Tsc1 | FBgn0026317 | NCBI 42862

Details for: Tsc1

Gene ID: 42862

Symbol: Tsc1

Ensembl ID: FBgn0026317

Description: Tsc1

Associated with

Autophagy
(R-DME-9612973)
Energy dependent regulation of mtor by lkb1-ampk
(R-DME-380972)
Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Inhibition of tsc complex formation by pkb
(R-DME-165181)
Macroautophagy
(R-DME-1632852)
Membrane trafficking
(R-DME-199991)
Mtor signalling
(R-DME-165159)
Rab regulation of trafficking
(R-DME-9007101)
Rna polymerase ii transcription
(R-DME-73857)
Tbc/rabgaps
(R-DME-8854214)
Tp53 regulates metabolic genes
(R-DME-5628897)
Transcriptional regulation by tp53
(R-DME-3700989)
Vesicle-mediated transport
(R-DME-5653656)
Cellular response to chloroquine
(GO:1902350)
Cellular response to hypoxia
(GO:0071456)
Cholesterol homeostasis
(GO:0042632)
Cytoplasm
(GO:0005737)
Determination of adult lifespan
(GO:0008340)
Enteroendocrine cell differentiation
(GO:0035883)
Gtpase activator activity
(GO:0005096)
Intestinal stem cell homeostasis
(GO:0036335)
Kinase binding
(GO:0019900)
Larval midgut histolysis
(GO:0035069)
Lipid homeostasis
(GO:0055088)
Lymph gland development
(GO:0048542)
Negative regulation of cell growth
(GO:0030308)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of cell size
(GO:0045792)
Negative regulation of developmental growth
(GO:0048640)
Negative regulation of imaginal disc growth
(GO:0045571)
Negative regulation of insulin receptor signaling pathway
(GO:0046627)
Negative regulation of organ growth
(GO:0046621)
Negative regulation of torc1 signaling
(GO:1904262)
Negative regulation of tor signaling
(GO:0032007)
Negative regulation of vascular endothelial growth factor receptor signaling pathway
(GO:0030948)
Oogenesis
(GO:0048477)
Open tracheal system development
(GO:0007424)
Positive regulation of autophagy
(GO:0010508)
Positive regulation of hippo signaling
(GO:0035332)
Positive regulation of torc2 signaling
(GO:1904515)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Regulation of cell cycle
(GO:0051726)
Regulation of cell population proliferation
(GO:0042127)
Regulation of phosphorylation
(GO:0042325)
Regulation of terminal button organization
(GO:2000331)
Regulation of timing of cell differentiation
(GO:0048505)
Response to nutrient
(GO:0007584)
Signal transduction
(GO:0007165)
Tsc1-tsc2 complex
(GO:0033596)

Other Information

Proteins

Q9VCC9_DROME

Genular Protein ID: 2511457121

Symbol: Q9VCC9_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VCC9

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

Length: 1100
Mass: 124820
Checksum: F88EB6362BE7DC5B
Sequence:

MVIEKIIGDL ESNMTLENEE AKRKLVELLS QNKEQWVVKF MLDYFFTTGS QRILEVLVKA 
QAPHDGYIFD KLDDCLKQSQ HRVQSLQVFC FIVRHHPTWL YKIEKHRLIK SVFKLMTHEK 
EIVPLMSALL CIITLLPIIP NSVPNFLNDL FEVFGHLASW KLQNSNKLPD EKLVHLQLGL 
QMLFHRLYGM YPCSFIAYLV EFIKRGNGGG IFQHTIKPLL NTVRVHPMLV TATPETEVNN 
TRWKEMEPHD VVMECANLSL PVLLPETSNE DGSYAYPMTP GYSRMTSNTS NTDYSYQLRE 
FQQSRNVYTR FDSFASGDDV GPIWSPHNEI ATTSSGIPLT PTTSFILPLQ PAMNSQLMVG 
MTGSSPPEAA VEATPETTPL KDMRDIKQPG RAVNSHAVRA IFAVSQPSSP MRKDQQSQFS 
FPDVSREAEE SSHSYLEVNR GTAYDRRLSQ VIQDRHNVER SVNTPCPSSL PEINSDLSLV 
GGSVYPSVTQ EVAAVCGECN ETDRNLCSVG GLHMPTSRSM HQLAKKRRNR MASYSGNGSC 
ADSRSSAAKK ASWSTEAENP MRRTKSCSAL SGMRQQHLEE NDDEADCSSQ RQRGENGNTQ 
KTGSRLQRSG RNLAISAPKD TARSCTHAST QTVEGLDSAP AQYENWLIEL LLECKEQRID 
YERNLLYPQD ILDEYIKHAI KANESFDAEQ GQLMCLQLEY ESYRRSIHAE RNRRLMGRSR 
DKRSLEMERD RLREQLKNFD AKNKDLANKM DQAIRLANER QNIHQEELGE MRAKYQHELE 
EKKCLRQAND DLQTRLTSEL ARHKEMNYEL ESLRGQVFSL GTELQHTQQQ ADIGLQCKQE 
LARLEAEFII MGEVQVRCRD RLAEIDNFRA RDEELQMLQE SSNLELKDLR HSLDEKTSQL 
ESMKHKISDL QAQLANSEKA MTEQKRLLST VKDEYEEKFK SVNKKYDVQK KIIMQMEEKL 
MMMMQQPQGT TGHNTCSPDT DRTDIASSIE RNSPLSTSLA SSESLSASLR STELKNLHQL 
VDTPTIPDVL NSMAGGAQFE DEVRPPAVDL ASSASTASAI NIVPHALDLP STSGGIGHTL 
THPHPHPHLH LQQQQQDQLQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tsc1

Associated with

Other Information

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence. PubMed ID: 12537568

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective. PubMed ID: 12537573

Heterochromatic sequences in a Drosophila whole-genome shotgun assembly. PubMed ID: 12537574

Combined evidence annotation of transposable elements in genome sequences. PubMed ID: 16110336

The Release 5.1 annotation of Drosophila melanogaster heterochromatin. PubMed ID: 17569856

Sequence finishing and mapping of Drosophila melanogaster heterochromatin. PubMed ID: 17569867

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. PubMed ID: 26109357

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. PubMed ID: 26109356

The Release 6 reference sequence of the Drosophila melanogaster genome. PubMed ID: 25589440