Details for: Bub3

Gene ID: 43490

Symbol: Bub3

Ensembl ID: FBgn0025457

Description: Bub3

Associated with

  • Activation of apc/c and apc/c:cdc20 mediated degradation of mitotic proteins
    (R-DME-176814)
  • Apc-cdc20 mediated degradation of nek2a
    (R-DME-179409)
  • Apc/c-mediated degradation of cell cycle proteins
    (R-DME-174143)
  • Apc/c:cdc20 mediated degradation of mitotic proteins
    (R-DME-176409)
  • Apc:cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
    (R-DME-179419)
  • Cdc20:phospho-apc/c mediated degradation of cyclin a
    (R-DME-174184)
  • Cell cycle
    (R-DME-1640170)
  • Cell cycle, mitotic
    (R-DME-69278)
  • Cell cycle checkpoints
    (R-DME-69620)
  • Inactivation of apc/c via direct inhibition of the apc/c complex
    (R-DME-141430)
  • Inhibition of the proteolytic activity of apc/c required for the onset of anaphase by mitotic spindle checkpoint components
    (R-DME-141405)
  • Mitotic spindle checkpoint
    (R-DME-69618)
  • Regulation of apc/c activators between g1/s and early anaphase
    (R-DME-176408)
  • Regulation of mitotic cell cycle
    (R-DME-453276)
  • Bub1-bub3 complex
    (GO:1990298)
  • Kinetochore
    (GO:0000776)
  • Mitotic checkpoint complex
    (GO:0033597)
  • Mitotic spindle assembly checkpoint signaling
    (GO:0007094)
  • Nucleoplasm
    (GO:0005654)
  • Regulation of chromosome separation
    (GO:1905818)
  • Ubiquitin binding
    (GO:0043130)

Other Information

Genular Protein ID: 1906745085

Symbol: Q9VAJ2_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VAJ2

Database IDs:

AGR 1 ARBA 5 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 6 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 2 GO 7 Gene3D 1 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 Proteomes 2 Reactome 4 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 326
  • Mass: 37415
  • Checksum: 89EC16E18E5A9E9F
  • Sequence:
    • MRPPEFKLNN PPEDLISAVK FGPKSNQYMA ASSWDGTLRF YDVPANQLRQ KFVQDAPLLD 
CAFMDIVHVV SGSLDNQLRL FDVNTQAESI IGAHEEPIRC VEHAEYVNGI LTGSWDNTVK 
LWDMREKRCV GTFEQNNGKV YSMSVIDEKI VVATSDRKVL IWDLRKMDSY IMKRESSLKY 
QTRCIRLFPN KEGYVMSSIE GRVAVEYLDH DPEVQRRKFA FKCHRNREQN IEQIYPVNAL 
SFHNVYQTFA TGGSDGIVNI WDGFNKKRLC QFHEYDTSIS TLNFSSDGSA LAIGCSYLDQ 
LPETPATVPH PAIYIRYPTD QETKQK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.