Details for: eIF4E1
Associated with
Other Information
Genular Protein ID: 352912200
Symbol: IF4E_DROME
Name: Eukaryotic translation initiation factor 4E1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7742371
Title: Translation initiation factor eIF-4E from Drosophila: cDNA sequence and expression of the gene.
PubMed ID: 7742371
PubMed ID: 8663200
Title: Alternatively spliced transcripts from the Drosophila eIF4E gene produce two different Cap-binding proteins.
PubMed ID: 8663200
PubMed ID: 9065696
Title: Localization, structure and expression of the gene for translation initiation factor eIF-4E from Drosophila melanogaster.
PubMed ID: 9065696
PubMed ID: 10731132
Title: The genome sequence of Drosophila melanogaster.
PubMed ID: 10731132
PubMed ID: 12537572
Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.
PubMed ID: 12537572
PubMed ID: 12537569
Title: A Drosophila full-length cDNA resource.
PubMed ID: 12537569
PubMed ID: 11500381
Title: PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.
PubMed ID: 11500381
PubMed ID: 11389445
Title: The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila.
PubMed ID: 11389445
DOI: 10.1038/35078571
PubMed ID: 14691132
Title: Cup is an eIF4E binding protein required for both the translational repression of oskar and the recruitment of Barentsz.
PubMed ID: 14691132
PubMed ID: 14645523
Title: Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster.
PubMed ID: 14645523
PubMed ID: 14723848
Title: Drosophila Cup is an eIF4E binding protein that associates with Bruno and regulates oskar mRNA translation in oogenesis.
PubMed ID: 14723848
PubMed ID: 14685270
Title: Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression.
PubMed ID: 14685270
PubMed ID: 17178403
Title: Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies.
PubMed ID: 17178403
PubMed ID: 20869429
Title: Diminution of eIF4E activity suppresses parkin mutant phenotypes.
PubMed ID: 20869429
PubMed ID: 23716590
Title: Mextli is a novel eukaryotic translation initiation factor 4E-binding protein that promotes translation in Drosophila melanogaster.
PubMed ID: 23716590
DOI: 10.1128/mcb.01354-12
PubMed ID: 28875934
Title: ME31B globally represses maternal mRNAs by two distinct mechanisms during the Drosophila maternal-to-zygotic transition.
PubMed ID: 28875934
DOI: 10.7554/elife.27891
PubMed ID: 22832024
Title: Crystal structure of a minimal eIF4E-Cup complex reveals a general mechanism of eIF4E regulation in translational repression.
PubMed ID: 22832024
PubMed ID: 26294658
Title: Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation.
PubMed ID: 26294658
PubMed ID: 25702871
Title: Molecular architecture of 4E-BP translational inhibitors bound to eIF4E.
PubMed ID: 25702871
Sequence Information:
- Length: 259
- Mass: 29224
- Checksum: B844B2DD5738758E
- Sequence:
MQSDFHRMKN FANPKSMFKT SAPSTEQGRP EPPTSAAAPA EAKDVKPKED PQETGEPAGN TATTTAPAGD DAVRTEHLYK HPLMNVWTLW YLENDRSKSW EDMQNEITSF DTVEDFWSLY NHIKPPSEIK LGSDYSLFKK NIRPMWEDAA NKQGGRWVIT LNKSSKTDLD NLWLDVLLCL IGEAFDHSDQ ICGAVINIRG KSNKISIWTA DGNNEEAALE IGHKLRDALR LGRNNSLQYQ LHKDTMVKQG SNVKSIYTL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.