Drice | FBgn0019972 | NCBI 43514

Details for: Drice

Gene ID: 43514

Symbol: Drice

Ensembl ID: FBgn0019972

Description: Death related ICE-like caspase

Associated with

Activation of caspases through apoptosome-mediated cleavage
(R-DME-111459)
Akt phosphorylates targets in the cytosol
(R-DME-198323)
Apoptosis
(R-DME-109581)
Apoptosis induced dna fragmentation
(R-DME-140342)
Apoptotic cleavage of cell adhesion proteins
(R-DME-351906)
Apoptotic cleavage of cellular proteins
(R-DME-111465)
Apoptotic execution phase
(R-DME-75153)
Apoptotic factor-mediated response
(R-DME-111471)
Caspase-mediated cleavage of cytoskeletal proteins
(R-DME-264870)
Caspase activation via dependence receptors in the absence of ligand
(R-DME-418889)
Caspase activation via extrinsic apoptotic signalling pathway
(R-DME-5357769)
Cytochrome c-mediated apoptotic response
(R-DME-111461)
Death receptor signaling
(R-DME-73887)
Formation of apoptosome
(R-DME-111458)
Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Intracellular signaling by second messengers
(R-DME-9006925)
Intrinsic pathway for apoptosis
(R-DME-109606)
Pip3 activates akt signaling
(R-DME-1257604)
Regulation of the apoptosome activity
(R-DME-9627069)
Regulation of tnfr1 signaling
(R-DME-5357905)
Rna polymerase ii transcription
(R-DME-73857)
Signaling by hippo
(R-DME-2028269)
Signal transduction
(R-DME-162582)
Smac, xiap-regulated apoptotic response
(R-DME-111469)
Tnf signaling
(R-DME-75893)
Tp53 regulates transcription of caspase activators and caspases
(R-DME-6803207)
Tp53 regulates transcription of cell death genes
(R-DME-5633008)
Transcriptional regulation by tp53
(R-DME-3700989)
Apoptotic process
(GO:0006915)
Bir domain binding
(GO:1990525)
Cysteine-type endopeptidase activity
(GO:0004197)
Cysteine-type endopeptidase activity involved in apoptotic process
(GO:0097153)
Cysteine-type endopeptidase activity involved in execution phase of apoptosis
(GO:0097200)
Cysteine-type peptidase activity
(GO:0008234)
Cytoplasm
(GO:0005737)
Negative regulation of peptidoglycan recognition protein signaling pathway
(GO:0061060)
Negative regulation of toll signaling pathway
(GO:0045751)
Neuron remodeling
(GO:0016322)
Nucleus
(GO:0005634)
Nurse cell apoptotic process
(GO:0045476)
Plasma membrane
(GO:0005886)
Positive regulation of compound eye retinal cell programmed cell death
(GO:0046672)
Positive regulation of neuron apoptotic process
(GO:0043525)
Programmed cell death
(GO:0012501)
Programmed cell death involved in cell development
(GO:0010623)
Proteolysis
(GO:0006508)
Response to x-ray
(GO:0010165)
Salivary gland histolysis
(GO:0035070)
Spermatid differentiation
(GO:0048515)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

Caspase

Genular Protein ID: 410217919

Symbol: DRICE_DROME

Name: Caspase

UniProtKB Accession Codes:

O01382 Q9VAH1

Database IDs:

Citations:

PubMed ID: 9184225

Title: Identification of a Drosophila melanogaster ICE/CED-3-related protease, drICE.

PubMed ID: 9184225

DOI: 10.1093/emboj/16.10.2805

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 10675329

Title: The Drosophila caspase DRONC is regulated by DIAP1.

PubMed ID: 10675329

DOI: 10.1093/emboj/19.4.598

PubMed ID: 18166655

Title: DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells.

PubMed ID: 18166655

DOI: 10.1083/jcb.200706027

Sequence Information:

Length: 339
Mass: 37363
Checksum: E105ED29518507EC
Sequence:

MDATNNGESA DQVGIRVGNP EQPNDHTDAL GSVGSGGAGS SGLVAGSSHP YGSGAIGQLA 
NGYSSPSSSY RKNVAKMVTD RHAAEYNMRH KNRGMALIFN HEHFEVPTLK SRAGTNVDCE 
NLTRVLKQLD FEVTVYKDCR YKDILRTIEY AASQNHSDSD CILVAILSHG EMGYIYAKDT 
QYKLDNIWSF FTANHCPSLA GKPKLFFIQA CQGDRLDGGV TMQRSQTETD GDSSMSYKIP 
VHADFLIAYS TVPGFYSWRN TTRGSWFMQS LCAELAANGK RLDILTLLTF VCQRVAVDFE 
SCTPDTPEMH QQKQIPCITT MLTRILRFSD KQLAPAGRV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Drice

Associated with

Other Information

Identification of a Drosophila melanogaster ICE/CED-3-related protease, drICE. PubMed ID: 9184225

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

The Drosophila caspase DRONC is regulated by DIAP1. PubMed ID: 10675329