Associated with
Other Information
Genular Protein ID: 868973686
Symbol: GAWKY_DROME
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10731132
Title: The genome sequence of Drosophila melanogaster.
PubMed ID: 10731132
PubMed ID: 12537572
Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.
PubMed ID: 12537572
PubMed ID: 12537569
Title: A Drosophila full-length cDNA resource.
PubMed ID: 12537569
PubMed ID: 16177138
Title: A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing.
PubMed ID: 16177138
DOI: 10.1261/rna.2191905
PubMed ID: 16815998
Title: mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes.
PubMed ID: 16815998
DOI: 10.1101/gad.1424106
PubMed ID: 16880270
Title: Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.
PubMed ID: 16880270
PubMed ID: 18345015
Title: GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay.
PubMed ID: 18345015
DOI: 10.1038/nsmb.1405
PubMed ID: 19797087
Title: The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release.
PubMed ID: 19797087
DOI: 10.1128/mcb.01081-09
PubMed ID: 19304924
Title: Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila.
PubMed ID: 19304924
DOI: 10.1261/rna.1364909
PubMed ID: 19451544
Title: Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway.
PubMed ID: 19451544
DOI: 10.1261/rna.1541209
PubMed ID: 19383769
Title: A C-terminal silencing domain in GW182 is essential for miRNA function.
PubMed ID: 19383769
DOI: 10.1261/rna.1605509
PubMed ID: 20530530
Title: The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression.
PubMed ID: 20530530
DOI: 10.1093/nar/gkq501
PubMed ID: 21981923
Title: GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.
PubMed ID: 21981923
PubMed ID: 19295135
Title: The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing.
PubMed ID: 19295135
DOI: 10.1093/nar/gkp173
Sequence Information:
- Length: 1384
- Mass: 142973
- Checksum: 4E87DFE49050883E
- Sequence:
MREALFSQDG WGCQHVNQDT NWEVPSSPEP ANKDAPGPPM WKPSINNGTD LWESNLRNGG QPAAQQVPKP SWGHTPSSNL GGTWGEDDDG ADSSSVWTGG AVSNAGSGAA VGVNQAGVNV GPGGVVSSGG PQWGQGVVGV GLGSTGGNGS SNITGSSGVA TGSSGNSSNA GNGWGDPREI RPLGVGGSMD IRNVEHRGGN GSGATSSDPR DIRMIDPRDP IRGDPRGISG RLNGTSEMWG HHPQMSHNQL QGINKMVGQS VATASTSVGT SGSGIGPGGP GPSTVSGNIP TQWGPAQPVS VGVSGPKDMS KQISGWEEPS PPPQRRSIPN YDDGTSLWGQ QTRVPAASGH WKDMTDSIGR SSHLMRGQSQ TGGIGIAGVG NSNVPVGANP SNPISSVVGP QARIPSVGGV QHKPDGGAMW VHSGNVGGRN NVAAVTTWGD DTHSVNVGAP SSGSVSSNNW VDDKSNSTLA QNSWSDPAPV GVSWGNKQSK PPSNSASSGW STAAGVVDGV DLGSEWNTHG GIIGKSQQQQ KLAGLNVGMV NVINAEIIKQ SKQYRILVEN GFKKEDVERA LVIANMNIEE AADMLRANSS LSMDGWRRHD ESLGSYADHN SSTSSGGFAG RYPVNSGQPS MSFPHNNLMN NMGGTAVTGG NNNTNMTALQ VQKYLNQGQH GVAVGPQAVG NSSAVSVGFG QNTSNAAVAG AASVNIAANT NNQPSGQQIR MLGQQIQLAI HSGFISSQIL TQPLTQTTLN LLNQLLSNIK HLQAAQQSLT RGGNVNPMAV NVAISKYKQQ IQNLQNQINA QQAVYVKQQN MQPTSQQQQP QQQQLPSVHL SNSGNDYLRG HDAINNLQSN FSELNINKPS GYQGASNQQS RLNQWKLPVL DKEINSDSTE FSRAPGATKQ NLTANTSNIN SLGLQNDSTW STGRSIGDGW PDPSSDNENK DWSVAQPTSA ATAYTDLVQE FEPGKPWKGS QIKSIEDDPS ITPGSVARSP LSINSTPKDA DIFANTGKNS PTDLPPLSLS SSTWSFNPNQ NYPSHSWSDN SQQCTATSEL WTSPLNKSSS RGPPPGLTAN SNKSANSNAS TPTTITGGAN GWLQPRSGGV QTTNTNWTGG NTTWGSSWLL LKNLTAQIDG PTLRTLCMQH GPLVSFHPYL NQGIALCKYT TREEANKAQM ALNNCVLANT TIFAESPSEN EVQSIMQHLP QTPSSTSSSG TSGGNVGGVG TSANNANSGS AACLSGNNSG NGNGSASGAG SGNNGNSSCN NSAAGGGSSS NNTITTVANS NLVGSSGSVS NSSGVTANSS TVSVVSCTAS GNSINGAGTA NSSGSKSSAN NLASGQSSAS NLTNSTNSTW RQTSQNQALQ SQSRPSGREA DFDYISLVYS IVDD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.