p38a | FBgn0015765 | NCBI 42866

Details for: p38a

Gene ID: 42866

Symbol: p38a

Ensembl ID: FBgn0015765

Description: p38a MAP kinase

Associated with

Activated tak1 mediates p38 mapk activation
(R-DME-450302)
Activation of the ap-1 family of transcription factors
(R-DME-450341)
Adp signalling through p2y purinoceptor 1
(R-DME-418592)
Cellular responses to stimuli
(R-DME-8953897)
Cellular responses to stress
(R-DME-2262752)
Cellular senescence
(R-DME-2559583)
Cytokine signaling in immune system
(R-DME-1280215)
Developmental biology
(R-DME-1266738)
Erk/mapk targets
(R-DME-198753)
Hemostasis
(R-DME-109582)
Immune system
(R-DME-168256)
Innate immune system
(R-DME-168249)
Interleukin-17 signaling
(R-DME-448424)
Mapk1/mapk3 signaling
(R-DME-5684996)
Mapk family signaling cascades
(R-DME-5683057)
Map kinase activation
(R-DME-450294)
Mapk targets/ nuclear events mediated by map kinases
(R-DME-450282)
Mitf-m-dependent gene expression
(R-DME-9856651)
Mitf-m-regulated melanocyte development
(R-DME-9730414)
Myd88 cascade initiated on plasma membrane
(R-DME-975871)
Myd88 dependent cascade initiated on endosome
(R-DME-975155)
Myd88-independent tlr4 cascade
(R-DME-166166)
Myd88:mal(tirap) cascade initiated on plasma membrane
(R-DME-166058)
Myogenesis
(R-DME-525793)
Negative regulation of mapk pathway
(R-DME-5675221)
Neutrophil degranulation
(R-DME-6798695)
Nod1/2 signaling pathway
(R-DME-168638)
Nuclear events (kinase and transcription factor activation)
(R-DME-198725)
Nucleotide-binding domain, leucine rich repeat containing receptor (nlr) signaling pathways
(R-DME-168643)
Oxidative stress induced senescence
(R-DME-2559580)
P38mapk events
(R-DME-171007)
Platelet activation, signaling and aggregation
(R-DME-76002)
Platelet homeostasis
(R-DME-418346)
Platelet sensitization by ldl
(R-DME-432142)
Raf/map kinase cascade
(R-DME-5673001)
Regulation of mitf-m-dependent genes involved in pigmentation
(R-DME-9824585)
Signal amplification
(R-DME-392518)
Signaling by interleukins
(R-DME-449147)
Signaling by ntrk1 (trka)
(R-DME-187037)
Signaling by ntrks
(R-DME-166520)
Signaling by receptor tyrosine kinases
(R-DME-9006934)
Signaling by vegf
(R-DME-194138)
Signalling to erks
(R-DME-187687)
Signalling to ras
(R-DME-167044)
Signal transduction
(R-DME-162582)
Toll-like receptor cascades
(R-DME-168898)
Toll like receptor 2 (tlr2) cascade
(R-DME-181438)
Toll like receptor 3 (tlr3) cascade
(R-DME-168164)
Toll like receptor 4 (tlr4) cascade
(R-DME-166016)
Toll like receptor 5 (tlr5) cascade
(R-DME-168176)
Toll like receptor 7/8 (tlr7/8) cascade
(R-DME-168181)
Toll like receptor 9 (tlr9) cascade
(R-DME-168138)
Toll like receptor 10 (tlr10) cascade
(R-DME-168142)
Toll like receptor tlr1:tlr2 cascade
(R-DME-168179)
Toll like receptor tlr6:tlr2 cascade
(R-DME-168188)
Traf6 mediated induction of nfkb and map kinases upon tlr7/8 or 9 activation
(R-DME-975138)
Trif (ticam1)-mediated tlr4 signaling
(R-DME-937061)
Vegfa-vegfr2 pathway
(R-DME-4420097)
Atp binding
(GO:0005524)
Cellular response to arsenic-containing substance
(GO:0071243)
Cellular response to cadmium ion
(GO:0071276)
Cellular response to reactive oxygen species
(GO:0034614)
Cytoplasm
(GO:0005737)
Defense response to bacterium
(GO:0042742)
Defense response to fungus
(GO:0050832)
Determination of adult lifespan
(GO:0008340)
Heart morphogenesis
(GO:0003007)
Immune response
(GO:0006955)
Intracellular signal transduction
(GO:0035556)
Mapk cascade
(GO:0000165)
Map kinase activity
(GO:0004707)
Mucosal immune response
(GO:0002385)
Negative regulation of antimicrobial humoral response
(GO:0008348)
Nucleus
(GO:0005634)
P38mapk cascade
(GO:0038066)
Paracrine signaling
(GO:0038001)
Positive regulation of cell size
(GO:0045793)
Protein serine/threonine kinase activity
(GO:0004674)
Regulation of adult chitin-containing cuticle pigmentation
(GO:0048082)
Regulation of cellular response to oxidative stress
(GO:1900407)
Response to heat
(GO:0009408)
Response to hydrogen peroxide
(GO:0042542)
Response to osmotic stress
(GO:0006970)
Response to oxidative stress
(GO:0006979)
Response to starvation
(GO:0042594)

Other Information

Proteins

MK38A_DROME

Genular Protein ID: 152919810

Symbol: MK38A_DROME

Name: N/A

UniProtKB Accession Codes:

O62618 A4V3C0 O46216 Q9TXB4

Database IDs:

Citations:

PubMed ID: 9417090

Title: Molecular cloning and characterization of a Drosophila p38 mitogen-activated protein kinase.

PubMed ID: 9417090

DOI: 10.1074/jbc.273.1.369

PubMed ID: 9584193

Title: A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression.

PubMed ID: 9584193

DOI: 10.1128/mcb.18.6.3527

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 1378625

Title: Primary structure, expression, and signal-dependent tyrosine phosphorylation of a Drosophila homolog of extracellular signal-regulated kinase.

PubMed ID: 1378625

DOI: 10.1073/pnas.89.14.6295

Sequence Information:

Length: 366
Mass: 42256
Checksum: B3592B869F97990E
Sequence:

MSVSITKKFY KLDINRTEWE IPDIYQDLQP VGSGAYGQVS KAVVRGTNMH VAIKKLARPF 
QSAVHAKRTY RELRLLKHMD HENVIGLLDI FHPHPANGSL ENFQQVYLVT HLMDADLNNI 
IRMQHLSDDH VQFLVYQILR GLKYIHSAGV IHRDLKPSNI AVNEDCELRI LDFGLARPTE 
NEMTGYVATR WYRAPEIMLN WMHYDQTVDI WSVGCIMAEL ITRRTLFPGT DHIHQLNLIM 
EMLGTPPAEF LKKISSESAR SYIQSLPPMK GRSFKNVFKN ANPLAIDLLE KMLELDAEKR 
ITAEEALSHP YLEKYAEPSV EQTSPPYDHS FEDMDLPVDK WKELIYKEVT NFKPPPSYAQ 
VLKDVK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: p38a

Associated with

Other Information

Molecular cloning and characterization of a Drosophila p38 mitogen-activated protein kinase. PubMed ID: 9417090

A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression. PubMed ID: 9584193

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569