Details for: Cpsf100

Gene ID: 43426

Symbol: Cpsf100

Ensembl ID: FBgn0027873

Description: Cleavage and polyadenylation specificity factor 100

Associated with

  • Gene expression (transcription)
    (R-DME-74160)
  • Metabolism of rna
    (R-DME-8953854)
  • Mrna 3'-end processing
    (R-DME-72187)
  • Processing of capped intron-containing pre-mrna
    (R-DME-72203)
  • Processing of capped intronless pre-mrna
    (R-DME-75067)
  • Processing of intronless pre-mrnas
    (R-DME-77595)
  • Rna polymerase ii transcription
    (R-DME-73857)
  • Rna polymerase ii transcription termination
    (R-DME-73856)
  • Transport of mature mrna derived from an intronless transcript
    (R-DME-159231)
  • Transport of mature mrnas derived from intronless transcripts
    (R-DME-159234)
  • Transport of mature transcript to cytoplasm
    (R-DME-72202)
  • Co-transcriptional mrna 3'-end processing, cleavage and polyadenylation pathway
    (GO:0180010)
  • Mrna 3'-end processing by stem-loop binding and cleavage
    (GO:0006398)
  • Mrna cleavage and polyadenylation specificity factor complex
    (GO:0005847)
  • Protein binding
    (GO:0005515)
  • Rna binding
    (GO:0003723)

Other Information

Genular Protein ID: 1869232805

Symbol: CPSF2_DROME

Name: Probable cleavage and polyadenylation specificity factor subunit 2

UniProtKB Accession Codes:

Q9V3D6 Q8IML7

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 ComplexPortal 1 DNASU 1 EMBL 2 EnsemblMetazoa 1 FlyBase 1 GO 4 Gene3D 1 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 4 PhylomeDB 1 Proteomes 1 Reactome 5 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10731138

Title: A Drosophila complementary DNA resource.

PubMed ID: 10731138

DOI: 10.1126/science.287.5461.2222

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 19450530

Title: A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs.

PubMed ID: 19450530

DOI: 10.1016/j.molcel.2009.04.024

Sequence Information:

  • Length: 756
  • Mass: 85418
  • Checksum: E391D61CFA1DD821
  • Sequence:
    • MTSIIKLHTI SGAMDESPPC YILQIDDVRI LLDCGWDEKF DANFIKELKR QVHTLDAVLL 
SHPDAYHLGA LPYLVGKLGL NCPIYATIPV FKMGQMFMYD LYMSHFNMGD FDLFSLDDVD 
TAFEKITQLK YNQTVSLKDK GYGISITPLN AGHMIGGTIW KIVKVGEEDI VYATDFNHKK 
ERHLSGCELD RLQRPSLLIT DAYNAQYQQA RRRARDEKLM TNILQTVRNN GNVLIAVDTA 
GRVLELAHML DQLWKNKESG LMAYSLALLN NVSYNVIEFA KSQIEWMSDK LTKAFEGARN 
NPFQFKHIQL CHSLADVYKL PAGPKVVLAS TPDLESGFTR DLFVQWASNA NNSIILTTRT 
SPGTLAMELV ENCAPGKQIE LDVRRRVDLE GAELEEYLRT QGEKLNPLIV KPDVEEESSS 
ESEDDIEMSV ITGKHDIVVR PEGRHHSGFF KSNKRHHVMF PYHEEKVKCD EYGEIINLDD 
YRIADATGYE FVPMEEQNKE NVKKEEPGIG AEQQANGGIV DNDVQLLEKP TKLISQRKTI 
EVNAQVQRID FEGRSDGESM LKILSQLRPR RVIVIHGTAE GTQVVARHCE QNVGARVFTP 
QKGEIIDVTS EIHIYQVRLT EGLVSQLQFQ KGKDAEVAWV DGRLGMRVKA IEAPMDVTVE 
QDASVQEGKT LTLETLADDE IPIHNSVLIN ELKLSDFKQT LMRNNINSEF SGGVLWCSNG 
TLALRRVDAG KVAMEGCLSE EYYKIRELLY EQYAIV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.