Details for: slmb

Gene ID: 42504

Symbol: slmb

Ensembl ID: FBgn0283468

Description: supernumerary limbs

Associated with

  • Beta-catenin destruction complex binding
    (GO:1904713)
  • Chorion-containing eggshell formation
    (GO:0007304)
  • Circadian rhythm
    (GO:0007623)
  • Cytoplasm
    (GO:0005737)
  • Dorsal appendage formation
    (GO:0046843)
  • Establishment of epithelial cell polarity
    (GO:0090162)
  • Follicle cell of egg chamber development
    (GO:0030707)
  • Follicle cell of egg chamber stalk formation
    (GO:0030713)
  • Germarium-derived egg chamber formation
    (GO:0007293)
  • Germarium-derived female germ-line cyst encapsulation
    (GO:0030708)
  • Germarium-derived female germ-line cyst formation
    (GO:0030727)
  • Locomotor rhythm
    (GO:0045475)
  • Molecular adaptor activity
    (GO:0060090)
  • Negative regulation of antimicrobial peptide production
    (GO:0002785)
  • Negative regulation of apoptotic process
    (GO:0043066)
  • Negative regulation of canonical wnt signaling pathway
    (GO:0090090)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of glial cell proliferation
    (GO:0060253)
  • Negative regulation of hippo signaling
    (GO:0035331)
  • Negative regulation of insulin receptor signaling pathway
    (GO:0046627)
  • Negative regulation of nurse cell apoptotic process
    (GO:0045849)
  • Negative regulation of peptidoglycan recognition protein signaling pathway
    (GO:0061060)
  • Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051898)
  • Negative regulation of smoothened signaling pathway
    (GO:0045879)
  • Nucleus
    (GO:0005634)
  • Oocyte axis specification
    (GO:0007309)
  • Oocyte localization involved in germarium-derived egg chamber formation
    (GO:0030720)
  • Phosphoprotein binding
    (GO:0051219)
  • Positive regulation of border follicle cell migration
    (GO:1903688)
  • Positive regulation of neuron remodeling
    (GO:1904801)
  • Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
    (GO:0032436)
  • Positive regulation of protein catabolic process
    (GO:0045732)
  • Positive regulation of synaptonemal complex assembly
    (GO:1905088)
  • Positive regulation of toll signaling pathway
    (GO:0045752)
  • Protein dimerization activity
    (GO:0046983)
  • Protein k11-linked ubiquitination
    (GO:0070979)
  • Protein polyubiquitination
    (GO:0000209)
  • Protein ubiquitination
    (GO:0016567)
  • Proteolysis
    (GO:0006508)
  • Regulation of cell cycle
    (GO:0051726)
  • Regulation of centriole replication
    (GO:0046599)
  • Regulation of chromosome condensation
    (GO:0060623)
  • Regulation of establishment of cell polarity
    (GO:2000114)
  • Regulation of mitotic nuclear division
    (GO:0007088)
  • Regulation of proteasomal protein catabolic process
    (GO:0061136)
  • Scf-dependent proteasomal ubiquitin-dependent protein catabolic process
    (GO:0031146)
  • Scf ubiquitin ligase complex
    (GO:0019005)
  • Ubiquitin ligase-substrate adaptor activity
    (GO:1990756)

Other Information

Genular Protein ID: 4066086702

Symbol: Q9VDE3_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VDE3

Database IDs:

AGR 1 ARBA 2 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 EMBL 10 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 2 GO 31 Gene3D 3 GeneTree 1 GenomeRNAi 1 HOGENOM 1 IntAct 1 InterPro 8 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 PaxDb 1 Pfam 3 Proteomes 2 RefSeq 2 SMART 3 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10781936

Title: Drosophila null slimb clones transiently deregulate Hedgehog-independent transcription of wingless in all limb discs, and induce decapentaplegic transcription linked to imaginal disc regeneration.

PubMed ID: 10781936

DOI: 10.1016/S0925-4773(00)00256-2

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 510
  • Mass: 58952
  • Checksum: F4D5DF126F58A012
  • Sequence:
    • MMKMETDKIM DETNSNAQAF TTTMLYDPVR KKDSSPTYQT ERELCFQYFT QWSESGQVDF 
VEHLLSRMCH YQHGQINAYL KPMLQRDFIT LLPIKGLDHI AENILSYLDA ESLKSSELVC 
KEWLRVISEG MLWKKLIERK VRTDSLWRGL AERRNWMQYL FKPRPGQTQR PHSFHRELFP 
KIMNDIDSIE NNWRTGRHML RRINCRSENS KGVYCLQYDD GKIVSGLRDN TIKIWDRTDL 
QCVKTLMGHT GSVLCLQYDD KVIISGSSDS TVRVWDVNTG EMVNTLIHHC EAVLHLRFNN 
GMMVTCSKDR SIAVWDMTSP SEITLRRVLV GHRAAVNVVD FDEKYIVSAS GDRTIKVWST 
SSCEFVRTLN GHKRGIACLQ YRDRLVVSGS SDNSIRLWDI ECGACLRVLE GHEELVRCIR 
FDTKRIVSGA YDGKIKVWDL VAALDPRAAS NTLCLNTLVE HTGRVFRLQF DEFQIVSSSH 
DDTILIWDFL NFTPNENKTG RTPSPALMEH

Genular Protein ID: 272158339

Symbol: A0A0B4KHK1_DROME

Name: N/A

UniProtKB Accession Codes:

A0A0B4KHK1

Database IDs:

AGR 1 ARBA 2 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ComplexPortal 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 48 Gene3D 3 GeneTree 1 GenomeRNAi 1 InParanoid 1 InterPro 8 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 Pfam 3 PhylomeDB 1 Proteomes 2 RefSeq 1 SAM 1 SMART 3 STRING 1 SUPFAM 2 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 597
  • Mass: 68620
  • Checksum: 645BBD335A55B3CF
  • Sequence:
    • MMKMETDKIM DETNSNAQAF TTTMLYDPVR KKDSSPTYQT ERELCFQYFT QWSESGQVDF 
VEHLLSRMCH YQHGQINAYL KPMLQRDFIT LLPIKGLDHI AENILSYLDA ESLKSSELVC 
KEWLRVISEG MLWKKLIERK VRTDSLWRGL AERRNWMQYL FKPRPGQTQR PHSFHRELFP 
KIMNDIDSIE NNWRTGRHML RRINCRSENS KGVYCLQYDD GKIVSGLRDN TIKIWDRTDL 
QCVKTLMGHT GSVLCLQYDD KVIISGSSDS TVRVWDVNTG EMVNTLIHHC EAVLHLRFNN 
GMMVTCSKDR SIAVWDMTSP SEITLRRVLV GHRAAVNVVD FDEKYIVSAS GDRTIKVWST 
SSCEFVRTLN GHKRGIACLQ YRDRLVVSGS SDNSIRLWDI ECGACLRVLE GHEELVRCIR 
FDTKRIVSGA YDGKIKVWDL VAALDPRAAS NTLCLNTLVE HTGRVFRLQF DEFQIVSSSH 
DDTILIWDFL NFTPNENKTG RTPSPALMEH XHFVQRQLRE LHLQSSSEGE EDDDADEDDE 
DDFEEEDSRN DAGAFMGGYV RHRDAGGSGS VTGSGSDPES DDLDFDIDVE NINDYDE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.