Details for: eIF3h

Gene ID: 45682

Symbol: eIF3h

Ensembl ID: FBgn0022023

Description: eukaryotic translation initiation factor 3 subunit h

Associated with

  • Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
    (R-DME-72662)
  • Cap-dependent translation initiation
    (R-DME-72737)
  • Eukaryotic translation initiation
    (R-DME-72613)
  • Formation of a pool of free 40s subunits
    (R-DME-72689)
  • Formation of the ternary complex, and subsequently, the 43s complex
    (R-DME-72695)
  • L13a-mediated translational silencing of ceruloplasmin expression
    (R-DME-156827)
  • Metabolism of proteins
    (R-DME-392499)
  • Ribosomal scanning and start codon recognition
    (R-DME-72702)
  • Translation
    (R-DME-72766)
  • Translation initiation complex formation
    (R-DME-72649)
  • Cytoplasm
    (GO:0005737)
  • Cytosol
    (GO:0005829)
  • Eukaryotic 43s preinitiation complex
    (GO:0016282)
  • Eukaryotic translation initiation factor 3 complex
    (GO:0005852)
  • Metal-dependent deubiquitinase activity
    (GO:0140492)
  • Metallopeptidase activity
    (GO:0008237)
  • Negative regulation of proteasomal ubiquitin-dependent protein catabolic process
    (GO:0032435)
  • Peptidase activity
    (GO:0008233)
  • Positive regulation of notch signaling pathway
    (GO:0045747)
  • Translational initiation
    (GO:0006413)
  • Translation initiation factor activity
    (GO:0003743)

Other Information

Genular Protein ID: 1505244169

Symbol: EIF3H_DROME

Name: N/A

UniProtKB Accession Codes:

Q9U9Q4 C0PTU9 Q7KLX2 Q9VMU9

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 EnsemblMetazoa 2 FlyBase 1 GO 12 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HAMAP 1 HAMAP-Rule 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 Reactome 5 RefSeq 2 SMART 1 SMR 1 STRING 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 23716590

Title: Mextli is a novel eukaryotic translation initiation factor 4E-binding protein that promotes translation in Drosophila melanogaster.

PubMed ID: 23716590

DOI: 10.1128/mcb.01354-12

Sequence Information:

  • Length: 338
  • Mass: 38408
  • Checksum: 76E375DCC2FDA732
  • Sequence:
    • MANRANRHAA RTEDSDNTIN YVQCDGLAVM KMVKHCHEES SNMDLAQGAL LGLVVDKCLE 
ITNCFPFPKS GDETMDEEMY QLTVMRRLRR VNVDHLHVGW YQSSDVGNSL SMALLESQYH 
YQTSIEESVV VVYDTQKSSR GFLCLKAYRL TPQAIQMYKD GDFTPEAFRT LKVGYENLFA 
EIPIVIKNSP LTNIMMSELN ELLPEDKGHN FLDLGTATVL ENQMRSLIER VDELYQEAVR 
YNKYQQVVFK QDTEKHRALA KLAAENAVRT SKGEPTVPEE EVIKQFRPMT APNRLTATIT 
SGQINTHAQH IAQFCSQSLA KLFITESLQI AKEAKETK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.