Nup214 | FBgn0010660 | NCBI 46091

Details for: Nup214

Gene ID: 46091

Symbol: Nup214

Ensembl ID: FBgn0010660

Description: Nucleoporin 214kD

Associated with

Cell cycle
(R-DME-1640170)
Cell cycle, mitotic
(R-DME-69278)
Gene expression (transcription)
(R-DME-74160)
Gene silencing by rna
(R-DME-211000)
Hur (elavl1) binds and stabilizes mrna
(R-DME-450520)
Metabolism of proteins
(R-DME-392499)
Metabolism of rna
(R-DME-8953854)
Mitotic anaphase
(R-DME-68882)
Mitotic metaphase and anaphase
(R-DME-2555396)
Mitotic prophase
(R-DME-68875)
M phase
(R-DME-68886)
Nuclear envelope (ne) reassembly
(R-DME-2995410)
Nuclear envelope breakdown
(R-DME-2980766)
Nuclear pore complex (npc) disassembly
(R-DME-3301854)
Post-translational protein modification
(R-DME-597592)
Postmitotic nuclear pore complex (npc) reformation
(R-DME-9615933)
Processing of capped intron-containing pre-mrna
(R-DME-72203)
Regulation of mrna stability by proteins that bind au-rich elements
(R-DME-450531)
Sumo e3 ligases sumoylate target proteins
(R-DME-3108232)
Sumoylation
(R-DME-2990846)
Sumoylation of chromatin organization proteins
(R-DME-4551638)
Sumoylation of dna damage response and repair proteins
(R-DME-3108214)
Sumoylation of dna replication proteins
(R-DME-4615885)
Sumoylation of sumoylation proteins
(R-DME-4085377)
Transcriptional regulation by small rnas
(R-DME-5578749)
Transport of mature mrna derived from an intron-containing transcript
(R-DME-159236)
Transport of mature mrna derived from an intronless transcript
(R-DME-159231)
Transport of mature mrnas derived from intronless transcripts
(R-DME-159234)
Transport of mature transcript to cytoplasm
(R-DME-72202)
Transport of the slbp dependant mature mrna
(R-DME-159230)
Transport of the slbp independent mature mrna
(R-DME-159227)
Negative regulation of protein export from nucleus
(GO:0046826)
Nuclear envelope
(GO:0005635)
Nuclear localization sequence binding
(GO:0008139)
Nuclear pore
(GO:0005643)
Positive regulation of rna export from nucleus
(GO:0046833)
Protein binding
(GO:0005515)
Protein import into nucleus
(GO:0006606)
Protein localization to nuclear pore
(GO:0090204)
Rna export from nucleus
(GO:0006405)
Structural constituent of nuclear pore
(GO:0017056)

Other Information

Proteins

Nuclear pore complex protein Nup214

Genular Protein ID: 4007196464

Symbol: NU214_DROME

Name: Nuclear pore complex protein Nup214

UniProtKB Accession Codes:

Q9W1X4 Q8T3K4

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 14638854

Title: The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export.

PubMed ID: 14638854

DOI: 10.1083/jcb.200304046

PubMed ID: 17032737

Title: The nucleoporin Nup214 sequesters CRM1 at the nuclear rim and modulates NFkappaB activation in Drosophila.

PubMed ID: 17032737

DOI: 10.1242/jcs.03201

PubMed ID: 17682050

Title: Distinct functions of the Drosophila Nup153 and Nup214 FG domains in nuclear protein transport.

PubMed ID: 17682050

DOI: 10.1083/jcb.200612135

PubMed ID: 20547758

Title: Specific nucleoporin requirement for Smad nuclear translocation.

PubMed ID: 20547758

DOI: 10.1128/mcb.00124-10

Sequence Information:

Length: 1711
Mass: 175176
Checksum: 7C73E46C789E55ED
Sequence:

MAQNAPDCED TQDFQFKLHH KIVAFKKCGE PRSNVNLLAV SSSRGLLFAG SPTQPELKVI 
IVKDLVNAKS TAQQPQARLV PLPSIPNYIA CSSDGNLLAV NHTQNGTSLL SIYAVLSFMT 
PDVRPVYNIR LAAEDHVHGV QLLWNPVLPN SLAVVLSNGA LAMYALKEGG NFEMHSLDKN 
QQVKCGCWSP KGKQIVLGFP GGTVKQFKPD LTLAKTLLCP PNIHDAPFDT IAIQWLSTFQ 
FAVIFLQHGE DCSPSLYILN APKAGAPSYI NYYDICYSMN GPRNHQFVFS HVPQWNLLLV 
VSANGVEVGI MRSTEAGDTP AWQQLTLLDE ARIEMPLSED KDETFPLGFA FDTSTTHQLT 
INEKKLQTMP MVHVLSSDGE LLSFNFLNVL PTAVSVCSPP PPVADTSGQF KPLNMLLASE 
EEEQPAWAAS PSKAPAATPA ASSDISFAFT PNTVTSTPAP SKDKQPSLFS GFGAAAAKAP 
APQLSFGTAP TSSPVSFGAP TTNAAKPTTP FGGFGTQATT TAMGSMFSAS GANAFGGMAL 
NKPAIASVTP RTAAPGSTVP ATPASAPANK PLYTVPLTFT PVDTKPATSA PPQIADESLK 
PDDTEPIIKD MIALQIEAFS KDIQKQKEQT KELLKGIAAP SALRAYAKRL DDLQELNEQA 
KDVEFELDVQ GLRQGLNEAY AIVAECRGKL EIYRKPEITR LMNSSSCDPS GRRMLARLQS 
YVAANEAQLR LAQQHVDLQW EQFQDVVRRN SKSRMHMPCL EGIYQRLTRL QNLTSNQRIV 
QNNIKSKLKE RGLLQAALLD QEKSRTRTNE AVDTLTDSIL TMSLSQVVDS NAAKLTRERL 
QKIRNIVQLQ KINVICPQRP DRVGLKSEVI LETKRRAEQI KRAAAKPATA NKYTQAAVAP 
PSPPDVAPTP AVAPMPQATV TVAPPLPKPM PSIPSVVEKP GVPTHPTTPV ATPFSFSQSI 
PFVKTSTVTP TTNTVTPGEA AKPGLSIFGG STISSFSFGG GAAKSALSFG TGSPAVAAPT 
PKPNPLSAVE KPTPEPTKPK EQKAAESKEF KAVQPETEES KVPQKPKAET ENKSFGFGGF 
TGTGGTVGNT SSSPFSFGGL GSSLGFGGTA AAVPKSEPSS TATTSVATSA STAPFGIFSA 
ALAKPSNSEP ITTVTSNTTT ITSKPTNVIA SSSVTDAPSV TTTNAVTSST DPIGGLFSSV 
TICKPNTPAD TTKPANIFGG GLSAGSFSFG GTIDASKGLF GSTKPVATAP TSVTEANNKT 
DPISTTPSAI STTTATTTVS SPAVVPAAVT AAVPATSSTT VTSSTAVPGS AFSFSNAFST 
LSAGGAAAPT TSASAPLAAK SPTATSTGNN SSNSVFGGGF AVATSTAAPV ASPFQSAAKS 
PVSSANIFGS IPKAETSVFG GATTAPSNTT AAATPDAPPA GLFASAAISN PSPFGSPTTR 
APASGGNIFG QAVKPSVFGQ PAQAGDSGGS IFGGGSASTP FGSSSIFGGG NTQGAVGAPA 
AGSTSIFGQK VFGQSSAAAP AAGGNIFSNP VGSPQASPFG GGGNSIFGSP ATAPPASGGS 
IFGGGSSSGG FGSFTQTTPA QGGFGGGFGQ GGGGSVAQTG FGSPQAPQQQ TTTPGGFGAK 
PVFGGSPAFG ASPTFGGGAT FGSPKGFGGF GGASPVASPP PFGAAAKPAQ GNIFETLGGQ 
ESGLSFGNLA QTGNSNAQKP AFGGSSFMNY R

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nup214

Associated with

Other Information

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export. PubMed ID: 14638854

The nucleoporin Nup214 sequesters CRM1 at the nuclear rim and modulates NFkappaB activation in Drosophila. PubMed ID: 17032737

Distinct functions of the Drosophila Nup153 and Nup214 FG domains in nuclear protein transport. PubMed ID: 17682050

Specific nucleoporin requirement for Smad nuclear translocation. PubMed ID: 20547758