wts | FBgn0011739 | NCBI 43651

Details for: wts

Gene ID: 43651

Symbol: wts

Ensembl ID: FBgn0011739

Description: warts

Associated with

Adherens junction
(GO:0005912)
Apicomedial cortex
(GO:0106037)
Atp binding
(GO:0005524)
Border follicle cell migration
(GO:0007298)
Cell-cell junction
(GO:0005911)
Cell fate specification
(GO:0001708)
Cytosol
(GO:0005829)
G1/s transition of mitotic cell cycle
(GO:0000082)
Hippo signaling
(GO:0035329)
Imaginal disc growth
(GO:0007446)
Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
(GO:0042771)
Negative regulation of canonical wnt signaling pathway
(GO:0090090)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of glial cell proliferation
(GO:0060253)
Negative regulation of imaginal disc growth
(GO:0045571)
Negative regulation of neuroblast proliferation
(GO:0007406)
Negative regulation of protein import into nucleus
(GO:0042308)
Open tracheal system development
(GO:0007424)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of lipophagy
(GO:1904504)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein serine/threonine kinase activity
(GO:0004674)
R8 cell development
(GO:0045463)
R8 cell fate specification
(GO:0045464)
Regulation of cell shape
(GO:0008360)
Regulation of dendrite morphogenesis
(GO:0048814)
Regulation of organ growth
(GO:0046620)
Response to ionizing radiation
(GO:0010212)
Stem cell proliferation
(GO:0072089)

Other Information

Proteins

Serine/threonine-protein kinase Warts

Genular Protein ID: 4289989957

Symbol: WARTS_DROME

Name: Serine/threonine-protein kinase Warts

UniProtKB Accession Codes:

Q9VA38

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 16096061

Title: The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP.

PubMed ID: 16096061

DOI: 10.1016/j.cell.2005.06.007

PubMed ID: 18818081

Title: Warts is required for PI3K-regulated growth arrest, autophagy, and autophagic cell death in Drosophila.

PubMed ID: 18818081

DOI: 10.1016/j.cub.2008.08.052

PubMed ID: 18256197

Title: In vivo regulation of Yorkie phosphorylation and localization.

PubMed ID: 18256197

DOI: 10.1242/dev.015255

PubMed ID: 18245354

Title: The mob as tumor suppressor gene is essential for early development and regulates tissue growth in Drosophila.

PubMed ID: 18245354

DOI: 10.1534/genetics.107.081570

PubMed ID: 20303269

Title: Ajuba LIM proteins are negative regulators of the Hippo signaling pathway.

PubMed ID: 20303269

DOI: 10.1016/j.cub.2010.02.035

Sequence Information:

Length: 1105
Mass: 122488
Checksum: 7D09D7AA9BA1A856
Sequence:

MHPAGEKRGG RPNDKYTAEA LESIKQDLTR FEVQNNHRNN QNYTPLRYTA TNGRNDALTP 
DYHHAKQPME PPPSASPAPD VVIPPPPAIV GQPGAGSISV SGVGVGVVGV ANGRVPKMMT 
ALMPNKLIRK PSIERDTASS HYLRCSPALD SGAGSSRSDS PHSHHTHQPS SRTVGNPGGN 
GGFSPSPSGF SEVAPPAPPP RNPTACSAAT PPPPVPPTSQ AYVKRRSPAL NNRPPAIAPP 
TQRGNSPVIT QNGLKNPQQQ LTQQLKSLNL YPGGGSGAVV EPPPPYLIQG GAGGAAPPPP 
PPSYTASMQS RQSPTQSQQS DYRKSPSSGI YSATSAGSPS PITVSLPPAP LAKPQPRVYQ 
ARSQQPIIMQ SVKSTQVQKP VLQTAVAPQS PSSASASNSP VHVLAAPPSY PQKSAAVVQQ 
QQQAAAAAHQ QQHQHQQSKP PTPTTPPLVG LNSKPNCLEP PSYAKSMQAK AATVVQQQQQ 
QQQQQQQVQQ QQVQQQQQQQ QQQLQALRVL QAQAQRERDQ RERDQRERER DQQKLANGNP 
GRQMLPPPPY QSNNNNNSEI KPPSCNNNNI QISNSNLATT PPIPPAKYNN NSSNTGANSS 
GGSNGSTGTT ASSSTSCKKI KHASPIPERK KISKEKEEER KEFRIRQYSP QAFKFFMEQH 
IENVIKSYRQ RTYRKNQLEK EMHKVGLPDQ TQIEMRKMLN QKESNYIRLK RAKMDKSMFV 
KLKPIGVGAF GEVTLVSKID TSNHLYAMKT LRKADVLKRN QVAHVKAERD ILAEADNNWV 
VKLYYSFQDK DNLYFVMDYI PGGDLMSLLI KLGIFEEELA RFYIAEVTCA VDSVHKMGFI 
HRDIKPDNIL IDRDGHIKLT DFGLCTGFRW THNSKYYQEN GNHSRQDSME PWEEYSENGP 
KPTVLERRRM RDHQRVLAHS LVGTPNYIAP EVLERSGYTQ LCDYWSVGVI LYEMLVGQPP 
FLANSPLETQ QKVINWEKTL HIPPQAELSR EATDLIRRLC ASADKRLGKS VDEVKSHDFF 
KGIDFADMRK QKAPYIPEIK HPTDTSNFDP VDPEKLRSND STMSSGDDVD QNDRTFHGFF 
EFTFRRFFDD KQPPDMTDDQ APVYV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: wts

Associated with

Other Information

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. PubMed ID: 16096061

Warts is required for PI3K-regulated growth arrest, autophagy, and autophagic cell death in Drosophila. PubMed ID: 18818081

In vivo regulation of Yorkie phosphorylation and localization. PubMed ID: 18256197

The mob as tumor suppressor gene is essential for early development and regulates tissue growth in Drosophila. PubMed ID: 18245354

Ajuba LIM proteins are negative regulators of the Hippo signaling pathway. PubMed ID: 20303269