Details for: hh

Gene ID: 42737

Symbol: hh

Description: hedgehog

Associated with

Other Information

Genular Protein ID: 2204917458

Symbol: HH_DROME

Name: Protein hedgehog N-product

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8166882

Title: Structure and expression of hedgehog, a Drosophila segment-polarity gene required for cell-cell communication.

PubMed ID: 8166882

DOI: 10.1016/0378-1119(93)90392-g

PubMed ID: 1394430

Title: Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog.

PubMed ID: 1394430

DOI: 10.1016/0092-8674(92)90264-d

PubMed ID: 1280560

Title: Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila.

PubMed ID: 1280560

DOI: 10.1242/dev.115.4.957

PubMed ID: 1340474

Title: The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation.

PubMed ID: 1340474

DOI: 10.1101/gad.6.12b.2635

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 7885476

Title: The product of hedgehog autoproteolytic cleavage active in local and long-range signalling.

PubMed ID: 7885476

DOI: 10.1038/374363a0

PubMed ID: 11319862

Title: An acylatable residue of Hedgehog is differentially required in Drosophila and mouse limb development.

PubMed ID: 11319862

DOI: 10.1006/dbio.2001.0218

PubMed ID: 11486055

Title: Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal.

PubMed ID: 11486055

DOI: 10.1126/science.1064437

PubMed ID: 12586063

Title: Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog.

PubMed ID: 12586063

DOI: 10.1016/s1534-5807(03)00031-5

PubMed ID: 15691765

Title: The Drosophila ortholog of the human wnt inhibitor factor shifted controls the diffusion of lipid-modified hedgehog.

PubMed ID: 15691765

DOI: 10.1016/j.devcel.2004.12.018

PubMed ID: 15875013

Title: Lipoprotein particles are required for Hedgehog and Wingless signalling.

PubMed ID: 15875013

DOI: 10.1038/nature03504

PubMed ID: 25639794

Title: Bacterial uracil modulates Drosophila DUOX-dependent gut immunity via Hedgehog-induced signaling endosomes.

PubMed ID: 25639794

DOI: 10.1016/j.chom.2014.12.012

PubMed ID: 27195754

Title: Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.

PubMed ID: 27195754

DOI: 10.1371/journal.pgen.1006054

PubMed ID: 9335337

Title: Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins.

PubMed ID: 9335337

DOI: 10.1016/s0092-8674(01)80011-8

Sequence Information:

  • Length: 471
  • Mass: 52150
  • Checksum: 8ECD796A92FE7043
  • Sequence:
  • MDNHSSVPWA SAASVTCLSL DAKCHSSSSS SSSKSAASSI SAIPQEETQT MRHIAHTQRC 
    LSRLTSLVAL LLIVLPMVFS PAHSCGPGRG LGRHRARNLY PLVLKQTIPN LSEYTNSASG 
    PLEGVIRRDS PKFKDLVPNY NRDILFRDEE GTGADRLMSK RCKEKLNVLA YSVMNEWPGI 
    RLLVTESWDE DYHHGQESLH YEGRAVTIAT SDRDQSKYGM LARLAVEAGF DWVSYVSRRH 
    IYCSVKSDSS ISSHVHGCFT PESTALLESG VRKPLGELSI GDRVLSMTAN GQAVYSEVIL 
    FMDRNLEQMQ NFVQLHTDGG AVLTVTPAHL VSVWQPESQK LTFVFADRIE EKNQVLVRDV 
    ETGELRPQRV VKVGSVRSKG VVAPLTREGT IVVNSVAASC YAVINSQSLA HWGLAPMRLL 
    STLEAWLPAK EQLHSSPKVV SSAQQQNGIH WYANALYKVK DYVLPQSWRH D

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.