Details for: GET3

Gene ID: 439

Symbol: GET3

Ensembl ID: ENSG00000198356

Description: guided entry of tail-anchored proteins factor 3, ATPase

Associated with

Other Information

Genular Protein ID: 3076587774

Symbol: GET3_HUMAN

Name: Transmembrane domain recognition complex 40 kDa ATPase subunit

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8884272

Title: Isolation of the ATP-binding human homolog of the arsA component of the bacterial arsenite transporter.

PubMed ID: 8884272

DOI: 10.1006/geno.1996.0494

PubMed ID: 9712828

Title: Biochemical characterization of the human arsenite-stimulated ATPase (hASNA-I).

PubMed ID: 9712828

DOI: 10.1074/jbc.273.35.22173

PubMed ID: 9736449

Title: Dual cytoplasmic and nuclear distribution of the novel arsenite-stimulated human ATPase (hASNA-I).

PubMed ID: 9736449

DOI: 10.1002/(sici)1097-4644(19981001)71:1<1::aid-jcb1>3.3.co;2-r

PubMed ID: 9774623

Title: Immunohistochemical analysis of the distribution of the human ATPase (hASNA-I) in normal tissues and its overexpression in breast adenomas and carcinomas.

PubMed ID: 9774623

DOI: 10.1177/002215549804601104

PubMed ID: 17382883

Title: Identification of a targeting factor for posttranslational membrane protein insertion into the ER.

PubMed ID: 17382883

DOI: 10.1016/j.cell.2007.01.036

PubMed ID: 18477612

Title: Distinct targeting pathways for the membrane insertion of tail-anchored (TA) proteins.

PubMed ID: 18477612

DOI: 10.1242/jcs.020321

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21444755

Title: WRB is the receptor for TRC40/Asna1-mediated insertion of tail-anchored proteins into the ER membrane.

PubMed ID: 21444755

DOI: 10.1242/jcs.084277

PubMed ID: 23041287

Title: Molecular machinery for insertion of tail-anchored membrane proteins into the endoplasmic reticulum membrane in mammalian cells.

PubMed ID: 23041287

DOI: 10.1016/j.molcel.2012.08.028

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24392163

Title: WRB and CAML are necessary and sufficient to mediate tail-anchored protein targeting to the ER membrane.

PubMed ID: 24392163

DOI: 10.1371/journal.pone.0085033

PubMed ID: 25535373

Title: Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain.

PubMed ID: 25535373

DOI: 10.1073/pnas.1402745112

PubMed ID: 31461301

Title: Biallelic variants in ASNA1, encoding a cytosolic targeting factor of tail-anchored proteins, cause rapidly progressive pediatric cardiomyopathy.

PubMed ID: 31461301

DOI: 10.1161/circgen.119.002507

PubMed ID: 32910895

Title: Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex.

PubMed ID: 32910895

DOI: 10.1016/j.molcel.2020.08.012

Sequence Information:

  • Length: 348
  • Mass: 38793
  • Checksum: DA52C4ACC35C7A36
  • Sequence:
  • MAAGVAGWGV EAEEFEDAPD VEPLEPTLSN IIEQRSLKWI FVGGKGGVGK TTCSCSLAVQ 
    LSKGRESVLI ISTDPAHNIS DAFDQKFSKV PTKVKGYDNL FAMEIDPSLG VAELPDEFFE 
    EDNMLSMGKK MMQEAMSAFP GIDEAMSYAE VMRLVKGMNF SVVVFDTAPT GHTLRLLNFP 
    TIVERGLGRL MQIKNQISPF ISQMCNMLGL GDMNADQLAS KLEETLPVIR SVSEQFKDPE 
    QTTFICVCIA EFLSLYETER LIQELAKCKI DTHNIIVNQL VFPDPEKPCK MCEARHKIQA 
    KYLDQMEDLY EDFHIVKLPL LPHEVRGADK VNTFSALLLE PYKPPSAQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.