI NSHQISCLIS LARCMSWTVL 
SNSNHLGIGK VEPLGNASSC LLASPNSDRM IAVQIRCDPQ IDVKVYIARS PRQDFFPSPL 
VPEKLWENLG GTFKEVRFDK IEGKSFLNKM EFLMASLTSN TA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.