MAPk Ak2 | FBgn0013987 | NCBI 44573

Details for: MAPk Ak2

Gene ID: 44573

Symbol: MAPk Ak2

Ensembl ID: FBgn0013987

Description: MAP kinase activated protein-kinase-2

Associated with

Activated tak1 mediates p38 mapk activation
(R-DME-450302)
Butyrate response factor 1 (brf1) binds and destabilizes mrna
(R-DME-450385)
Cellular responses to stimuli
(R-DME-8953897)
Cellular responses to stress
(R-DME-2262752)
Cellular response to heat stress
(R-DME-3371556)
Cellular senescence
(R-DME-2559583)
Creb phosphorylation
(R-DME-199920)
Cytokine signaling in immune system
(R-DME-1280215)
Immune system
(R-DME-168256)
Innate immune system
(R-DME-168249)
Interleukin-17 signaling
(R-DME-448424)
Map kinase activation
(R-DME-450294)
Mapk targets/ nuclear events mediated by map kinases
(R-DME-450282)
Metabolism of rna
(R-DME-8953854)
Myd88 cascade initiated on plasma membrane
(R-DME-975871)
Myd88 dependent cascade initiated on endosome
(R-DME-975155)
Myd88-independent tlr4 cascade
(R-DME-166166)
Myd88:mal(tirap) cascade initiated on plasma membrane
(R-DME-166058)
Nuclear events (kinase and transcription factor activation)
(R-DME-198725)
Oxidative stress induced senescence
(R-DME-2559580)
P38mapk events
(R-DME-171007)
Regulation of hsf1-mediated heat shock response
(R-DME-3371453)
Regulation of mrna stability by proteins that bind au-rich elements
(R-DME-450531)
Signaling by interleukins
(R-DME-449147)
Signaling by ntrk1 (trka)
(R-DME-187037)
Signaling by ntrks
(R-DME-166520)
Signaling by receptor tyrosine kinases
(R-DME-9006934)
Signaling by vegf
(R-DME-194138)
Signalling to erks
(R-DME-187687)
Signalling to ras
(R-DME-167044)
Signal transduction
(R-DME-162582)
Toll-like receptor cascades
(R-DME-168898)
Toll like receptor 2 (tlr2) cascade
(R-DME-181438)
Toll like receptor 3 (tlr3) cascade
(R-DME-168164)
Toll like receptor 4 (tlr4) cascade
(R-DME-166016)
Toll like receptor 5 (tlr5) cascade
(R-DME-168176)
Toll like receptor 7/8 (tlr7/8) cascade
(R-DME-168181)
Toll like receptor 9 (tlr9) cascade
(R-DME-168138)
Toll like receptor 10 (tlr10) cascade
(R-DME-168142)
Toll like receptor tlr1:tlr2 cascade
(R-DME-168179)
Toll like receptor tlr6:tlr2 cascade
(R-DME-168188)
Traf6 mediated induction of nfkb and map kinases upon tlr7/8 or 9 activation
(R-DME-975138)
Trif(ticam1)-mediated tlr4 signaling
(R-DME-937061)
Tristetraprolin (ttp, zfp36) binds and destabilizes mrna
(R-DME-450513)
Vegfa-vegfr2 pathway
(R-DME-4420097)
Atp binding
(GO:0005524)
Calcium-dependent protein serine/threonine kinase activity
(GO:0009931)
Calmodulin-dependent protein kinase activity
(GO:0004683)
Calmodulin binding
(GO:0005516)
Cytoplasm
(GO:0005737)
Intracellular signal transduction
(GO:0035556)
Mitogen-activated protein kinase binding
(GO:0051019)
Nucleus
(GO:0005634)
Peptidyl-serine phosphorylation
(GO:0018105)
Positive regulation of cell size
(GO:0045793)
Protein autophosphorylation
(GO:0046777)
Protein kinase activity
(GO:0004672)
Protein phosphorylation
(GO:0006468)
Regulation of jnk cascade
(GO:0046328)
Response to salt stress
(GO:0009651)

Other Information

Proteins

MAP kinase-activated protein kinase 2

Genular Protein ID: 3407718181

Symbol: MAPK2_DROME

Name: MAP kinase-activated protein kinase 2

UniProtKB Accession Codes:

P49071 Q9W480

Database IDs:

Citations:

PubMed ID: 7590268

Title: The Drosophila melanogaster homolog of the mammalian MAPK-activated protein kinase-2 (MAPKAPK-2) lacks a proline-rich N-terminus.

PubMed ID: 7590268

DOI: 10.1016/0378-1119(95)00279-f

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

Sequence Information:

Length: 359
Mass: 41401
Checksum: 69C5F9A94D1511EC
Sequence:

MLSLQNQRQP KTTPLTDDYV TSNTVLGYGI NGKVVQCTHR RTQQNYALKV LLDSERARRE 
VDLHWRVSGC RYIVNIIDVY ENTFKDRKCL LVVMECMEGG ELFQRIQDKA DGAFTEREAA 
QIMHEICAAV DYLHSRDIAH RDLKPENLLY TTTQPNATLK LTDFGFAKET FTSYTLQTPC 
YTPYYVAPEV LGPEKYDKSC DIWSLGVVMY IIMCGFPPFY SNHGLAISPG MKNRIRTGQY 
DFPDPEWTNV SQAAKDLIKG MLNVDPSKRL RIQDVISNKW IAQYNAVPQT PLCTGRMLKE 
AEETWPEVQE EMTRSLATMR VDYDQMQIKA LDKSNNPLLT KRRKKIEEME LYMANATRN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.