Details for: Mettl3

Gene ID: 42844

Symbol: Mettl3

Ensembl ID: FBgn0039139

Description: Methyltransferase like 3

Associated with

Other Information

Genular Protein ID: 227756323

Symbol: MTA70_DROME

Name: N6-adenosine-methyltransferase MT-A70-like protein

UniProtKB Accession Codes:

Q9VCE6

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ChEBI 10 ComplexPortal 1 DIP 1 DNASU 1 EC 1 EMBL 2 EnsemblMetazoa 1 FlyBase 1 GO 15 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 Reactome 1 RefSeq 1 Rhea 3 SMR 1 STRING 1 SUPFAM 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 21873203

Title: Drosophila Inducer of MEiosis 4 (IME4) is required for Notch signaling during oogenesis.

PubMed ID: 21873203

DOI: 10.1073/pnas.1111577108

PubMed ID: 27919077

Title: m(6)A modulates neuronal functions and sex determination in Drosophila.

PubMed ID: 27919077

DOI: 10.1038/nature20568

PubMed ID: 27919081

Title: m(6)A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination.

PubMed ID: 27919081

DOI: 10.1038/nature20577

PubMed ID: 29535189

Title: Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d.

PubMed ID: 29535189

DOI: 10.1101/gad.309146.117

PubMed ID: 28675155

Title: The m6A pathway facilitates sex determination in Drosophila.

PubMed ID: 28675155

DOI: 10.1038/ncomms15737

PubMed ID: 29555755

Title: Xio is a component of the Drosophila sex determination pathway and RNA N6-methyladenosine-methyladenosine methyltransferase complex.

PubMed ID: 29555755

DOI: 10.1073/pnas.1720945115

Sequence Information:

  • Length: 608
  • Mass: 68101
  • Checksum: 00A2E06082E7FD2F
  • Sequence:
    • MADAWDIKSL KTKRNTLREK LEKRKKERIE ILSDIQEDLT NPKKELVEAD LEVQKEVLQA 
LSSCSLALPI VSTQVVEKIA GSSLEMVNFI LGKLANQGAI VIRNVTIGTE AGCEIISVQP 
KELKEILEDT NDTCQQKEEE AKRKLEVDDV DQPQEKTIKL ESTVARKEST SLDAPDDIMM 
LLSMPSTREK QSKQVGEEIL ELLTKPTAKE RSVAEKFKSH GGAQVMEFCS HGTKVECLKA 
QQATAEMAAK KKQERRDEKE LRPDVDAGEN VTGKVPKTES AAEDGEIIAE VINNCEAESQ 
ESTDGSDTCS SETTDKCTKL HFKKIIQAHT DESLGDCSFL NTCFHMATCK YVHYEVDTLP 
HINTNKPTDV KTKLSLKRSV DSSCTLYPPQ WIQCDLRFLD MTVLGKFAVV MADPPWDIHM 
ELPYGTMSDD EMRALGVPAL QDDGLIFLWV TGRAMELGRD CLKLWGYERV DELIWVKTNQ 
LQRIIRTGRT GHWLNHGKEH CLVGMKGNPT NLNRGLDCDV IVAEVRATSH KPDEIYGIIE 
RLSPGTRKIE LFGRPHNIQP NWITLGNQLD GIRLVDPELI TQFQKRYPDG NCMSPASANA 
ASINGIQK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.