Details for: tok

Gene ID: 42944

Symbol: tok

Ensembl ID: FBgn0004885

Description: tolkin

Associated with

Other Information

Genular Protein ID: 3064206847

Symbol: TOK_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7813777

Title: Characterization of tolloid-related-1: a BMP-1-like product that is required during larval and pupal stages of Drosophila development.

PubMed ID: 7813777

DOI: 10.1006/dbio.1994.1338

PubMed ID: 8536976

Title: The tolkin gene is a tolloid/BMP-1 homologue that is essential for Drosophila development.

PubMed ID: 8536976

DOI: 10.1093/genetics/141.1.271

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 15872004

Title: Matching catalytic activity to developmental function: tolloid-related processes Sog in order to help specify the posterior crossvein in the Drosophila wing.

PubMed ID: 15872004

DOI: 10.1242/dev.01838

PubMed ID: 16971470

Title: At the next stop sign turn right: the metalloprotease Tolloid-related 1 controls defasciculation of motor axons in Drosophila.

PubMed ID: 16971470

DOI: 10.1242/dev.02580

PubMed ID: 17119021

Title: The metalloprotease tolloid-related and its TGF-beta-like substrate Dawdle regulate Drosophila motoneuron axon guidance.

PubMed ID: 17119021

DOI: 10.1242/dev.02711

PubMed ID: 16781701

Title: Graded maternal short gastrulation protein contributes to embryonic dorsal-ventral patterning by delayed induction.

PubMed ID: 16781701

DOI: 10.1016/j.ydbio.2006.04.453

PubMed ID: 32994163

Title: Proteolytic cleavage of Slit by the Tolkin protease converts an axon repulsion cue to an axon growth cue in vivo.

PubMed ID: 32994163

DOI: 10.1242/dev.196055

PubMed ID: 35709766

Title: BMP-gated cell-cycle progression drives anoikis during mesenchymal collective migration.

PubMed ID: 35709766

DOI: 10.1016/j.devcel.2022.05.017

Sequence Information:

  • Length: 1464
  • Mass: 165219
  • Checksum: 029BE1560DBE9056
  • Sequence:
  • MRRRRGTPLG VSWTNCVLLL ATGLLVVLIS VHAKNPRPHR GLPAPAPAPV PASVDQVATE 
    NAHRREPTVD GSVLQRLSGS DRAVDEDEDV DEDEDEGLKH QHLEHRQQFD AYLGTIRRLR 
    RPYRSKYTIE QLMRLHVTPK VSGDIDMDPC KAGGFMGDIA LPEGDSGPVV AHTPIDDEEQ 
    ERQEVEQLLA DSPSPVHDPP SVSGAANSGP TKFNATFQLD LEKLKQEVYH EGLQVEEEGL 
    TDIIRKKTKL PSSGPVNLKA GQSQSQSQSA NEPVKPGSES PSDYAQASSY KNEVLPPSEQ 
    RIHTDKPARL TLAEIGPKFS NKTQSLHRNV DTRKIQSDNK DIEDDSGNNF VAERRPSQIV 
    PTSLPEQRST PAHVYSNAGG NGMQLDDEVD FLHSRGVVRR RHRRGPKQRR SNQHLEHEVK 
    LQRLREELSR PVIEAHHHQS HHQKQAQHRQ HHQSHHRKKH RRQQQHHRRR GQSTTQYVNH 
    SPPGFNQSQQ AQQQSVPEMD LLKAETSKDE EPLRHRVARA VTAKKERIWD YGVIPYEIDG 
    NFSGIHKALF KLAMRHWENS TCIKFVERDP EIHPNYIVFT VRSCGCCSFV GKRGNGPQAI 
    SIGRNCDKFG IVVHELGHVV GFWHEHTRPD REKHVVIEHN NIMKGQDYNF NMLSPDEVDS 
    LGMAYDYDSI MHYARNTFSK GTYLDTILPI EMKGRKRPEI GQRLRLSQGD IAQANLLYKC 
    PKCGRTFQES SGIFASPSHY TAGALSNETE HCEWRITATY GERVELKLEN MNIFKSNNCE 
    TDYLEIRDGY FEKSPLIGRF CGKVDKEVIR TESSRMLLTY VNTHRIEGFR GFKAEFDVVC 
    GGELSVDDAV GRLESPNYPL DYLPNKECVW KITVPESYQV ALKFQSFEVE NHDSCVYDYV 
    EVRDGPGQDA PLIGVFCGYK PPPNMKSSGN SMYVKFVSDT SVQKAGFSAV FMKEVDECET 
    QNHGCEHECI NTLGGYECSC RIGFELHSDK KHCEDACGGV IEYPNGTITS PSFPEMYPLL 
    KECIWEIVAP PKHRISLNFT HFDLEGTAHQ QSDCGYDSVT VYSKLGENRL KRIGTFCGSS 
    IPPTATSESN ALRLEFHSDK SIQRSGFAAV FFTDIDECAV NNGGCQHECR NTIGSYICMC 
    HNGYSMHENG HDCKEGECKY EISAPFGTIF SPNYPDSYPP NADCVWHFIT TPGHRIKLIF 
    NEFDVESHQE CTYDNVAVYD GESESSSVLG RFCGDKIPFP ISSTSNQMYM VLKTDKNKQK 
    NGFTASHSTA CGGYLRATSQ VQQFYSHARF GNQDYDDGMD CEWTIAAPDN SYVQLIFLTF 
    DIESSENCTF DYVQVFSDID DVYGQYGPMY GQYCGNVLPQ DINSMTHSLL VRFKTDGSVP 
    MKGFSASYVA VPNSGEYDHS DEDVENSYSS EMVTPFPGSL KSIYIEDTQE ETDEYSDFSG 
    NQLVFNGQYR GRYSLPKRYY SGKA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.