Details for: E spl mbeta HLH

Gene ID: 43152

Symbol: E spl mbeta HLH

Ensembl ID: FBgn0002733

Description: Enhancer of split mbeta, helix-loop-helix

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Chaeta development
    (GO:0022416)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Positive regulation of neuroblast proliferation
    (GO:0002052)
  • Protein dimerization activity
    (GO:0046983)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of neuroblast proliferation
    (GO:1902692)
  • Regulation of neurogenesis
    (GO:0050767)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)

Other Information

Genular Protein ID: 330770758

Symbol: ESMB_DROME

Name: Enhancer of split mbeta protein

UniProtKB Accession Codes:

Q01069 Q01906 Q540X9 Q5S4K3 Q9VBJ0

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 ELM 1 EMBL 20 EnsemblMetazoa 1 FlyBase 1 GO 18 Gene3D 1 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 1528887

Title: The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins.

PubMed ID: 1528887

DOI: 10.1073/pnas.89.18.8731

PubMed ID: 1427040

Title: Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins.

PubMed ID: 1427040

DOI: 10.1093/genetics/132.2.505

PubMed ID: 15537803

Title: Identifying signatures of selection at the enhancer of split neurogenic gene complex in Drosophila.

PubMed ID: 15537803

DOI: 10.1093/molbev/msi046

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 22357926

Title: bHLH-O proteins are crucial for Drosophila neuroblast self-renewal and mediate Notch-induced overproliferation.

PubMed ID: 22357926

DOI: 10.1242/dev.071779

Sequence Information:

  • Length: 195
  • Mass: 21494
  • Checksum: 8ECAAC7E55D081DC
  • Sequence:
    • MVLEMEMSKT YQYRKVMKPM LERKRRARIN KCLDELKDIM VECLTQEGEH ITRLEKADIL 
ELTVEHMKKL RAQKQLRLSS VTGGVSPSAD PKLSIAESFR AGYVHAANEV SKTLAAVPGV 
SVDLGTQLMS HLGHRLNYLQ VVVPSLPIGV PLQAPVEDQA MVTPPPSECD SLESGACSPA 
PSEASSTSGP MWRPW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.