ASCL1 | ENSG00000139352 | NCBI 429

Details for: ASCL1

Gene ID: 429

Symbol: ASCL1

Ensembl ID: ENSG00000139352

Description: achaete-scute family bHLH transcription factor 1

Associated with

Ngf-stimulated transcription
(R-HSA-9031628)
Nuclear events (kinase and transcription factor activation)
(R-HSA-198725)
Signaling by ntrk1 (trka)
(R-HSA-187037)
Signaling by ntrks
(R-HSA-166520)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signal transduction
(R-HSA-162582)
Adrenal chromaffin cell differentiation
(GO:0061104)
Bhlh transcription factor binding
(GO:0043425)
Carotid body glomus cell differentiation
(GO:0061103)
Cell maturation
(GO:0048469)
Cellular response to magnetism
(GO:0071259)
Central nervous system neuron development
(GO:0021954)
Cerebral cortex development
(GO:0021987)
Cerebral cortex gabaergic interneuron differentiation
(GO:0021892)
Chromatin
(GO:0000785)
Chromatin binding
(GO:0003682)
Commitment of neuronal cell to specific neuron type in forebrain
(GO:0021902)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
E-box binding
(GO:0070888)
Heart development
(GO:0007507)
Identical protein binding
(GO:0042802)
Lung epithelial cell differentiation
(GO:0060487)
Lung neuroendocrine cell differentiation
(GO:0061100)
Motor neuron migration
(GO:0097475)
Musculoskeletal movement, spinal reflex action
(GO:0050883)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of neuron differentiation
(GO:0045665)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neuroblast fate determination
(GO:0007400)
Neuroblast proliferation
(GO:0007405)
Neurogenesis
(GO:0022008)
Neuronal cell body
(GO:0043025)
Neuron development
(GO:0048666)
Neuron differentiation
(GO:0030182)
Neuron fate commitment
(GO:0048663)
Neuron fate specification
(GO:0048665)
Noradrenergic neuron development
(GO:0003358)
Noradrenergic neuron fate commitment
(GO:0003359)
Notch signaling pathway
(GO:0007219)
Nucleic acid binding
(GO:0003676)
Nucleus
(GO:0005634)
Olfactory pit development
(GO:0060166)
Oligodendrocyte development
(GO:0014003)
Peripheral nervous system neuron development
(GO:0048935)
Positive regulation of cell cycle
(GO:0045787)
Positive regulation of neural precursor cell proliferation
(GO:2000179)
Positive regulation of neurogenesis
(GO:0050769)
Positive regulation of neuron apoptotic process
(GO:0043525)
Positive regulation of neuron differentiation
(GO:0045666)
Positive regulation of notch signaling pathway
(GO:0045747)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Regulation of epithelial cell differentiation
(GO:0030856)
Regulation of gene expression
(GO:0010468)
Regulation of mitotic cell cycle
(GO:0007346)
Regulation of neurogenesis
(GO:0050767)
Regulation of timing of subpallium neuron differentiation
(GO:0060165)
Response to epidermal growth factor
(GO:0070849)
Response to folic acid
(GO:0051593)
Response to retinoic acid
(GO:0032526)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Sensory organ development
(GO:0007423)
Sequence-specific double-stranded dna binding
(GO:1990837)
Spinal cord association neuron differentiation
(GO:0021527)
Spinal cord oligodendrocyte cell fate specification
(GO:0021530)
Stomach neuroendocrine cell differentiation
(GO:0061102)
Subpallium neuron fate commitment
(GO:0060163)
Sympathetic ganglion development
(GO:0061549)
Sympathetic nervous system development
(GO:0048485)
Ventral spinal cord interneuron fate commitment
(GO:0060579)
Vestibular nucleus development
(GO:0021750)

Other Information

Proteins

ASCL1_HUMAN

Genular Protein ID: 3459854380

Symbol: ASCL1_HUMAN

Name: N/A

UniProtKB Accession Codes:

P50553 A8K3C4 Q9BQ30

Database IDs:

Citations:

PubMed ID: 8390674

Title: Identification of a human achaete-scute homolog highly expressed in neuroendocrine tumors.

PubMed ID: 8390674

DOI: 10.1073/pnas.90.12.5648

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10903890

Title: HASH-1 and E2-2 are expressed in human neuroblastoma cells and form a functional complex.

PubMed ID: 10903890

DOI: 10.1006/bbrc.2000.3090

Sequence Information:

Length: 236
Mass: 25454
Checksum: A7D784329305B49A
Sequence:

MESSAKMESG GAGQQPQPQP QQPFLPPAAC FFATAAAAAA AAAAAAAQSA QQQQQQQQQQ 
QQAPQLRPAA DGQPSGGGHK SAPKQVKRQR SSSPELMRCK RRLNFSGFGY SLPQQQPAAV 
ARRNERERNR VKLVNLGFAT LREHVPNGAA NKKMSKVETL RSAVEYIRAL QQLLDEHDAV 
SAAFQAGVLS PTISPNYSND LNSMAGSPVS SYSSDEGSYD PLSPEEQELL DFTNWF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ASCL1

Associated with

Other Information

Identification of a human achaete-scute homolog highly expressed in neuroendocrine tumors. PubMed ID: 8390674

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

HASH-1 and E2-2 are expressed in human neuroblastoma cells and form a functional complex. PubMed ID: 10903890

Database document:

PubMed ID: 8390674

PubMed ID: 14702039

PubMed ID: 15489334

PubMed ID: 10903890