Details for: Clbn

Gene ID: 43018

Symbol: Clbn

Ensembl ID: FBgn0259152

Description: Caliban

Associated with

  • Cat tailing
    (GO:0140708)
  • Cytoplasmic side of mitochondrial outer membrane
    (GO:0032473)
  • Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage
    (GO:1902231)
  • Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
    (GO:1902167)
  • Protein export from nucleus
    (GO:0006611)
  • Rescue of stalled ribosome
    (GO:0072344)
  • Ribosomal large subunit binding
    (GO:0043023)
  • Ribosome-associated ubiquitin-dependent protein catabolic process
    (GO:1990116)
  • Rqc complex
    (GO:1990112)
  • Trna binding
    (GO:0000049)

Other Information

Genular Protein ID: 2327034034

Symbol: NEMF_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VBX1 A8E6Q0

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 3 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 1 GO 11 Gene3D 1 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 3 PhylomeDB 1 Proteomes 1 RefSeq 2 SMR 1 STRING 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 16103875

Title: Drosophila caliban, a nuclear export mediator, can function as a tumor suppressor in human lung cancer cells.

PubMed ID: 16103875

DOI: 10.1038/sj.onc.1208962

PubMed ID: 22964637

Title: The tumor suppressor Caliban regulates DNA damage-induced apoptosis through p53-dependent and -independent activity.

PubMed ID: 22964637

DOI: 10.1038/onc.2012.395

PubMed ID: 30231800

Title: Drosophila Caliban mediates G1-S transition and ionizing radiation induced S phase checkpoint.

PubMed ID: 30231800

DOI: 10.1080/15384101.2018.1524237

PubMed ID: 31378462

Title: MISTERMINATE Mechanistically Links Mitochondrial Dysfunction with Proteostasis Failure.

PubMed ID: 31378462

DOI: 10.1016/j.molcel.2019.06.031

PubMed ID: 33057338

Title: Drosophila Caliban preserves intestinal homeostasis and lifespan through regulating mitochondrial dynamics and redox state in enterocytes.

PubMed ID: 33057338

DOI: 10.1371/journal.pgen.1009140

Sequence Information:

  • Length: 992
  • Mass: 112616
  • Checksum: 4F44719E1E54CBD4
  • Sequence:
    • MKTRFNTFDI ICGVAELQKL VGWRVNQIYD VDNKTYLFRM QGTGAVEKVT LLIESGTRFH 
TTRFEWPKNM APSGFSMKLR KHLKNKRLEK VQQMGSDRIV DFQFGTGDAA YHVILELYDR 
GNVILTDYEL TTLYILRPHT EGENLRFAMR EKYPVERAKQ PTKELELEAL VKLLENARNG 
DYLRQILTPN LDCGPAVIEH VLLSHGLDNH VIKKETTEET PEAEDKPEKG GKKQRKKQQN 
TKLEQKPFDM VNDLPILQQA VKDAQELIAE GNSGKSKGYI IQVKEEKPTE NGTVEFFFRN 
IEFHPYLFIQ FKNFEKATFE SFMEAVDEFY STQESQKIDM KTLQQEREAL KKLSNVKNDH 
AKRLEELTKV QDVDRKKAEL ITSNQSLVDN AIRAVQSAIA SQLSWPDIHE LVKEAQANGD 
AVASSIKQLK LETNHISLML SDPYDNDEDD DLKDPEVTVV DVDLALSAWA NARRYYDMKR 
SAAQKEKKTV DASQKALKSA ERKTQQTLKE VRTISNIVKA RKVFWFEKFY WFISSENYLV 
IGGRDAQQNE LIVKRYMRPK DIYVHAEIQG ASSVIIQNPT GEEIPPKTLL EAGSMAISYS 
VAWDAKVVTN SYWVTSDQVS KTAPTGEYLA TGSFMIRGKK NFLPSCHLTM GLSLLFKLED 
SFIERHLGER KVRSLEDDQI DPNVKENEVE HDLLSDNEDA DSNINLSEPS SNTEITAFPN 
TEVKIEHDTG RIIVRSDSVN PEIEETKESE VVLDKILKKT DDEETTIILA GPSRKKQVSA 
KKTKEDKARA KQEAAKQEVP PVSSEPKNPS QVKRGQKGKL KKMKQKYKDQ DDEEREIRMM 
ILKSSGKEKP QASADKVVEK SESTKEYVKP EKSAAPKNPV ELDDADEVPV GGDVDVLNSL 
TGQPHEGDEL LFAIPVVAPY QALQNYKFKV KLTPGTGKRG KAAKLALNIF AKEKSCSARE 
KDLLKSIKEE SLARNIPGKV KLSAPQLQKY HK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.