Nup98 96 | FBgn0039120 | NCBI 42816

Details for: Nup98 96

Gene ID: 42816

Symbol: Nup98 96

Ensembl ID: FBgn0039120

Description: Nucleoporin 98-96kD

Associated with

Cell cycle
(R-DME-1640170)
Cell cycle, mitotic
(R-DME-69278)
Gene expression (transcription)
(R-DME-74160)
Gene silencing by rna
(R-DME-211000)
Metabolism of proteins
(R-DME-392499)
Metabolism of rna
(R-DME-8953854)
Mitotic anaphase
(R-DME-68882)
Mitotic metaphase and anaphase
(R-DME-2555396)
Mitotic prophase
(R-DME-68875)
M phase
(R-DME-68886)
Nuclear envelope (ne) reassembly
(R-DME-2995410)
Nuclear envelope breakdown
(R-DME-2980766)
Nuclear pore complex (npc) disassembly
(R-DME-3301854)
Post-translational protein modification
(R-DME-597592)
Postmitotic nuclear pore complex (npc) reformation
(R-DME-9615933)
Processing of capped intron-containing pre-mrna
(R-DME-72203)
Sumo e3 ligases sumoylate target proteins
(R-DME-3108232)
Sumoylation
(R-DME-2990846)
Sumoylation of chromatin organization proteins
(R-DME-4551638)
Sumoylation of dna damage response and repair proteins
(R-DME-3108214)
Sumoylation of dna replication proteins
(R-DME-4615885)
Sumoylation of sumoylation proteins
(R-DME-4085377)
Transcriptional regulation by small rnas
(R-DME-5578749)
Transport of mature mrna derived from an intron-containing transcript
(R-DME-159236)
Transport of mature mrna derived from an intronless transcript
(R-DME-159231)
Transport of mature mrnas derived from intronless transcripts
(R-DME-159234)
Transport of mature transcript to cytoplasm
(R-DME-72202)
Transport of the slbp dependant mature mrna
(R-DME-159230)
Transport of the slbp independent mature mrna
(R-DME-159227)
Cellular response to ecdysone
(GO:0071390)
Cellular response to heat
(GO:0034605)
Chromatin
(GO:0000785)
Chromatin dna binding
(GO:0031490)
Cytoplasm
(GO:0005737)
Germ-line stem cell population maintenance
(GO:0030718)
Heat shock-mediated polytene chromosome puffing
(GO:0035080)
Larval lymph gland hemopoiesis
(GO:0035167)
Male germ-line stem cell population maintenance
(GO:0036098)
Negative regulation by host of viral transcription
(GO:0043922)
Nuclear localization sequence binding
(GO:0008139)
Nuclear pore
(GO:0005643)
Nuclear pore central transport channel
(GO:0044613)
Nuclear pore cytoplasmic filaments
(GO:0044614)
Nucleocytoplasmic transport
(GO:0006913)
Nucleus
(GO:0005634)
Polytene chromosome
(GO:0005700)
Polytene chromosome band
(GO:0005704)
Polytene chromosome puff
(GO:0005703)
Positive regulation of actin filament polymerization
(GO:0030838)
Positive regulation of defense response to virus by host
(GO:0002230)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of transcription initiation by rna polymerase ii
(GO:0060261)
Post-transcriptional tethering of rna polymerase ii gene dna at nuclear periphery
(GO:0000973)
Promoter-enhancer loop anchoring activity
(GO:0140585)
Promoter-specific chromatin binding
(GO:1990841)
Protein binding
(GO:0005515)
Protein import into nucleus
(GO:0006606)
Regulation of nucleocytoplasmic transport
(GO:0046822)
Response to ecdysone
(GO:0035075)
Rna binding
(GO:0003723)
Rna export from nucleus
(GO:0006405)
Serine hydrolase activity
(GO:0017171)
Structural constituent of nuclear pore
(GO:0017056)
Telomere tethering at nuclear periphery
(GO:0034398)

Other Information

Proteins

NUP98_DROME

Genular Protein ID: 3746121260

Symbol: NUP98_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VCH5 B8A421 Q6NP55

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 20144760

Title: Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm.

PubMed ID: 20144760

DOI: 10.1016/j.cell.2010.01.011

PubMed ID: 20144761

Title: Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes.

PubMed ID: 20144761

DOI: 10.1016/j.cell.2009.12.054

PubMed ID: 20547758

Title: Specific nucleoporin requirement for Smad nuclear translocation.

PubMed ID: 20547758

DOI: 10.1128/mcb.00124-10

PubMed ID: 21874015

Title: Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons.

PubMed ID: 21874015

DOI: 10.1038/nn.2922

PubMed ID: 21949861

Title: Nucleoporin98-96 function is required for transit amplification divisions in the germ line of Drosophila melanogaster.

PubMed ID: 21949861

DOI: 10.1371/journal.pone.0025087

PubMed ID: 25310983

Title: Nucleoporin Nup98 associates with Trx/MLL and NSL histone-modifying complexes and regulates Hox gene expression.

PubMed ID: 25310983

DOI: 10.1016/j.celrep.2014.09.002

PubMed ID: 25201876

Title: Pvr expression regulators in equilibrium signal control and maintenance of Drosophila blood progenitors.

PubMed ID: 25201876

DOI: 10.7554/elife.03626

PubMed ID: 25197089

Title: Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila.

PubMed ID: 25197089

DOI: 10.1073/pnas.1410087111

PubMed ID: 25852164

Title: The transcription factor FoxK participates with Nup98 to regulate antiviral gene expression.

PubMed ID: 25852164

DOI: 10.1128/mbio.02509-14

PubMed ID: 28554770

Title: The actin binding cytoskeletal protein Moesin is involved in nuclear mRNA export.

PubMed ID: 28554770

DOI: 10.1016/j.bbamcr.2017.05.020

PubMed ID: 28366641

Title: Metazoan nuclear pores provide a scaffold for poised genes and mediate induced enhancer-promoter contacts.

PubMed ID: 28366641

DOI: 10.1016/j.molcel.2017.02.020

Sequence Information:

Length: 1960
Mass: 210139
Checksum: 00A94D1CCC25CBFC
Sequence:

MFGGAKPSFG ATPAATSFGG FSGTTTTTPF GQSAFGKPAA PAFGNTSTFA AQPAQQSLFG 
AAATPAQPAG GLFGANTSTG FGSTATAQPT AFGAFSQPQQ TSNIFGSTQT AASTSLFGQS 
TLPAFGAAKP TMTAFGQTAA AQPTGSLFGQ PAAATSTTGF GGFGTSAPTT TNVFGSGTAS 
AFAQPQATAV GASGVNTGTA VAKYQPTIGT DTLMKSGQAN SVNTKQHCIT AMKEFEGKSL 
EELRLEDYMC GRKGPQAGNA PGAFGFGAQV TQPAQPASGG LFGSTAQPST GLFGQTVTEN 
KSMFGTTAFG QQPATNNAFG AATQQNNFLQ KPFGATTTTP FAAPAADASN PFGAKPAFGQ 
GGSLFGQAPA TSAAPAFGQT NTGFGGFGTT AGATQQSTLF GATPAADPNK SAFGLGTAAS 
AATTGFGFGA PATSTAGGGL FGNKPATSFA APTFGATSTA STPFSNFGLN TSTAATGGGL 
FNSGLNKPAT SGFGGFGATS AAPLNFNAGN TGGSLFGNTA KPGGGLFGGG TTTLGGTGAA 
PTGGLFGGGT TSFGGVGGSL GGGGFGMGTN NSLTGGIMGA QPTLGIMTPS HQPIHQQILA 
RVTSPYGDSP IFKDLKLSSE ADATRATNPA AQQAVLDLTS NQYKISTSNN PAPMKVKALG 
STLNRKSLFD GLEEFDASVE GFNLKPSAKR LVIKPKVKSV EGGNPSSSIG SAPNTPQSRP 
KGATPNKERE SFSGAIPSEP LPPAGNSPGA TNGRESQDNG RRESWLHPNN LEKVRQHNIQ 
TGMDQGSPHN STLNELVPRK PLDTYRPSST VRLSVSTIPE NPFEDQSSTI ARRETFTSQQ 
ANESVLSNRS NEAEDSAANQ SRLAIEAAAA EAADDESHPT GIVLRRVGYY TIPSLDDLRS 
YLAEDGSCVV PNFTVGREGY GNVFFGKEMD VAGLNLDEIV HFRNKEIIIY PDDENKPPIG 
QGLNRDAQVT LDQVWPLDKT KHEAIKDPQR LLEMDWEGKL RRVCDKNDTR FIEYRPETGS 
WVFRVKHFSK YGLGDSDEED ELPTDPKKAK IATLEAQQRA NAEKMTLNSL RQAQKISEDA 
ARNLDPKALV AGVASGFRPM DDTAEFLLMD KTQFFQAGGN SDFSMFDPPR QRPTITSPTA 
VLAQEMVGNE AHKMQLMKSS FFVEDNAPED EPMETTGRLL RHRKFFNVEP LVWKDGASES 
SSQYDFEHPS PALPISSSVS EASLMCDAHY EETSSMATGS IVAAVKETKF EMPVTKAFKF 
VCKPKVAPIK LRATTVPLPR SIAYEMRDNW IADLGFYKGR SFKLSFGPQN SLVLPSTYNN 
MQNLKEFTGP SLPVSMVFAP RSATDLSPSV MQLVEFNMVK GNEGFRESII PHLEVQLNDC 
LSVNVEGSEC PCIHPDSGTK LVSKHFSESL KQRNAGLKED YSVSVWSLLF ALWGDHDELV 
DLEKNSHYMV MCRRNLLSEW LENTLLGKDL LSKKVSTHSY LEHMLDLLSC HRVNEACELA 
FSYDDANLAL VLSQLSSGAV FRLLMEEQLF AWQQSKSDKY IDLERLKMYM LAAGAPMMQS 
SHGAINLLEN KNWLTALALQ LWYFTAPTSS ITDALNAYND AFQAEECYAE PPKPSYRDAP 
TDTKKPVYDL RYHLLQLHSK RMHSLEETLN PITHTADAMD FRLSWLLLQT LRALGYRHCS 
PLTEARLSVD FASQLENEGL WQWGIFVLLH IKQQTQRERA VQQMLQRNVS VSAKVALYAE 
ERFIVEELGI PMSWVDYAKA VKAGASGKHH LQAKYLLKAK HFATAHDVIF QHIAPDAIIN 
GKMKYLHSLL IQFEDTEGSS IRVPNWANQG QIFLDFIDIS AKFKQIRSVT NIADINARWE 
NLKPQLSELC SRISLLPCPT SKHRLCQSEI SQSLSCLVHG MCIVCPEMES STVLKVALER 
LPLPQEFASK ELRIWLEELL DKIQNEPPFS ERQQPTMMEI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nup98 96

Associated with

Other Information

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm. PubMed ID: 20144760

Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes. PubMed ID: 20144761

Specific nucleoporin requirement for Smad nuclear translocation. PubMed ID: 20547758

Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons. PubMed ID: 21874015

Nucleoporin98-96 function is required for transit amplification divisions in the germ line of Drosophila melanogaster. PubMed ID: 21949861

Nucleoporin Nup98 associates with Trx/MLL and NSL histone-modifying complexes and regulates Hox gene expression. PubMed ID: 25310983

Pvr expression regulators in equilibrium signal control and maintenance of Drosophila blood progenitors. PubMed ID: 25201876

Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila. PubMed ID: 25197089

The transcription factor FoxK participates with Nup98 to regulate antiviral gene expression. PubMed ID: 25852164

The actin binding cytoskeletal protein Moesin is involved in nuclear mRNA export. PubMed ID: 28554770

Metazoan nuclear pores provide a scaffold for poised genes and mediate induced enhancer-promoter contacts. PubMed ID: 28366641