Details for: E spl mdelta HLH

Gene ID: 43150

Symbol: E spl mdelta HLH

Ensembl ID: FBgn0002734

Description: Enhancer of split mdelta, helix-loop-helix

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Protein dimerization activity
    (GO:0046983)
  • R1/r6 cell differentiation
    (GO:0048052)
  • R7 cell differentiation
    (GO:0045466)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of neuroblast proliferation
    (GO:1902692)
  • Regulation of neurogenesis
    (GO:0050767)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Somatic muscle development
    (GO:0007525)

Other Information

Genular Protein ID: 183719032

Symbol: ESMD_DROME

Name: Enhancer of split mdelta protein

UniProtKB Accession Codes:

Q01071 Q01897 Q4V723 Q56MT6 Q56MU1 Q56MU3 Q56MU4 Q56MU6 Q56MU8 Q56MV0 Q56MV5 Q56MV6 Q56MW2 Q56MW7 Q56MW9 Q56MX9 Q56MY0 Q56MY1 Q56N19 Q56N23 Q5S485 Q5S4A9 Q5S4K5

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 ELM 1 EMBL 100 EnsemblMetazoa 1 FlyBase 2 GO 15 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 RefSeq 1 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 UniProtKB 2 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 1427040

Title: Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins.

PubMed ID: 1427040

DOI: 10.1093/genetics/132.2.505

PubMed ID: 1528887

Title: The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins.

PubMed ID: 1528887

DOI: 10.1073/pnas.89.18.8731

PubMed ID: 15537803

Title: Identifying signatures of selection at the enhancer of split neurogenic gene complex in Drosophila.

PubMed ID: 15537803

DOI: 10.1093/molbev/msi046

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 16356268

Title: A low-cost open-source SNP genotyping platform for association mapping applications.

PubMed ID: 16356268

DOI: 10.1186/gb-2005-6-12-r105

PubMed ID: 8001118

Title: Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins.

PubMed ID: 8001118

DOI: 10.1016/0092-8674(94)90070-1

PubMed ID: 28899667

Title: bHLH-O proteins balance the self-renewal and differentiation of Drosophila neural stem cells by regulating Earmuff expression.

PubMed ID: 28899667

DOI: 10.1016/j.ydbio.2017.09.011

Sequence Information:

  • Length: 173
  • Mass: 20195
  • Checksum: F44DA6100CE0874F
  • Sequence:
    • MAVQGQRFMT KTQHYRKVTK PLLERKRRAR MNLYLDELKD LIVDTMDAQG EQVSKLEKAD 
ILELTVNYLK AQQQQRVANP QSPPPDQVNL DKFRAGYTQA AYEVSHIFST VPGLDLKFGT 
HLMKQLGHQL KDMKQEEEII DMAEEPVNLA DQKRSKSPRE EDIHHGEEVW RPW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.