Details for: Spn27A

Gene ID: 45815

Symbol: Spn27A

Ensembl ID: FBgn0028990

Description: Serpin 27A

Associated with

Other Information

Genular Protein ID: 3457712982

Symbol: SP27A_DROME

Name: N/A

UniProtKB Accession Codes:

Q9V3N1

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 8 EnsemblMetazoa 2 FlyBase 2 GO 15 Gene3D 2 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 2 Reactome 10 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12408809

Title: An immune-responsive Serpin regulates the melanization cascade in Drosophila.

PubMed ID: 12408809

DOI: 10.1016/s1534-5807(02)00267-8

PubMed ID: 12456640

Title: A serpin mutant links Toll activation to melanization in the host defence of Drosophila.

PubMed ID: 12456640

DOI: 10.1093/emboj/cdf661

PubMed ID: 14654000

Title: A serpin regulates dorsal-ventral axis formation in the Drosophila embryo.

PubMed ID: 14654000

DOI: 10.1016/j.cub.2003.10.062

PubMed ID: 14667416

Title: Spatial regulation of developmental signaling by a serpin.

PubMed ID: 14667416

DOI: 10.1016/s1534-5807(03)00338-1

PubMed ID: 15749104

Title: Drosophila serpin 27A is a likely target for immune suppression of the blood cell-mediated melanotic encapsulation response.

PubMed ID: 15749104

DOI: 10.1016/j.jinsphys.2004.10.013

PubMed ID: 16861233

Title: Two proteases defining a melanization cascade in the immune system of Drosophila.

PubMed ID: 16861233

DOI: 10.1074/jbc.m601642200

PubMed ID: 16322759

Title: Prophenoloxidase activation is not required for survival to microbial infections in Drosophila.

PubMed ID: 16322759

DOI: 10.1038/sj.embor.7400592

PubMed ID: 18801354

Title: Drosophila Serpin-28D regulates hemolymph phenoloxidase activity and adult pigmentation.

PubMed ID: 18801354

DOI: 10.1016/j.ydbio.2008.08.030

PubMed ID: 22227521

Title: Genetic evidence of a redox-dependent systemic wound response via Hayan protease-phenoloxidase system in Drosophila.

PubMed ID: 22227521

DOI: 10.1038/emboj.2011.476

PubMed ID: 24260243

Title: Serine protease MP2 activates prophenoloxidase in the melanization immune response of Drosophila melanogaster.

PubMed ID: 24260243

DOI: 10.1371/journal.pone.0079533

PubMed ID: 24788090

Title: Prophenoloxidase activation is required for survival to microbial infections in Drosophila.

PubMed ID: 24788090

DOI: 10.1371/journal.ppat.1004067

Sequence Information:

  • Length: 447
  • Mass: 49795
  • Checksum: 99E78A2C9E0411E1
  • Sequence:
    • MTKMGGNLAV MLLSLFLSAL ATGNGNSIPT TTTPQGVFET RTDKLPGGAA SVPSGAGIYD 
DIDTFVPFRS DSHDPFSWHL LKTVLQNETA DKNVIISPFS VKLVLALLAE AAGAGTQTQV 
ELANTQTDIR SQNNVREFYR KTLNSFKKEN QLHETLSVRT KLFTDSFIET QQKFTATLKH 
FYDSEVEALD FTNPEAAADA INAWAANITQ GRLQQLVAPD NVRSSVMLLT NLIYFNGLWR 
RQFATTFQGS FFRSKDDQSR AEFMEQTDYF YYTTSEKLKA QILRLPYKGK NSLFVLLPYA 
LNGIHDLVKN LENDELKSAQ WAMEEVKVKV TLPKFHFDYQ QNLKETLRSL GVREIFEDSA 
SLPGLTRGAD VAGKVKVSNI LQKAGINVNE KGTEAYAATV VEIENKFGGS TAIEEFNVNR 
PFVFFIEEES TGNILFAGKV HSPTTQN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.