Details for: Fadd

Gene ID: 42594

Symbol: Fadd

Ensembl ID: FBgn0038928

Description: Fas-associated death domain

Associated with

Other Information

Genular Protein ID: 9280198

Symbol: FADD_DROME

Name: Fas-associated death domain protein

UniProtKB Accession Codes:

Q9V3B4 A4V9R5 A4V9R6 A4V9R7

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 DNASU 1 EMBL 10 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 1 GO 15 Gene3D 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MINT 1 NCBI Taxonomy 1 OMA 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 Reactome 4 RefSeq 1 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10934188

Title: dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD.

PubMed ID: 10934188

DOI: 10.1074/jbc.c000341200

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 17465907

Title: A screen for immunity genes evolving under positive selection in Drosophila.

PubMed ID: 17465907

DOI: 10.1111/j.1420-9101.2007.01305.x

PubMed ID: 12433364

Title: The Drosophila immune defense against Gram-negative infection requires the death protein dFADD.

PubMed ID: 12433364

DOI: 10.1016/s1074-7613(02)00454-5

PubMed ID: 22549468

Title: Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling.

PubMed ID: 22549468

DOI: 10.1038/emboj.2012.121

Sequence Information:

  • Length: 239
  • Mass: 27421
  • Checksum: F43CFAA546C3FCD9
  • Sequence:
    • MTAGRHWSYD SLKQIAIDGC TENVEQLKLI FVEEIGSRRR SDCIRTIEDL IDCLERADEL 
SEYNVEPLRR ISGNMPQLIE ALSAYTKPEN ILGHPVNLYQ ELRLAEELRQ QLRIAPASQN 
AQPSVSELAA AVPPTAIQNY ATPAAFTDHK RTMVFKKISE ELGRYWRRLG RSAGIGEGQM 
DTIEERYPHD LKSQILRLLQ LIEEDDCHDP KHFLLRLCRA LGDCGRNDLR KRVEQIMSH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.