Details for: ro

Gene ID: 43234

Symbol: ro

Ensembl ID: FBgn0003267

Description: rough

Associated with

  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Establishment of ommatidial planar polarity
    (GO:0042067)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • R2/r5 cell differentiation
    (GO:0048054)
  • R2/r5 cell fate commitment
    (GO:0007463)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific dna binding
    (GO:0043565)

Other Information

Genular Protein ID: 2436606632

Symbol: ROUGH_DROME

Name: Homeobox protein rough

UniProtKB Accession Codes:

P10181 Q24487 Q4V714 Q9VBA7

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 EMBL 5 EnsemblMetazoa 2 FlyBase 1 GO 10 Gene3D 1 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 2 PRINTS 1 PRO 1 PROSITE 2 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 2 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 2903798

Title: Rough, a Drosophila homeobox gene required in photoreceptors R2 and R5 for inductive interactions in the developing eye.

PubMed ID: 2903798

DOI: 10.1016/0092-8674(88)90133-x

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 2898735

Title: Pattern formation in the developing eye of Drosophila melanogaster is regulated by the homoeo-box gene, rough.

PubMed ID: 2898735

DOI: 10.1038/334151a0

PubMed ID: 1974228

Title: The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype.

PubMed ID: 1974228

DOI: 10.1101/gad.4.5.712

PubMed ID: 11709152

Title: senseless repression of rough is required for R8 photoreceptor differentiation in the developing Drosophila eye.

PubMed ID: 11709152

DOI: 10.1016/s0896-6273(01)00480-9

Sequence Information:

  • Length: 350
  • Mass: 39430
  • Checksum: D5A39EF19D39DEAF
  • Sequence:
    • MQRHKVEIGS PDGSPGIKRS DSLDPIANTT ILSVPQRPSS PRQFFERLYG HLETRSSENG 
EIDVGTHAHK PPPCDTPYHS DGGSVSSPDI SISDERTSLA AYPAYDFYGH AKDYPQHPSQ 
QHQQHHHHHH HPPQLVHQKL SYVSPPPAIA AGGAANPVLP HAFPAGFPSD PHFSAGFSAF 
LARRRRKEGR QRRQRTTFST EQTLRLEVEF HRNEYISRSR RFELAETLRL TETQIKIWFQ 
NRRAKDKRIE KAQIDQHYRN FVVANGFMSS IMGQAATTMP PGGVTGGVAV GVGLNYYAAA 
ATPAALPKDN TQDANFIDID DQFQRQQQQK QQQQQQQQRR RETTTPINIC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.