Details for: MME
Associated with
Other Information
Genular Protein ID: 3036555085
Symbol: NEP_HUMAN
Name: Atriopeptidase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2971756
Title: Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase.
PubMed ID: 2971756
PubMed ID: 2968607
Title: Molecular cloning of the common acute lymphoblastic leukemia antigen (CALLA) identifies a type II integral membrane protein.
PubMed ID: 2968607
PubMed ID: 2528730
Title: Organization of the gene encoding common acute lymphoblastic leukemia antigen (neutral endopeptidase 24.11): multiple miniexons and separate 5' untranslated regions.
PubMed ID: 2528730
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 3162217
Title: Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase).
PubMed ID: 3162217
PubMed ID: 6349683
Title: Human kidney 'enkephalinase', a neutral metalloendopeptidase that cleaves active peptides.
PubMed ID: 6349683
DOI: 10.1021/bi00282a035
PubMed ID: 6208535
Title: Hydrolysis of substance p and neurotensin by converting enzyme and neutral endopeptidase.
PubMed ID: 6208535
PubMed ID: 2972276
Title: Hydrolysis of alpha-human atrial natriuretic peptide in vitro by human kidney membranes and purified endopeptidase-24.11. Evidence for a novel cleavage site.
PubMed ID: 2972276
DOI: 10.1042/bj2540531
PubMed ID: 2531377
Title: Endopeptidase-24.11 in human plasma degrades atrial natriuretic factor (ANF) to ANF(99-105/106-126).
PubMed ID: 2531377
PubMed ID: 8168535
Title: Asp650 is crucial for catalytic activity of neutral endopeptidase 24-11.
PubMed ID: 8168535
PubMed ID: 12754519
Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.
PubMed ID: 12754519
DOI: 10.1038/nbt827
PubMed ID: 15283675
Title: Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism.
PubMed ID: 15283675
DOI: 10.1042/bj20040634
PubMed ID: 16254193
Title: Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro form.
PubMed ID: 16254193
PubMed ID: 17101991
Title: Human opiorphin, a natural antinociceptive modulator of opioid-dependent pathways.
PubMed ID: 17101991
PubMed ID: 20876573
Title: Neprilysin is identical to skin fibroblast elastase: its role in skin aging and UV responses.
PubMed ID: 20876573
PubMed ID: 19756956
Title: Neutral endopeptidase is a myristoylated protein.
PubMed ID: 19756956
PubMed ID: 22766194
Title: The human CD10 lacking an N-glycan at Asn(628) is deficient in surface expression and neutral endopeptidase activity.
PubMed ID: 22766194
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 27588448
Title: Rare variants in MME, encoding metalloprotease neprilysin, are linked to late-onset autosomal-dominant axonal polyneuropathies.
PubMed ID: 27588448
PubMed ID: 26991897
Title: Mutations in MME cause an autosomal-recessive Charcot-Marie-Tooth disease type 2.
PubMed ID: 26991897
DOI: 10.1002/ana.24612
PubMed ID: 27583304
Title: MME mutation in dominant spinocerebellar ataxia with neuropathy (SCA43).
PubMed ID: 27583304
PubMed ID: 26931059
Title: N-terminal domain of Bothrops asper Myotoxin II enhances the activity of endothelin converting enzyme-1 and neprilysin.
PubMed ID: 26931059
DOI: 10.1038/srep22413
PubMed ID: 27102936
Title: Corrigendum: N-terminal domain of Bothrops asper Myotoxin II enhances the activity of endothelin converting enzyme-1 and neprilysin.
PubMed ID: 27102936
DOI: 10.1038/srep24333
PubMed ID: 10669592
Title: Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon.
PubMed ID: 10669592
PubMed ID: 14747736
Title: Structural analysis of neprilysin with various specific and potent inhibitors.
PubMed ID: 14747736
PubMed ID: 17704566
Title: Structural studies of a bifunctional inhibitor of neprilysin and DPP-IV.
PubMed ID: 17704566
Sequence Information:
- Length: 750
- Mass: 85514
- Checksum: BCF3827C39898630
- Sequence:
MGKSESQMDI TDINTPKPKK KQRWTPLEIS LSVLVLLLTI IAVTMIALYA TYDDGICKSS DCIKSAARLI QNMDATTEPC TDFFKYACGG WLKRNVIPET SSRYGNFDIL RDELEVVLKD VLQEPKTEDI VAVQKAKALY RSCINESAID SRGGEPLLKL LPDIYGWPVA TENWEQKYGA SWTAEKAIAQ LNSKYGKKVL INLFVGTDDK NSVNHVIHID QPRLGLPSRD YYECTGIYKE ACTAYVDFMI SVARLIRQEE RLPIDENQLA LEMNKVMELE KEIANATAKP EDRNDPMLLY NKMTLAQIQN NFSLEINGKP FSWLNFTNEI MSTVNISITN EEDVVVYAPE YLTKLKPILT KYSARDLQNL MSWRFIMDLV SSLSRTYKES RNAFRKALYG TTSETATWRR CANYVNGNME NAVGRLYVEA AFAGESKHVV EDLIAQIREV FIQTLDDLTW MDAETKKRAE EKALAIKERI GYPDDIVSND NKLNNEYLEL NYKEDEYFEN IIQNLKFSQS KQLKKLREKV DKDEWISGAA VVNAFYSSGR NQIVFPAGIL QPPFFSAQQS NSLNYGGIGM VIGHEITHGF DDNGRNFNKD GDLVDWWTQQ SASNFKEQSQ CMVYQYGNFS WDLAGGQHLN GINTLGENIA DNGGLGQAYR AYQNYIKKNG EEKLLPGLDL NHKQLFFLNF AQVWCGTYRP EYAVNSIKTD VHSPGNFRII GTLQNSAEFS EAFHCRKNSY MNPEKKCRVW
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.