pHCl 2 | FBgn0039840 | NCBI 43703

Details for: pHCl 2

Gene ID: 43703

Symbol: pHCl 2

Ensembl ID: FBgn0039840

Description: pH-sensitive chloride channel 2

Associated with

Neuronal system
(R-DME-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-DME-112314)
Transmission across chemical synapses
(R-DME-112315)
Apical plasma membrane
(GO:0016324)
Brush border membrane
(GO:0031526)
Cellular response to zinc ion
(GO:0071294)
Chemical synaptic transmission
(GO:0007268)
Chloride channel activity
(GO:0005254)
Chloride transmembrane transport
(GO:1902476)
Excitatory extracellular ligand-gated monoatomic ion channel activity
(GO:0005231)
Extracellular ligand-gated monoatomic ion channel activity
(GO:0005230)
Late endosome membrane
(GO:0031902)
Lysosomal membrane
(GO:0005765)
Membrane
(GO:0016020)
Monoatomic ion transmembrane transport
(GO:0034220)
Neuron projection
(GO:0043005)
Neurotransmitter receptor activity
(GO:0030594)
Ph-gated chloride channel activity
(GO:0061797)
Plasma membrane
(GO:0005886)
Positive regulation of insulin-like growth factor receptor signaling pathway
(GO:0043568)
Positive regulation of torc1 signaling
(GO:1904263)
Regulation of membrane potential
(GO:0042391)
Regulation of renal water transport
(GO:2001151)
Synapse
(GO:0045202)
Transmembrane signaling receptor activity
(GO:0004888)
Transmembrane transporter complex
(GO:1902495)
Zinc ion sensor activity
(GO:0106219)

Other Information

Proteins

PHCL2_DROME

Genular Protein ID: 3742446827

Symbol: PHCL2_DROME

Name: N/A

UniProtKB Accession Codes:

Q9V9Y4 E3CTP9

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 27172217

Title: Evolution, Expression, and Function of Nonneuronal Ligand-Gated Chloride Channels in Drosophila melanogaster.

PubMed ID: 27172217

DOI: 10.1534/g3.116.029546

PubMed ID: 27358471

Title: The orphan pentameric ligand-gated ion channel pHCl-2 is gated by pH and regulates fluid secretion in Drosophila Malpighian tubules.

PubMed ID: 27358471

DOI: 10.1242/jeb.141069

PubMed ID: 32269334

Title: An intestinal zinc sensor regulates food intake and developmental growth.

PubMed ID: 32269334

DOI: 10.1038/s41586-020-2111-5

Sequence Information:

Length: 526
Mass: 59826
Checksum: BC78EC5EC219F596
Sequence:

MDTLGIFVLI SYLGLSSAAG VHLGDLQQNL AANGSVVVSP LNTTDAFSVS INLSQSTVNN 
CPSLKNAESM ALMELLTRLT APCRYDRMVP PVVHNKDGEE VPMDIYARFY IYVMKNLDSS 
DLQFTVQGLL QLRYLDPRLA FSSYLPNRRQ PIMGESELKK MLWVPHIFLT NEQASTVLGT 
SAKDELTSIY PNGTVLTSTR LQATLYCWMN FQKFPFDEQK CKTTLESWMY NTTLVQLHWE 
TDNPVSFDKQ LQLTEYNLIG SLYNESIRVS NESYMSHGSL EGNYSIISFT VLLTREVGYY 
VIDYFLPSIM IVTISWVSFW LQADQTPART TLGCTTLLSF ITLSLSQENN LMKVSYVTMS 
EVWFLVCTIF IFGSLVEFAF VNTIWRRNND LQLKKRTTKY IVKSTFVPHL KKHRRHGYRR 
TDSTMSTMST TSMDKTCGPN NTVITIETPI IIGGSLSRED SAISLDEQDE TSTSESSDSS 
KEKPAQTFAT MTPKEVSLWI DRKMRFVFPL SFIVFNALFW TLVYCL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: pHCl 2

Associated with

Other Information

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

Evolution, Expression, and Function of Nonneuronal Ligand-Gated Chloride Channels in Drosophila melanogaster. PubMed ID: 27172217