Details for: Tnks

Gene ID: 43095

Symbol: Tnks

Ensembl ID: FBgn0027508

Description: tankyrase

Associated with

  • Cytoplasm
    (GO:0005737)
  • Cytosol
    (GO:0005829)
  • Larval chitin-based cuticle development
    (GO:0008363)
  • Nad+-protein poly-adp-ribosyltransferase activity
    (GO:0003950)
  • Nucleus
    (GO:0005634)
  • Positive regulation of canonical wnt signaling pathway
    (GO:0090263)
  • Positive regulation of jnk cascade
    (GO:0046330)
  • Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
    (GO:0032436)
  • Positive regulation of protein catabolic process
    (GO:0045732)
  • Positive regulation of telomere capping
    (GO:1904355)
  • Positive regulation of ubiquitin-dependent protein catabolic process
    (GO:2000060)
  • Protein localization to chromosome, telomeric region
    (GO:0070198)
  • Segment polarity determination
    (GO:0007367)

Other Information

Genular Protein ID: 741837480

Symbol: TNKS_DROME

Name: Poly [ADP-ribose] polymerase tankyrase

UniProtKB Accession Codes:

Q9VBP3 Q9XZ37

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 12 ChiTaRS 1 DNASU 1 EC 1 EMBL 3 EMDB 1 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 1 GO 12 Gene3D 4 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 4 PaxDb 1 Pfam 4 PhylomeDB 1 Proteomes 1 RefSeq 1 Rhea 8 SMART 2 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10731138

Title: A Drosophila complementary DNA resource.

PubMed ID: 10731138

DOI: 10.1126/science.287.5461.2222

PubMed ID: 23622245

Title: Proteasome regulation by ADP-ribosylation.

PubMed ID: 23622245

DOI: 10.1016/j.cell.2013.03.040

Sequence Information:

  • Length: 1181
  • Mass: 127945
  • Checksum: EB6F0F94E6A3D504
  • Sequence:
    • MANSSRSRAI LSVNLDAVMA NDPLRELFEA CKTGEIAKVK KLITPQTVNA RDTAGRKSTP 
LHFAAGYGRR EVVEFLLNSG ASIQACDEGG LHPLHNCCSF GHAEVVRLLL KAGASPNTTD 
NWNYTPLHEA ASKGKVDVCL ALLQHGANHT IRNSEQKTPL ELADEATRPV LTGEYRKDEL 
LEAARSGAED RLLALLTPLN VNCHASDGRR STPLHLAAGY NRIGIVEILL ANGADVHAKD 
KGGLVPLHNA CSYGHFDVTK LLIQAGANVN ANDLWAFTPL HEAASKSRVE VCSLLLSRGA 
DPTLLNCHSK SAIDAAPTRE LRERIAFEYK GHCLLDACRK CDVSRAKKLV CAEIVNFVHP 
YTGDTPLHLA VVSPDGKRKQ LMELLTRKGS LLNEKNKAFL TPLHLAAELL HYDAMEVLLK 
QGAKVNALDS LGQTPLHRCA RDEQAVRLLL SYAADTNIVS LEGLTAAQLA SDSVLKLLKN 
PPDSETHLLE AAKAGDLDTV RRIVLNNPIS VNCRDLDGRH STPLHFAAGF NRVPVVQFLL 
EHGAEVYAAD KGGLVPLHNA CSYGHYEVTE LLVKHGANVN VSDLWKFTPL HEAAAKGKYD 
ICKLLLKHGA DPMKKNRDGA TPADLVKESD HDVAELLRGP SALLDAAKKG NLARVQRLVT 
PESINCRDAQ GRNSTPLHLA AGYNNFECAE YLLENGADVN AQDKGGLIPL HNASSYGHLD 
IAALLIKHKT VVNATDKWGF TPLHEAAQKG RTQLCSLLLA HGADAYMKNQ EGQTPIELAT 
ADDVKCLLQD AMATSLSQQA LSASTQSLTS SSPAPDATAA AAPGTSSSSS SAILSPTTET 
VLLPTGASMI LSVPVPLPLS SSTRISPAQG AEANGAEGSS SDDLLPDADT ITNVSGFLSS 
QQLHHLIELF EREQITLDIL AEMGHDDLKQ VGVSAYGFRH KILKGIAQLR STTGIGNNVN 
LCTLLVDLLP DDKEFVAVEE EMQATIREHR DNGQAGGYFT RYNIIRVQKV QNRKLWERYA 
HRRQEIAEEN FLQSNERMLF HGSPFINAIV QRGFDERHAY IGGMFGAGIY FAEHSSKSNQ 
YVYGIGGGIG CPSHKDKSCY VCPRQLLLCR VALGKSFLQY SAMKMAHAPP GHHSVVGRPS 
AGGLHFAEYV VYRGEQSYPE YLITYQIVKP DDSSSGTEDT R

Genular Protein ID: 336311127

Symbol: A0A0B4KI19_DROME

Name: N/A

UniProtKB Accession Codes:

A0A0B4KI19

Database IDs:

AGR 1 ARBA 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 1 Gene3D 4 GeneTree 1 InterPro 5 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 6 PROSITE-ProRule 1 Pfam 4 PhylomeDB 1 Proteomes 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 3 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 1520
  • Mass: 165680
  • Checksum: 115708F1F98A0C19
  • Sequence:
    • MANSSRSRAI LSVNLDAVMA NDPLRELFEA CKTGEIAKVK KLITPQTVNA RDTAGRKSTP 
LHFAAGYGRR EVVEFLLNSG ASIQACDEGG LHPLHNCCSF GHAEVVRLLL KAGASPNTTD 
NWNYTPLHEA ASKGKVDVCL ALLQHGANHT IRNSEQKTPL ELADEATRPV LTGEYRKDEL 
LEAARSGAED RLLALLTPLN VNCHASDGRR STPLHLAAGY NRIGIVEILL ANGADVHAKD 
KGGLVPLHNA CSYGHFDVTK LLIQAGANVN ANDLWAFTPL HEAASKSRVE VCSLLLSRGA 
DPTLLNCHSK SAIDAAPTRE LRERIAFEYK GHCLLDACRK CDVSRAKKLV CAEIVNFVHP 
YTGDTPLHLA VVSPDGKRKQ LMELLTRKGS LLNEKNKAFL TPLHLAAELL HYDAMEVLLK 
QGAKVNALDS LGQTPLHRCA RDEQAVRLLL SYAADTNIVS LEGLTAAQLA SDSVLKLLKN 
PPDSETHLLE AAKAGDLDTV RRIVLNNPIS VNCRDLDGRH STPLHFAAGF NRVPVVQFLL 
EHGAEVYAAD KGGLVPLHNA CSYGHYEVTE LLVKHGANVN VSDLWKFTPL HEAAAKGKYD 
ICKLLLKHGA DPMKKNRDGA TPADLVKESD HDVAELLRGP SALLDAAKKG NLARVQRLVT 
PESINCRDAQ GRNSTPLHLA AGYNNFECAE YLLENGADVN AQDKGGLIPL HNASSYGHLD 
IAALLIKHKT VVNATDKWGF TPLHEAAQKG RTQLCSLLLA HGADAYMKNQ EGQTPIELAT 
ADDVKCLLQD AMATSLSQQA LSASTQSLTS SSPAPDATAA AAPGTSSSSS SAILSPTTET 
VLLPTGASMI LSVPVPLPLS SSTRISPAQG AEANGAEGSS SDDLLPDADT ITNVSGFLSS 
QQLHHLIELF EREQITLDIL AEMGHDDLKQ VGVSAYGFRH KILKGIAQLR STTGIGNNVN 
LCTLLVDLLP DDKEFVAVEE EMQATIREHR DNGQAGGYFT RYNIIRVQKV QNRKLWERYA 
HRRQEIAEEN FLQSNERMLF HGSPFINAIV QRGFDERHAY IGGMFGAGIY FAEHSSKSNQ 
YVYGIGGGIG CPSHKDKSCY VCPRQLLLCR VALGKSFLQY SAMKMAHAPP GHHSVVGRPS 
AGGLHFAEYV VYRGEQSYPE YLITYQIVKP DDSSSGTEDT RXWMPSVGST PTTTSPALHQ 
PQTQQQPQQQ QQQQPQPQQQ QKAPLPLPPP QQQTSAPVAK RRPKHAKPSL QLQYQPYQPQ 
HHPVVATAAA VTTTQPSPAG VFAHSNNNNN TSSGNVNNNN NDMSPVSNSN SYSSVDTNQT 
LLNSLANQQR NHRQPQNHHH QQQQQANRSQ KYSQFMIITP AVSIDRDFEY ESHLDFEDFA 
NAAHNNGNLF RLGLRRSDSS SDDSGHSSDS SSFRSNYNPY LHHSRQHLLS KGGNGGGGGA 
SRHFYAFTSS WRWCSLLCAA MRCFGAGGAG HGNAPYSSSL QHHRLRRCSS YNAENAYEHF 
AAPFKARKTR DHMNNITYEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.