Details for: ASS1P9

Gene ID: 454

Symbol: ASS1P9

Ensembl ID: ENSG00000217791

Description: argininosuccinate synthetase 1 pseudogene 9

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.2390
    Cell Significance Index: 2.4400
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.0357
    Cell Significance Index: 0.3400
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: 0.0055
    Cell Significance Index: 0.0600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0050
    Cell Significance Index: 0.1500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0003
    Cell Significance Index: 0.0700
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0017
    Cell Significance Index: -0.0300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0019
    Cell Significance Index: -0.0600
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0019
    Cell Significance Index: -0.0200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0021
    Cell Significance Index: -0.0400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0024
    Cell Significance Index: -0.0500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0029
    Cell Significance Index: -0.0600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0031
    Cell Significance Index: -0.0600
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0043
    Cell Significance Index: -0.0300
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.0060
    Cell Significance Index: -0.0400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0103
    Cell Significance Index: -0.2800
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: -0.0274
    Cell Significance Index: -0.2800
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0349
    Cell Significance Index: -0.3400
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0368
    Cell Significance Index: -0.5100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0469
    Cell Significance Index: -2.1900
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0575
    Cell Significance Index: -0.5400
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.1218
    Cell Significance Index: -1.6700
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: -0.1231
    Cell Significance Index: -1.3400
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1239
    Cell Significance Index: -1.3500
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.1245
    Cell Significance Index: -1.5300
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.1274
    Cell Significance Index: -1.6600
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: -0.1385
    Cell Significance Index: -1.4800
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.1441
    Cell Significance Index: -1.5200
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.1466
    Cell Significance Index: -1.5900
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.1499
    Cell Significance Index: -1.5900
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.1525
    Cell Significance Index: -1.5800
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1767
    Cell Significance Index: -1.6700
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.1770
    Cell Significance Index: -1.4600
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.1829
    Cell Significance Index: -2.0300
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.2021
    Cell Significance Index: -1.2700
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.2061
    Cell Significance Index: -1.5900
  • Cell Name: kidney loop of Henle epithelial cell (CL1000909)
    Fold Change: -0.2311
    Cell Significance Index: -2.1500
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.2414
    Cell Significance Index: -1.5000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Pseudogenic nature:** ASS1P9 is a non-coding pseudogene, meaning it lacks the coding potential to produce a functional protein. 2. **Wide tissue expression:** ASS1P9 is significantly expressed in various cell types, including plasma cells, epithelial cells, mesenchymal stem cells, and endothelial cells. 3. **Ensembl ID:** ASS1P9 has an Ensembl ID of ENSG00000217791, indicating its existence in the Ensembl database, a comprehensive resource for gene annotation and expression data. **Pathways and Functions:** While ASS1P9 is a pseudogene, its expression in various cell types suggests that it may be involved in regulating gene expression, cellular differentiation, or immune responses. Several potential pathways have been proposed, including: 1. **Immunomodulation:** ASS1P9 may play a role in modulating immune responses, particularly in plasma cells, which are crucial for antibody production. 2. **Cellular differentiation:** ASS1P9 may influence cellular differentiation processes, such as the development of endothelial cells or mesenchymal stem cells. 3. **Gene expression regulation:** ASS1P9 may act as a regulator of gene expression, influencing the expression of other genes in various cell types. **Clinical Significance:** The clinical significance of ASS1P9 remains unclear, but its widespread tissue expression raises several possibilities: 1. **Cancer association:** ASS1P9 may be involved in cancer development or progression, particularly in tissues with high expression levels, such as the kidney or mammary gland. 2. **Inflammatory disorders:** ASS1P9 may play a role in inflammatory disorders, such as autoimmune diseases or allergies, where immune responses are dysregulated. 3. **Immunodeficiency:** ASS1P9 may be associated with immunodeficiency disorders, where the immune system is compromised, leading to increased susceptibility to infections. In conclusion, ASS1P9 is a pseudogene with wide tissue expression, which raises questions about its potential functions and clinical significance. Further research is needed to elucidate the role of ASS1P9 in various biological processes and its clinical implications.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.