ASIP | ENSG00000101440 | NCBI 434

Details for: ASIP

Gene ID: 434

Symbol: ASIP

Ensembl ID: ENSG00000101440

Description: agouti signaling protein

Associated with

Adult feeding behavior
(GO:0008343)
Cell-cell signaling
(GO:0007267)
Epigenetic programming in the zygotic pronuclei
(GO:0044725)
Extracellular space
(GO:0005615)
Generation of precursor metabolites and energy
(GO:0006091)
Hormone-mediated signaling pathway
(GO:0009755)
Melanin biosynthetic process
(GO:0042438)
Melanocortin receptor binding
(GO:0031779)
Melanosome organization
(GO:0032438)
Melanosome transport
(GO:0032402)
Neuropeptide hormone activity
(GO:0005184)
Positive regulation of melanin biosynthetic process
(GO:0048023)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Type 3 melanocortin receptor binding
(GO:0031781)
Type 4 melanocortin receptor binding
(GO:0031782)

Other Information

Proteins

Agouti-signaling protein

Genular Protein ID: 2857362054

Symbol: ASIP_HUMAN

Name: Agouti-signaling protein

UniProtKB Accession Codes:

P42127 Q3SXL2

Database IDs:

Citations:

PubMed ID: 7937887

Title: Molecular structure and chromosomal mapping of the human homolog of the agouti gene.

PubMed ID: 7937887

DOI: 10.1073/pnas.91.21.9760

PubMed ID: 7757071

Title: Structure and function of ASP, the human homolog of the mouse agouti gene.

PubMed ID: 7757071

DOI: 10.1093/hmg/4.2.223

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15701517

Title: Structures of the agouti signaling protein.

PubMed ID: 15701517

DOI: 10.1016/j.jmb.2004.12.030

PubMed ID: 11833005

Title: A polymorphism in the agouti signaling protein gene is associated with human pigmentation.

PubMed ID: 11833005

DOI: 10.1086/339076

PubMed ID: 36536132

Title: Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity.

PubMed ID: 36536132

DOI: 10.1038/s42255-022-00703-9

Sequence Information:

Length: 132
Mass: 14515
Checksum: AF82CC3C747F2BE6
Sequence:

MDVTRLLLAT LLVFLCFFTA NSHLPPEEKL RDDRSLRSNS SVNLLDVPSV SIVALNKKSK 
QIGRKAAEKK RSSKKEASMK KVVRPRTPLS APCVATRNSC KPPAPACCDP CASCQCRFFR 
SACSCRVLSL NC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ASIP

Associated with

Other Information

Molecular structure and chromosomal mapping of the human homolog of the agouti gene. PubMed ID: 7937887

Structure and function of ASP, the human homolog of the mouse agouti gene. PubMed ID: 7757071

The DNA sequence and comparative analysis of human chromosome 20. PubMed ID: 11780052

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Structures of the agouti signaling protein. PubMed ID: 15701517

A polymorphism in the agouti signaling protein gene is associated with human pigmentation. PubMed ID: 11833005

Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity. PubMed ID: 36536132