Details for: E spl m7 HLH

Gene ID: 43160

Symbol: E spl m7 HLH

Ensembl ID: FBgn0002633

Description: Enhancer of split m7, helix-loop-helix

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription factor binding
    (GO:0140297)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Protein dimerization activity
    (GO:0046983)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of neurogenesis
    (GO:0050767)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Transcription corepressor binding
    (GO:0001222)

Other Information

Genular Protein ID: 866786917

Symbol: ESM7_DROME

Name: Enhancer of split m7 protein

UniProtKB Accession Codes:

P13097 Q5S487 Q5S4J5 Q9VBI6

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 ELM 1 EMBL 19 EnsemblMetazoa 1 FlyBase 1 GO 15 Gene3D 1 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 2540957

Title: Closely related transcripts encoded by the neurogenic gene complex enhancer of split of Drosophila melanogaster.

PubMed ID: 2540957

DOI: 10.1002/j.1460-2075.1989.tb03365.x

PubMed ID: 15537803

Title: Identifying signatures of selection at the enhancer of split neurogenic gene complex in Drosophila.

PubMed ID: 15537803

DOI: 10.1093/molbev/msi046

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 8001118

Title: Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins.

PubMed ID: 8001118

DOI: 10.1016/0092-8674(94)90070-1

PubMed ID: 22357926

Title: bHLH-O proteins are crucial for Drosophila neuroblast self-renewal and mediate Notch-induced overproliferation.

PubMed ID: 22357926

DOI: 10.1242/dev.071779

Sequence Information:

  • Length: 186
  • Mass: 20687
  • Checksum: 9330530963CDCE15
  • Sequence:
    • MATKYEMSKT YQYRKVMKPL LERKRRARIN KCLDELKDLM AECVAQTGDA KFEKADILEV 
TVQHLRKLKE SKKHVPANPE QSFRAGYIRA ANEVSRALAS LPRVDVAFGT TLMTHLGMRL 
NQLEQPMEQP QAVNTPLSIV CGSSSSSSTY SSASSCSSIS PVSSGYASDN ESLLQISSPG 
QVWRPW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.