Sce | FBgn0003330 | NCBI 43327

Details for: Sce

Gene ID: 43327

Symbol: Sce

Ensembl ID: FBgn0003330

Description: Sex combs extra

Associated with

Cellular responses to stimuli
(R-DME-8953897)
Cellular responses to stress
(R-DME-2262752)
Cellular senescence
(R-DME-2559583)
Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Intracellular signaling by second messengers
(R-DME-9006925)
Metabolism of proteins
(R-DME-392499)
Oxidative stress induced senescence
(R-DME-2559580)
Pip3 activates akt signaling
(R-DME-1257604)
Post-translational protein modification
(R-DME-597592)
Pten regulation
(R-DME-6807070)
Regulation of pten gene transcription
(R-DME-8943724)
Rna polymerase ii transcription
(R-DME-73857)
Runx1 interacts with co-factors whose precise effect on runx1 targets is not known
(R-DME-8939243)
Signal transduction
(R-DME-162582)
Sumo e3 ligases sumoylate target proteins
(R-DME-3108232)
Sumoylation
(R-DME-2990846)
Sumoylation of dna damage response and repair proteins
(R-DME-3108214)
Sumoylation of rna binding proteins
(R-DME-4570464)
Sumoylation of transcription cofactors
(R-DME-3899300)
Transcriptional regulation by e2f6
(R-DME-8953750)
Transcriptional regulation by runx1
(R-DME-8878171)
Anterior/posterior axis specification
(GO:0009948)
Chromatin
(GO:0000785)
Chromatin binding
(GO:0003682)
Condensed chromosome, centromeric region
(GO:0000779)
Follicle cell of egg chamber stalk formation
(GO:0030713)
Germarium-derived female germ-line cyst encapsulation
(GO:0030708)
Heterochromatin formation
(GO:0031507)
Neurogenesis
(GO:0022008)
Nuclear envelope
(GO:0005635)
Nucleolus
(GO:0005730)
Nucleus
(GO:0005634)
Pcg protein complex
(GO:0031519)
Prc1 complex
(GO:0035102)
Protein binding
(GO:0005515)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin ligase complex
(GO:0000151)
Ubiquitin protein ligase activity
(GO:0061630)
Ventral cord development
(GO:0007419)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

E3 ubiquitin-protein ligase RING1

Genular Protein ID: 3764109125

Symbol: RING1_DROME

Name: E3 ubiquitin-protein ligase RING1

UniProtKB Accession Codes:

Q9VB08 O18380

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 11583617

Title: Reconstitution of a functional core polycomb repressive complex.

PubMed ID: 11583617

DOI: 10.1016/s1097-2765(01)00316-1

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 11493925

Title: A Drosophila Polycomb group complex includes Zeste and dTAFII proteins.

PubMed ID: 11493925

DOI: 10.1038/35088096

PubMed ID: 12963114

Title: Molecular and genetic analysis of the Polycomb group gene Sex combs extra/Ring in Drosophila.

PubMed ID: 12963114

DOI: 10.1016/s0925-4773(03)00083-2

PubMed ID: 15147763

Title: The Drosophila Polycomb group gene Sex combs extra encodes the ortholog of mammalian Ring1 proteins.

PubMed ID: 15147763

DOI: 10.1016/j.mod.2004.03.019

PubMed ID: 15567868

Title: Chromatin compaction by a polycomb group protein complex.

PubMed ID: 15567868

DOI: 10.1126/science.1100576

PubMed ID: 14967148

Title: Propagation of silencing; recruitment and repression of naive chromatin in trans by polycomb repressed chromatin.

PubMed ID: 14967148

DOI: 10.1016/s1097-2765(04)00006-1

PubMed ID: 15386022

Title: Role of histone H2A ubiquitination in Polycomb silencing.

PubMed ID: 15386022

DOI: 10.1038/nature02985

PubMed ID: 14669021

Title: A proposed role for the Polycomb group protein dRING in meiotic sister-chromatid cohesion.

PubMed ID: 14669021

DOI: 10.1007/s00412-003-0266-0

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

Length: 435
Mass: 47256
Checksum: 5DC5834BD3CC516C
Sequence:

MTSLDPAPNK TWELSLYELQ RKPQEVITDS TEIAVSPRSL HSELMCPICL DMLKKTMTTK 
ECLHRFCSDC IVTALRSGNK ECPTCRKKLV SKRSLRADPN FDLLISKIYP SREEYEAIQE 
KVMAKFNQTQ SQQALVNSIN EGIKLQSQNR PQRFRTKGGG GGGGGGGNGN GAANVAAPPA 
PGAPTAVGRN ASNQMHVHDT ASNDSNSNTN SIDRENRDPG HSGTSAASAI TSASNAAPSS 
SANSGASTSA TRMQVDDASN PPSVRSTPSP VPSNSSSSKP KRAMSVLTSE RSEESESDSQ 
MDCRTEGDSN IDTEGEGNGE LGINDEIELV FKPHPTEMSA DNQLIRALKE NCVRYIKTTA 
NATVDHLSKY LAMRLTLDLG ADLPEACRVL NFCIYVAPQP QQLVILNGNQ TLHQVNDKFW 
KVNKPMEMYY SWKKT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sce

Associated with

Other Information

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Reconstitution of a functional core polycomb repressive complex. PubMed ID: 11583617

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

A Drosophila Polycomb group complex includes Zeste and dTAFII proteins. PubMed ID: 11493925

Molecular and genetic analysis of the Polycomb group gene Sex combs extra/Ring in Drosophila. PubMed ID: 12963114

The Drosophila Polycomb group gene Sex combs extra encodes the ortholog of mammalian Ring1 proteins. PubMed ID: 15147763

Chromatin compaction by a polycomb group protein complex. PubMed ID: 15567868

Propagation of silencing; recruitment and repression of naive chromatin in trans by polycomb repressed chromatin. PubMed ID: 14967148

Role of histone H2A ubiquitination in Polycomb silencing. PubMed ID: 15386022

A proposed role for the Polycomb group protein dRING in meiotic sister-chromatid cohesion. PubMed ID: 14669021

Phosphoproteome analysis of Drosophila melanogaster embryos. PubMed ID: 18327897