Details for: trbl

Gene ID: 43999

Symbol: trbl

Ensembl ID: FBgn0028978

Description: tribbles

Associated with

Other Information

Genular Protein ID: 2065320835

Symbol: TRIB_DROME

Name: N/A

UniProtKB Accession Codes:

Q9V3Z1

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 5 EnsemblMetazoa 1 FlyBase 2 GO 18 Gene3D 1 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 2 Reactome 5 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10837248

Title: Tribbles, a cell cycle brake that coordinates proliferation and morphogenesis during Drosophila gastrulation.

PubMed ID: 10837248

DOI: 10.1016/s0960-9822(00)00502-9

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10850493

Title: Tribbles coordinates mitosis and morphogenesis in Drosophila by regulating string/CDC25 proteolysis.

PubMed ID: 10850493

DOI: 10.1016/s0092-8674(00)80861-2

PubMed ID: 10850494

Title: A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila.

PubMed ID: 10850494

DOI: 10.1016/s0092-8674(00)80862-4

PubMed ID: 10949024

Title: The level of C/EBP protein is critical for cell migration during Drosophila oogenesis and is tightly controlled by regulated degradation.

PubMed ID: 10949024

DOI: 10.1016/s1097-2765(05)00008-0

PubMed ID: 15581871

Title: Mother-daughter precursor cell fate transformation after Cdc2 down-regulation in the Drosophila bristle lineage.

PubMed ID: 15581871

DOI: 10.1016/j.ydbio.2004.08.043

PubMed ID: 18430923

Title: Genetic dissociation of ethanol sensitivity and memory formation in Drosophila melanogaster.

PubMed ID: 18430923

DOI: 10.1534/genetics.107.084582

PubMed ID: 23290551

Title: Mechanism and regulation of Cdc25/Twine protein destruction in embryonic cell-cycle remodeling.

PubMed ID: 23290551

DOI: 10.1016/j.cub.2012.11.036

PubMed ID: 23305818

Title: The kinase domain of Drosophila Tribbles is required for turnover of fly C/EBP during cell migration.

PubMed ID: 23305818

DOI: 10.1016/j.ydbio.2012.12.016

PubMed ID: 25329475

Title: Drosophila tribbles antagonizes insulin signaling-mediated growth and metabolism via interactions with Akt kinase.

PubMed ID: 25329475

DOI: 10.1371/journal.pone.0109530

PubMed ID: 29025897

Title: A Drosophila model of insulin resistance associated with the human Trib3 Q/R polymorphism.

PubMed ID: 29025897

DOI: 10.1242/dmm.030619

PubMed ID: 28669782

Title: The Drosophila melanogaster tribbles pseudokinase is necessary for proper memory formation.

PubMed ID: 28669782

DOI: 10.1016/j.nlm.2017.06.006

Sequence Information:

  • Length: 484
  • Mass: 54077
  • Checksum: 3E3B1D3E5645B0D7
  • Sequence:
    • MDNSSGQNSR TASSASTSKI VNYSSPVSPG VAAATSSSSS SSSSGMSSSQ EDTVLGLFTP 
KKEFPNAKML QTIREKLMTP GGACDLLALG IAAEPTDQQP VKLIQQRYLI SAQPSHISAA 
VAAKTPASYR HLVDLTASNL RCVDIFTGEQ FLCRIVNEPL HKVQRAYFQL QQHDEELRRS 
TIYGHPLIRP VHDIIPLTKD RTYILIAPVP QERDSTGGVT GVYENLHTYI RHAKRLCETE 
ARAIFHQICQ TVQVCHRNGI ILRDLKLKRF YFIDEARTKL QYESLEGSMI LDGEDDTLSD 
KIGCPLYTAP ELLCPQQTYK GKPADMWSLG VILYTMLVGQ YPFYEKANCN LITVIRHGNV 
QIPLTLSKSV RWLLLSLLRK DYTERMTASH IFLTPWLREQ RPFHMYLPVD VEVAEDWSDA 
EEDEGTAADA MDDDEEGLCP LGDKHEYEDI GVEPLDYTRS TLQMAQNANG LSTEPEPDTD 
VDMG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.