Details for: cwo

Gene ID: 44669

Symbol: cwo

Ensembl ID: FBgn0259938

Description: clockwork orange

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Circadian regulation of gene expression
    (GO:0032922)
  • Circadian rhythm
    (GO:0007623)
  • Dendrite morphogenesis
    (GO:0048813)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Peripheral nervous system development
    (GO:0007422)
  • Protein dimerization activity
    (GO:0046983)
  • Regulation of circadian rhythm
    (GO:0042752)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of neurogenesis
    (GO:0050767)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)

Other Information

Genular Protein ID: 2830485243

Symbol: CWO_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VGZ5 C8VV96 Q9U450

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 EMBL 5 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 15 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 2 Reactome 1 RefSeq 1 SAM 1 SMART 2 STRING 1 SUPFAM 2 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 11102367

Title: Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins.

PubMed ID: 11102367

DOI: 10.1093/genetics/156.4.1691

PubMed ID: 17555964

Title: Clockwork orange encodes a transcriptional repressor important for circadian-clock amplitude in Drosophila.

PubMed ID: 17555964

DOI: 10.1016/j.cub.2007.05.039

PubMed ID: 17578907

Title: Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component.

PubMed ID: 17578907

DOI: 10.1101/gad.1552607

PubMed ID: 17578908

Title: A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock.

PubMed ID: 17578908

DOI: 10.1101/gad.1552207

PubMed ID: 18375860

Title: The clockwork orange Drosophila protein functions as both an activator and a repressor of clock gene expression.

PubMed ID: 18375860

DOI: 10.1177/0748730407313817

PubMed ID: 27814361

Title: CLOCKWORK ORANGE enhances PERIOD mediated rhythms in transcriptional repression by antagonizing E-box binding by CLOCK-CYCLE.

PubMed ID: 27814361

DOI: 10.1371/journal.pgen.1006430

Sequence Information:

  • Length: 698
  • Mass: 75106
  • Checksum: 028BDB435ABA8683
  • Sequence:
    • MEPYWNETNG HAAHPVKYES EAAVSSFPYC TESSLNFSTS ATAYSEDDAE YATGRRNKTS 
RQDPLSHRII EKRRRDRMNS CLADLSRLIP PQYQRKGRGR IEKTEIIEMA IRHLKHLQSE 
CQQKESDYRS GYMDCMKEAA KFLYDVHMQD FCHRLLGRLQ EHIDEMFKTD CYKSTRSCHM 
PDNVSASSGS PHQAYHPPLC HLRDMLATSA SDVEHSQDHN DVKDLSFRNH LNQLQRSQQA 
AAAAAVAAAA VAVANGSSPA SNAGVDSKVP LTNGGGTGGA PPAADNVPSN STGSGSAAAC 
AGGNSNSSGS NSSNAASSTI CPPAGGSCPA KVTPLAAHQQ PHQAPVITST APHHHHHHTD 
SSHHDFESSR EPILHTDTSN MHSPPPRDLL LQQHPHLAHS HHTQDSLMSV RMRNYSESSH 
EIEHNNNYKY KNHIKERFVH ELHDEETSSE HCPVAAHLQS DHSHLQALSE HSKDGTEPEI 
APIMAKKRKL AEAAANGEIP LEVHTESSNA GASSANRLDK PSPSFNFSDI KDIKAELHNG 
NSNSSPLLAK LSAVAAAGGQ LSTPSSTTAP LPPRHTFTVP IFALHGQGNY YVPLNVDYNA 
LVPFLNGMDL LEKSYTSMPV VHPININVNF MPSSPSASLL AAAAAAAVAV GKQQQQQAVV 
AAGAGLPLST NSAAAQAAAV AAAAVAKAKL EQAMNQSW

Genular Protein ID: 2934967058

Symbol: Q8MRI9_DROME

Name: N/A

UniProtKB Accession Codes:

Q8MRI9

Database IDs:

AGR 1 ARBA 2 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 EMBL 6 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 2 GO 4 Gene3D 1 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InterPro 3 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 2 SAM 1 SMART 1 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 621
  • Mass: 66253
  • Checksum: 95F4BBDBE8544446
  • Sequence:
    • MNSCLADLSR LIPPQYQRKG RGRIEKTEII EMAIRHLKHL QSECQQKESD YRSGYMDCMK 
EAAKFLYDVH MQDFCHRLLG RLQEHIDEMF KTDCYKSTRS CHMPDNVSAS SGSPHQAYHP 
PLCHLRDMLA TSASDVEHSQ DHNDVKDLSF RNHLNQLQRS QQAAAAAAVA AAAVAVANGS 
SPASNAGVDS KVPLTNGGGT GGAPPAADNV PSNSTGSGSA AACAGGNSNS SGSNSSNAAS 
STICPPAGGS CPAKVTPLAA HQQPHQAPVI TSTAPHHHHH HTDSSHHDFE SSREPILHTD 
TSNMHSPPPR DLLLQQHPHL AHSHHTQDSL MSVRMRNYSE SSHEIEHNNN YKYKNHIKER 
FVHELHDEET SSEHCPVAAH LQSDHSHLQA LSEHSKDGTE PEIAPIMAKK RKLAEAAANG 
EIPLEVHTES SNAGASSANR LDKPSPSFNF SDIKDIKAEL HNGNSNSSPL LAKLSAVAAA 
GGQLSTPSST TAPLPPRHTF TVPIFALHGQ GNYYVPLNVD YNALVPFLNG MDLLEKSYTS 
MPVVHPININ VNFMPSSPSA SLLAAAAAAA VAVGKQQQQQ AVVAAGAGLP LSTNSAAAQA 
AAVAAAAVAK AKLEQAMNQS W

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.