Details for: Tl

Gene ID: 43222

Symbol: Tl

Ensembl ID: FBgn0262473

Description: Toll

Associated with

Other Information

Genular Protein ID: 3489233203

Symbol: TOLL_DROME

Name: Protein toll

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2449285

Title: The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein.

PubMed ID: 2449285

DOI: 10.1016/0092-8674(88)90516-8

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12930753

Title: Natural selection drives Drosophila immune system evolution.

PubMed ID: 12930753

DOI: 10.1093/genetics/164.4.1471

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 3931919

Title: Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product.

PubMed ID: 3931919

DOI: 10.1016/0092-8674(85)90275-2

PubMed ID: 2124970

Title: The Drosophila membrane receptor Toll can function to promote cellular adhesion.

PubMed ID: 2124970

DOI: 10.1002/j.1460-2075.1990.tb07878.x

PubMed ID: 1879347

Title: Plasma membrane localization of the Toll protein in the syncytial Drosophila embryo: importance of transmembrane signaling for dorsal-ventral pattern formation.

PubMed ID: 1879347

DOI: 10.1242/dev.111.4.1021

PubMed ID: 8808632

Title: The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults.

PubMed ID: 8808632

DOI: 10.1016/s0092-8674(00)80172-5

PubMed ID: 10973475

Title: Toll-related receptors and the control of antimicrobial peptide expression in Drosophila.

PubMed ID: 10973475

DOI: 10.1073/pnas.180130797

PubMed ID: 12617819

Title: Tissue and stage-specific expression of the Tolls in Drosophila embryos.

PubMed ID: 12617819

DOI: 10.1016/s1567-133x(02)00020-0

PubMed ID: 12872120

Title: Binding of the Drosophila cytokine Spatzle to Toll is direct and establishes signaling.

PubMed ID: 12872120

DOI: 10.1038/ni955

PubMed ID: 15373972

Title: Toll and Toll-9 in Drosophila innate immune response.

PubMed ID: 15373972

DOI: 10.1179/096805104225004897

PubMed ID: 19018662

Title: Drosophila neurotrophins reveal a common mechanism for nervous system formation.

PubMed ID: 19018662

DOI: 10.1371/journal.pbio.0060284

PubMed ID: 22464169

Title: Virus recognition by Toll-7 activates antiviral autophagy in Drosophila.

PubMed ID: 22464169

DOI: 10.1016/j.immuni.2012.03.003

PubMed ID: 20504957

Title: Drosophila Tey represses transcription of the repulsive cue Toll and generates neuromuscular target specificity.

PubMed ID: 20504957

DOI: 10.1242/dev.046672

PubMed ID: 23596340

Title: Liesegang-like patterns of Toll crystals grown in gel.

PubMed ID: 23596340

DOI: 10.1107/s0021889812051606

PubMed ID: 24282309

Title: Cytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation.

PubMed ID: 24282309

DOI: 10.1073/pnas.1317002110

PubMed ID: 23245851

Title: Functional insights from the crystal structure of the N-terminal domain of the prototypical toll receptor.

PubMed ID: 23245851

DOI: 10.1016/j.str.2012.11.003

PubMed ID: 24733933

Title: Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.

PubMed ID: 24733933

DOI: 10.1073/pnas.1320678111

Sequence Information:

  • Length: 1097
  • Mass: 124656
  • Checksum: D1BFC42245E3EABE
  • Sequence:
  • MSRLKAASEL ALLVIILQLL QWPGSEASFG RDACSEMSID GLCQCAPIMS EYEIICPANA 
    ENPTFRLTIQ PKDYVQIMCN LTDTTDYQQL PKKLRIGEVD RVQMRRCMLP GHTPIASILD 
    YLGIVSPTTL IFESDNLGMN ITRQHLDRLH GLKRFRFTTR RLTHIPANLL TDMRNLSHLE 
    LRANIEEMPS HLFDDLENLE SIEFGSNKLR QMPRGIFGKM PKLKQLNLWS NQLHNLTKHD 
    FEGATSVLGI DIHDNGIEQL PHDVFAHLTN VTDINLSANL FRSLPQGLFD HNKHLNEVRL 
    MNNRVPLATL PSRLFANQPE LQILRLRAEL QSLPGDLFEH STQITNISLG DNLLKTLPAT 
    LLEHQVNLLS LDLSNNRLTH LPDSLFAHTT NLTDLRLEDN LLTGISGDIF SNLGNLVTLV 
    MSRNRLRTID SRAFVSTNGL RHLHLDHNDI DLQQPLLDIM LQTQINSPFG YMHGLLTLNL 
    RNNSIIFVYN DWKNTMLQLR ELDLSYNNIS SLGYEDLAFL SQNRLHVNMT HNKIRRIALP 
    EDVHLGEGYN NNLVHVDLND NPLVCDCTIL WFIQLVRGVH KPQYSRQFKL RTDRLVCSQP 
    NVLEGTPVRQ IEPQTLICPL DFSDDPRERK CPRGCNCHVR TYDKALVINC HSGNLTHVPR 
    LPNLHKNMQL MELHLENNTL LRLPSANTPG YESVTSLHLA GNNLTSIDVD QLPTNLTHLD 
    ISWNHLQMLN ATVLGFLNRT MKWRSVKLSG NPWMCDCTAK PLLLFTQDNF ERIGDRNEMM 
    CVNAEMPTRM VELSTNDICP AEKGVFIALA VVIALTGLLA GFTAALYYKF QTEIKIWLYA 
    HNLLLWFVTE EDLDKDKKFD AFISYSHKDQ SFIEDYLVPQ LEHGPQKFQL CVHERDWLVG 
    GHIPENIMRS VADSRRTIIV LSQNFIKSEW ARLEFRAAHR SALNEGRSRI IVIIYSDIGD 
    VEKLDEELKA YLKMNTYLKW GDPWFWDKLR FALPHRRPVG NIGNGALIKT ALKGSTDDKL 
    ELIKPSPVTP PLTTPPAEAT KNPLVAQLNG VTPHQAIMIA NGKNGLTNLY TPNGKSHGNG 
    HINGAFIINT NAKQSDV

Genular Protein ID: 353123870

Symbol: A0A0B4KHY4_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 1117
  • Mass: 127163
  • Checksum: F2378D963C549E14
  • Sequence:
  • MSRLKAASEL ALLVIILQLL QWPGSEASFG RDACSEMSID GLCQCAPIMS EYEIICPANA 
    ENPTFRLTIQ PKDYVQIMCN LTDTTDYQQL PKKLRIGEVD RVQMRRCMLP GHTPIASILD 
    YLGIVSPTTL IFESDNLGMN ITRQHLDRLH GLKRFRFTTR RLTHIPANLL TDMRNLSHLE 
    LRANIEEMPS HLFDDLENLE SIEFGSNKLR QMPRGIFGKM PKLKQLNLWS NQLHNLTKHD 
    FEGATSVLGI DIHDNGIEQL PHDVFAHLTN VTDINLSANL FRSLPQGLFD HNKHLNEVRL 
    MNNRVPLATL PSRLFANQPE LQILRLRAEL QSLPGDLFEH STQITNISLG DNLLKTLPAT 
    LLEHQVNLLS LDLSNNRLTH LPDSLFAHTT NLTDLRLEDN LLTGISGDIF SNLGNLVTLV 
    MSRNRLRTID SRAFVSTNGL RHLHLDHNDI DLQQPLLDIM LQTQINSPFG YMHGLLTLNL 
    RNNSIIFVYN DWKNTMLQLR ELDLSYNNIS SLGYEDLAFL SQNRLHVNMT HNKIRRIALP 
    EDVHLGEGYN NNLVHVDLND NPLVCDCTIL WFIQLVRGVH KPQYSRQFKL RTDRLVCSQP 
    NVLEGTPVRQ IEPQTLICPL DFSDDPRERK CPRGCNCHVR TYDKALVINC HSGNLTHVPR 
    LPNLHKNMQL MELHLENNTL LRLPSANTPG YESVTSLHLA GNNLTSIDVD QLPTNLTHLD 
    ISWNHLQMLN ATVLGFLNRT MKWRSVKLSG NPWMCDCTAK PLLLFTQDNF ERIGDRNEMM 
    CVNAEMPTRM VELSTNDICP AEKGVFIALA VVIALTGLLA GFTAALYYKF QTEIKIWLYA 
    HNLLLWFVTE EDLDKDKKFD AFISYSHKDQ SFIEDYLVPQ LEHGPQKFQL CVHERDWLVG 
    GHIPENIMRS VADSRRTIIV LSQNFIKSEW ARLEFRAAHR SALNEGRSRI IVIIYSDIGD 
    VEKLDEELKA YLKMNTYLKW GDPWFWDKLR FALPHRRPVG NIGNGALIKT ALKGSTDDKL 
    ELIKPSPVTP PLTTPPAEAT KNPLVAQLNG VTPHQAIMIA NGKNGLTNLY TPNGKSHGNG 
    HINGAFIINT NAKQSDVXDW EKAELFQFDP DDELLFR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.