Details for: Nct

Gene ID: 42964

Symbol: Nct

Ensembl ID: FBgn0039234

Description: Nicastrin

Associated with

Other Information

Genular Protein ID: 3213629936

Symbol: NICA_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10993067

Title: Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing.

PubMed ID: 10993067

DOI: 10.1038/35024009

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 11781576

Title: Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila.

PubMed ID: 11781576

DOI: 10.1038/ncb1201-1129

PubMed ID: 11782315

Title: Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor.

PubMed ID: 11782315

DOI: 10.1016/s1534-5807(01)00105-8

PubMed ID: 11782316

Title: Drosophila nicastrin is essential for the intramembranous cleavage of notch.

PubMed ID: 11782316

DOI: 10.1016/s1534-5807(01)00109-5

PubMed ID: 12660785

Title: The role of presenilin cofactors in the gamma-secretase complex.

PubMed ID: 12660785

DOI: 10.1038/nature01506

Sequence Information:

  • Length: 695
  • Mass: 77993
  • Checksum: C9D9D0C05CDC772B
  • Sequence:
  • MEMRLNAASI WLLILSYGAT IAQGERTRDK MYEPIGGASC FRRLNGTHQT GCSSTYSGSV 
    GVLHLINVEA DLEFLLSSPP SPPYAPMIPP HLFTRNNLMR LKEAGPKNIS VVLLINRTNQ 
    MKQFSHELNC PNQYSGLNST SETCDASNPA KNWNPWGTGL LHEDFPFPIY YIADLDQVTK 
    LEKCFQDFNN HNYETHALRS LCAVEVKSFM SAAVNTEVCM RRTNFINNLG GSKYCDPLEG 
    RNVYATLYPR KPAIENNLET VHTNEKFILV TCRLDTTTMF DGVGLGAMDS LMGFAVFTHV 
    AYLLKQLLPP QSKDLHNVLF VTFNGESYDY IGSQRFVYDM EKLQFPTEST GTPPIAFDNI 
    DFMLDIGTLD DISNIKLHAL NGTTLAQQIL ERLNNYAKSP RYGFNLNIQS EMSAHLPPTS 
    AQSFLRRDPN FNALILNARP TNKYYHSIYD DADNVDFTYA NTSKDFTQLT EVNDFKSLNP 
    DSLQMKVRNV SSIVAMALYQ TITGKEYTGT KVANPLMADE FLYCFLQSAD CPLFKAASYP 
    GSQLTNLPPM RYISVLGGSQ ESSGYTYRLL GYLLSQLQPD IHRDNCTDLP LHYFAGFNNI 
    GECRLTTQNY SHALSPAFLI DGYDWSSGMY STWTESTWSQ FSARIFLRPS NVHQVTTLSV 
    GIVVLIISFC LVYIISSRSE VLFEDLPASN AALFG

Genular Protein ID: 2293475151

Symbol: A0A0B4KHG2_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 699
  • Mass: 78389
  • Checksum: 1259C49E85B76250
  • Sequence:
  • MEMRLNAASI WLLILSYGAT IAQGERTRDK MYEPIGGASC FRRLNGTHQT GCSSTYSGSV 
    GVLHLINVEA DLEFLLSSPP SPPYAPMIPP HLFTRNNLMR LKEAGPKNIS VVLLINRTNQ 
    MKQFSHELNC PNQYSGLNST SETCDASNPA KNWNPWGTGL LHEDFPFPIY YIADLDQVTK 
    LEKCFQDFNN HNYETHALRS LCAVEVKSFM SAAVNTEVCM RRTNFINNLG GSKYCDPLEG 
    RNVYATLYPR KPAIENNLET VHTNEKFILV TCRLDTTTMF DGVGLGAMDS LMGFAVFTHV 
    AYLLKQLLPP QSKDLHNVLF VTFNGESYDY IGSQRFVYDM EKLQFPTEST GTPPIAFDNI 
    DFMLDIGTLD DISNIKLHAL NGTTLAQQIL ERLNNYAKSP RYGFNLNIQS EMSAHLPPTS 
    AQSFLRRDPN FNALILNARP TNKYYHSIYD DADNVDFTYA NTSKDFTQLT EVNDFKSLNP 
    DSLQMKVRNV SSIVAMALYQ TITGKEYTGT KVANPLMADE FLYCFLQSAD CPLFKAASYP 
    GSQLTNLPPM RYISVLGGSQ ESSGYTYRLL GYLLSQLQPD IHRDNCTDLP LHYFAGFNNI 
    GECRLTTQNY SHALSPAFLI DGYDWSSGMY STWTESTWSQ FSARIFLRPS NVHQVTTLSV 
    GIVVLIISFC LVYIISSRSE VLFEDLPASN AASPRPTAC

Genular Protein ID: 744707264

Symbol: Q7KS07_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 692
  • Mass: 77676
  • Checksum: A05CDC772BDA71DE
  • Sequence:
  • MEMRLNAASI WLLILSYGAT IAQGERTRDK MYEPIGGASC FRRLNGTHQT GCSSTYSGSV 
    GVLHLINVEA DLEFLLSSPP SPPYAPMIPP HLFTRNNLMR LKEAGPKNIS VVLLINRTNQ 
    MKQFSHELNC PNQYSGLNST SETCDASNPA KNWNPWGTGL LHEDFPFPIY YIADLDQVTK 
    LEKCFQDFNN HNYETHALRS LCAVEVKSFM SAAVNTEVCM RRTNFINNLG GSKYCDPLEG 
    RNVYATLYPR KPAIENNLET VHTNEKFILV TCRLDTTTMF DGVGLGAMDS LMGFAVFTHV 
    AYLLKQLLPP QSKDLHNVLF VTFNGESYDY IGSQRFVYDM EKLQFPTEST GTPPIAFDNI 
    DFMLDIGTLD DISNIKLHAL NGTTLAQQIL ERLNNYAKSP RYGFNLNIQS EMSAHLPPTS 
    AQSFLRRDPN FNALILNARP TNKYYHSIYD DADNVDFTYA NTSKDFTQLT EVNDFKSLNP 
    DSLQMKVRNV SSIVAMALYQ TITGKEYTGT KVANPLMADE FLYCFLQSAD CPLFKAASYP 
    GSQLTNLPPM RYISVLGGSQ ESSGYTYRLL GYLLSQLQPD IHRDNCTDLP LHYFAGFNNI 
    GECRLTTQNY SHALSPAFLI DGYDWSSGMY STWTESTWSQ FSARIFLRPS NVHQVTTLSV 
    GIVVLIISFC LVYIISSRSE VLFEDLPASN AA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.