Details for: InR

Gene ID: 42549

Symbol: InR

Ensembl ID: FBgn0283499

Description: Insulin-like receptor

Associated with

Other Information

Genular Protein ID: 2923307239

Symbol: INSR_DROME

Name: Insulin-like receptor

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7628438

Title: The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential.

PubMed ID: 7628438

DOI: 10.1002/j.1460-2075.1995.tb07343.x

PubMed ID: 7876183

Title: The Drosophila insulin receptor contains a novel carboxyl-terminal extension likely to play an important role in signal transduction.

PubMed ID: 7876183

DOI: 10.1074/jbc.270.9.4236

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 3099787

Title: Cloning of a Drosophila cDNA encoding a polypeptide similar to the human insulin receptor precursor.

PubMed ID: 3099787

DOI: 10.1016/s0006-291x(86)80197-8

PubMed ID: 3014506

Title: Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody.

PubMed ID: 3014506

DOI: 10.1073/pnas.83.13.4710

PubMed ID: 2454394

Title: Tissue localization of Drosophila melanogaster insulin receptor transcripts during development.

PubMed ID: 2454394

DOI: 10.1128/mcb.8.4.1638-1647.1988

PubMed ID: 8603594

Title: The Drosophila insulin receptor is required for normal growth.

PubMed ID: 8603594

DOI: 10.1210/endo.137.3.8603594

PubMed ID: 10455177

Title: The carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival.

PubMed ID: 10455177

DOI: 10.1074/jbc.274.35.24987

PubMed ID: 11250149

Title: An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control.

PubMed ID: 11250149

DOI: 10.1016/s0960-9822(01)00068-9

PubMed ID: 11292875

Title: A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function.

PubMed ID: 11292875

DOI: 10.1126/science.1057987

PubMed ID: 12702880

Title: Axons guided by insulin receptor in Drosophila visual system.

PubMed ID: 12702880

DOI: 10.1126/science.1081203

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21707536

Title: Dock/Nck facilitates PTP61F/PTP1B regulation of insulin signalling.

PubMed ID: 21707536

DOI: 10.1042/bj20110799

Sequence Information:

  • Length: 2144
  • Mass: 239776
  • Checksum: C4A8ECB08C70523A
  • Sequence:
  • MFNMPRGVTK SKSKRGKIKM ENDMAAAATT TACTLGHICV LCRQEMLLDT CCCRQAVEAV 
    DSPASSEEAY SSSNSSSCQA SSEISAEEVW FLSHDDIVLC RRPKFDEVET TGKKRDVKCS 
    GHQCSNECDD GSTKNNRQQR ENFNIFSNCH NILRTLQSLL LLMFNCGIFN KRRRRQHQQQ 
    HHHHYQHHHQ QHHQQHHQRQ QANVSYTKFL LLLQTLAAAT TRLSLSPKNY KQQQQLQHNQ 
    QLPRATPQQK QQEKDRHKCF HYKHNYSYSP GISLLLFILL ANTLAIQAVV LPAHQQHLLH 
    NDIADGLDKT ALSVSGTQSR WTRSESNPTM RLSQNVKPCK SMDIRNMVSH FNQLENCTVI 
    EGFLLIDLIN DASPLNRSFP KLTEVTDYII IYRVTGLHSL SKIFPNLSVI RGNKLFDGYA 
    LVVYSNFDLM DLGLHKLRSI TRGGVRIEKN HKLCYDRTID WLEILAENET QLVVLTENGK 
    EKECRLSKCP GEIRIEEGHD TTAIEGELNA SCQLHNNRRL CWNSKLCQTK CPEKCRNNCI 
    DEHTCCSQDC LGGCVIDKNG NESCISCRNV SFNNICMDSC PKGYYQFDSR CVTANECITL 
    TKFETNSVYS GIPYNGQCIT HCPTGYQKSE NKRMCEPCPG GKCDKECSSG LIDSLERARE 
    FHGCTIITGT EPLTISIKRE SGAHVMDELK YGLAAVHKIQ SSLMVHLTYG LKSLKFFQSL 
    TEISGDPPMD ADKYALYVLD NRDLDELWGP NQTVFIRKGG VFFHFNPKLC VSTINQLLPM 
    LASKPKFFEK SDVGADSNGN RGSCGTAVLN VTLQSVGANS AMLNVTTKVE IGEPQKPSNA 
    TIVFKDPRAF IGFVFYHMID PYGNSTKSSD DPCDDRWKVS SPEKSGVMVL SNLIPYTNYS 
    YYVRTMAISS ELTNAESDVK NFRTNPGRPS KVTEVVATAI SDSKINVTWS YLDKPYGVLT 
    RYFIKAKLIN RPTRNNNRDY CTEPLVKAME NDLPATTPTK KISDPLAGDC KCVEGSKKTS 
    SQEYDDRKVQ AGMEFENALQ NFIFVPNIRK SKNGSSDKSD GAEGAALDSN AIPNGGATNP 
    SRRRRDVALE PELDDVEGSV LLRHVRSITD DTDAFFEKDD ENTYKDEEDL SSNKQFYEVF 
    AKELPPNQTH FVFEKLRHFT RYAIFVVACR EEIPSEKLRD TSFKKSLCSD YDTVFQTTKR 
    KKFADIVMDL KVDLEHANNT ESPVRVRWTP PVDPNGEIVT YEVAYKLQKP DQVEEKKCIP 
    AADFNQTAGY LIKLNEGLYS FRVRANSIAG YGDFTEVEHI KVEPPPSYAK VFFWLLGIGL 
    AFLIVSLFGY VCYLHKRKVP SNDLHMNTEV NPFYASMQYI PDDWEVLREN IIQLAPLGQG 
    SFGMVYEGIL KSFPPNGVDR ECAIKTVNEN ATDRERTNFL SEASVMKEFD TYHVVRLLGV 
    CSRGQPALVV MELMKKGDLK SYLRAHRPEE RDEAMMTYLN RIGVTGNVQP PTYGRIYQMA 
    IEIADGMAYL AAKKFVHRDL AARNCMVADD LTVKIGDFGM TRDIYETDYY RKGTKGLLPV 
    RWMPPESLRD GVYSSASDVF SFGVVLWEMA TLAAQPYQGL SNEQVLRYVI DGGVMERPEN 
    CPDFLHKLMQ RCWHHRSSAR PSFLDIIAYL EPQCPNSQFK EVSFYHSEAG LQHREKERKE 
    RNQLDAFAAV PLDQDLQDRE QQEDATTPLR MGDYQQNSSL DQPPESPIAM VDDQGSHLPF 
    SLPSGFIASS TPDGQTVMAT AFQNIPAAQG DISATYVVPD ADALDGDRGY EIYDPSPKCA 
    ELPTSRSGST GGGKLSGEQH LLPRKGRQPT IMSSSMPDDV IGGSSLQPST ASAGSSNASS 
    HTGRPSLKKT VADSVRNKAN FINRHLFNHK RTGSNASHKS NASNAPSTSS NTNLTSHPVA 
    MGNLGTIESG GSGSAGSYTG TPRFYTPSAT PGGGSGMAIS DNPNYRLLDE SIASEQATIL 
    TTSSPNPNYE MMHPPTSLVS TNPNYMPMNE TPVQMAGVTI SHNPNYQPMQ APLNARQSQS 
    SSDEDNEQEE DDEDEDDDVD DEHVEHIKME RMPLSRPRQR ALPSKTQPPR SRSVSQTRKS 
    PTNPNSGIGA TGAGNRSNLL KENWLRPAST PRPPPPNGFI GREA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.